Lab No. 5: Blood Transfusion Reactions

The O-A-B and Rh systems.

Type A blood contains anti-B antibodies.

They undergo clumping and hydrolysis, losing their functions.

<p>Rh+ blood has Rh antigens, while Rh- blood does not.</p> Signup and view all the answers

<p>Type O blood contains both anti-A and anti-B antibodies.</p> Signup and view all the answers

<p>Antigens on red blood cells trigger antibody responses that can lead to reactions.</p> Signup and view all the answers

<p>It allows quick identification of a patient's blood type to ensure safe transfusions.</p> Signup and view all the answers

<p>It can lead to acute hemolytic reactions.</p> Signup and view all the answers

<p>Knowing one's blood type is crucial for safe blood transfusions and can influence medical decisions in emergencies.</p> Signup and view all the answers

<p>Yes, knowing your blood type can inform dietary choices and lifestyle adjustments, as well as risk assessment for certain diseases.</p> Signup and view all the answers

<p>Materials needed include anti-A, anti-B, anti-D reagents, a glass slide, a dropper, and a lancet.</p> Signup and view all the answers

<p>The procedure involves adding specific anti-sera to a glass slide, collecting a blood sample from the fingertip, and mixing it with the reagents to observe reactions.</p> Signup and view all the answers

<p>Antigen-antibody reactions occur when antibodies bind to specific antigens present on the surface of cells, leading to immune responses.</p> Signup and view all the answers

<p>Thrombin is essential for converting fibrinogen into fibrin, forming the structural framework of a blood clot.</p> Signup and view all the answers

<p>The intrinsic pathway is activated by foreign surfaces during vascular damage, while the extrinsic pathway is initiated by tissue damage exposing collagen.</p> Signup and view all the answers

<p>Prolonged clotting time can indicate a deficiency or dysfunction of clotting factors like prothrombin.</p> Signup and view all the answers

<p>To assess the blood vessel constriction and platelet action in stopping bleeding without clot formation.</p> Signup and view all the answers

<p>Clotting time (PT) normal range is 6-10 minutes and bleeding time (BT) normal range is 2-5 minutes.</p> Signup and view all the answers

<p>The volunteer must not have liver diseases and should not be on anticoagulant medications.</p> Signup and view all the answers

<p>The volunteer wipes blood on the corresponding time mark on the filter paper.</p> Signup and view all the answers

<p>The endpoint signifies the formation of a clot, which is crucial for determining the clotting time.</p> Signup and view all the answers

<p>The capillary tube fills automatically with blood and is periodically broken to check for clot formation.</p> Signup and view all the answers

<p>Anticoagulant medications can significantly affect the results of bleeding time tests.</p> Signup and view all the answers

<p>Every 30 seconds, the blood should be pulled up with a lancet tip or needle syringe.</p> Signup and view all the answers

<p>Any medications, supplements, or herbs being taken should be disclosed.</p> Signup and view all the answers

<p>A diet full of green and leafy vegetables may prolong clotting time.</p> Signup and view all the answers

<p>The normal range of platelets is typically between 150,000 and 450,000 platelets per microliter of blood.</p> Signup and view all the answers

<p>Platelets help in the formation of a temporary plug at the site of injury and release chemicals to promote clotting.</p> Signup and view all the answers

<p>The two main types of clot are the primary clot and the secondary clot.</p> Signup and view all the answers