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Lab 3: Autosomal Dominant Polycystic Kidney Disease (ADPKD)

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Lab 3: Autosomal Dominant Polycystic Kidney Disease (ADPKD)

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Questions and Answers

What is the main cause of renal failure worldwide?

Multifactorial polycystic kidney disease

Mitochondrial polycystic kidney disease

Autosomal recessive polycystic kidney disease

Autosomal dominant polycystic kidney disease (correct)

At what age do symptoms of ADPKD usually start?

In adults under 20

In adults over 30 (correct)

In older adults over 60

In children under 10

What is used to check for blood or protein in urine?

Genetic tests

Scans

Urine tests (correct)

Blood tests

Why may an MRI scan be recommended?

To check for brain aneurysms Signup and view all the answers

How many genes are affected in polycystic kidney disease?

Two Signup and view all the answers

What percentage of cases of ADPKD are caused by the PKD1 gene?

78% Signup and view all the answers

What percentage of ADPKD cases is attributed to PKD2?

15% Signup and view all the answers

Which type of PKD tends to have more severe symptoms?

PKD1 Signup and view all the answers

What is the purpose of molecular genetic testing in ADPKD?

To provide essential reagents for molecular diagnosis Signup and view all the answers

Lab 3: Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Choose a study mode

Podcast

Questions and Answers

What is the main cause of renal failure worldwide?

At what age do symptoms of ADPKD usually start?

What is used to check for blood or protein in urine?

Why may an MRI scan be recommended?

How many genes are affected in polycystic kidney disease?

What percentage of cases of ADPKD are caused by the PKD1 gene?

What percentage of ADPKD cases is attributed to PKD2?

Which type of PKD tends to have more severe symptoms?

What is the purpose of molecular genetic testing in ADPKD?

What is the volume of the multiplex PCR reaction mixture?

What is the final step in the thermal cycling program?

What follows the multiplex PCR reaction?

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