Kidney HCO3 Reabsorption Process

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Questions and Answers

What percentage of HCO3- is reabsorbed by the distal tubules in the kidneys?

  • 25%
  • 15% (correct)
  • 85%
  • 5%

How is HCO3- primarily reabsorbed in the tubules?

  • As CO2 (correct)
  • By active transport
  • As carbonic acid
  • Directly as HCO3-

What happens when HCO3- is filtered in excess of H+ available?

  • Excess HCO3- is lost in urine (correct)
  • All HCO3- is reabsorbed with H+
  • HCO3- combines with CO2
  • HCO3- forms more carbonic acid

What percentage of HCO3- is typically reabsorbed from the tubules?

<p>Nearly 100% (D)</p> Signup and view all the answers

Why is HCO3- reabsorbed slightly less effectively in the distal tubules?

<p>Slight permeability to HCO3- (C)</p> Signup and view all the answers

Flashcards

Bicarbonate Reabsorption in Proximal Tubules

The majority, about 85%, of bicarbonate ions (HCO3-) are reabsorbed back into the bloodstream from the kidney tubules.

Bicarbonate Reabsorption in Distal Tubules

The remaining 15% of bicarbonate ions are reabsorbed in the distal tubules.

Reabsorption of Bicarbonate as CO2

Because tubules have limited permeability to bicarbonate ions, these ions are primarily reabsorbed as carbon dioxide (CO2).

Bicarbonate and Hydrogen Ion Interaction

When bicarbonate ions (HCO3-) enter the tubules, they combine with hydrogen ions (H+) to form carbonic acid (H2CO3).

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Carbonic acid Dissociation and CO2 Diffusion

Carbonic acid then breaks down into water (H2O) and carbon dioxide (CO2), allowing the CO2 to diffuse back into the extracellular fluid (ECF).

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Study Notes

Kidney HCO3 Reabsorption

  • 85% of HCO3- is reabsorbed in the proximal tubules, 15% in distal tubules.
  • Tubules have limited permeability to HCO3-.
  • Reabsorption primarily occurs as CO2.
  • HCO3- combines with H+ to form carbonic acid.
  • Carbonic acid dissociates into water (Hâ‚‚O) and CO2.
  • CO2 diffuses back into the extracellular fluid (ECF).
  • Nearly all filtered HCO3- is normally reabsorbed.
  • Excess HCO3- (beyond available H+) is excreted in urine.

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