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Kinetochores and Chromosome Movement

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Questions and Answers

What role do kinetochores play during cell division?

They initiate the formation of the spindle apparatus.

They facilitate the separation of homologous chromosomes.

They regulate the timing of cytokinesis.

They serve as attachment points for microtubules during chromosome movement. (correct)

During which phase of mitosis are chromosomes aligned at the metaphase plate?

Metaphase (correct)

Anaphase

Telophase

Prophase

What occurs to sister chromatids during anaphase?

They separate and move to opposite ends of the cell. (correct)

They undergo replication.

They migrate towards the spindle's equator.

They remain attached to each other.

How do microtubules facilitate the movement of chromosomes during cell division?

<p>By shortening through depolymerization at the kinetochore ends.</p> Signup and view all the answers

What is the metaphase plate?

<p>An imaginary line where chromosomes align in the middle of the cell.</p> Signup and view all the answers

Study Notes

Kinetochores

Kinetochores are protein complexes located at centromeres.
During prometaphase, spindle microtubules attach to kinetochores, initiating chromosome movement.
At metaphase, chromosomes align at the metaphase plate, the central point between spindle poles.
In anaphase, sister chromatids separate and move to opposite poles along kinetochore microtubules.
Kinetochore microtubules shorten by depolymerizing at their kinetochore ends.

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Description

This quiz explores the role of kinetochores in cell division, detailing their function during the different phases of mitosis. Understand how kinetochore microtubules contribute to the alignment and separation of chromosomes. Test your knowledge on the critical stages of prometaphase, metaphase, and anaphase.