Questions and Answers
What class of medication does Lansoprazole belong to?
What is the mechanism of action (MOA) of Lansoprazole?
Binds to an enzyme on gastric parietal cells, preventing transport of hydrogen ions into the gastric lumen.
Which of the following are indications for Lansoprazole? (Select all that apply)
What are some contraindications for using Lansoprazole?
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What are possible adverse effects of Lansoprazole? (Select all that apply)
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What patient teaching should be given regarding Lansoprazole?
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Lansoprazole may cause dizziness as a side effect.
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What is a unique differential for Lansoprazole?
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Study Notes
Lansoprazole Overview
- Class: Proton Pump Inhibitors (PPIs), used to reduce gastric acid production.
Mechanism of Action (MOA)
- Binds specifically to an enzyme on gastric parietal cells under acidic conditions.
- Inhibits the transport of hydrogen ions into the gastric lumen.
- Results in decreased gastric acid accumulation, alleviating reflux and promoting healing of duodenal ulcers.
Indications for Use
- Erosive esophagitis: Inflammation of the esophagus due to acid damage.
- Duodenal ulcers: Sores on the lining of the duodenum.
- Active benign gastric ulcers: Non-cancerous stomach ulcers.
- Gastroesophageal reflux disease (GERD): A chronic condition where stomach acid flows back into the esophagus.
Contraindications
- Hypersensitivity to lansoprazole or any component of the formulation.
- Classified as pregnancy category B, indicating no proven risk in human studies but caution is advised.
Adverse Effects
- Common adverse effects include dizziness, headache, and gastrointestinal issues such as diarrhea and abdominal pain.
- Risk of pseudomembranous colitis, a severe inflammation of the colon.
- Potential increase in bone fracture risk.
Patient Teaching Guidelines
- Inform patients about dizziness as a possible side effect; advise against driving until they know how the medication affects them.
- Emphasize adherence to the prescribed treatment duration, even if symptoms improve.
- Stress the importance of avoiding double dosing.
- Recommend avoiding NSAIDs, alcohol, and specific foods that may cause stomach discomfort.
- Advise immediate reporting of symptoms like black, tarry stools, diarrhea, abdominal pain, or persistent headaches.
Unique Differences
- Notable side effect includes dizziness particularly affecting the central nervous system (CNS).
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Description
Test your knowledge on Lansoprazole, a proton pump inhibitor, through this set of flashcards. Each card covers important aspects such as its mechanism of action, indications, and terminology related to its use in treating gastrointestinal conditions.
