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Kidney Function Tests in Biochemistry: Interpretation and Indications Quiz

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Kidney Function Tests in Biochemistry: Interpretation and Indications Quiz

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Questions and Answers

What is the formula to calculate 24-hour creatinine clearance?

Creatinine in blood x total urine volume / creatinine in urine

Creatinine in urine x total urine volume / creatinine in blood (correct)

Creatinine in blood x total urine volume x 24 hours

Creatinine in urine / creatinine in blood x 24 hours

What is the normal range for serum creatinine levels?

20 mg/dL or less

1.4-4.6 mg/dL

0.7-1.4 mg/dL (correct)

105 ± 20 mL/min

What is the clinical significance of measuring serum uric acid levels?

To assess kidney function

To diagnose gout

To monitor purine metabolism

All of the above (correct)

What is the normal range for serum uric acid levels?

1.4-4.6 mg/dL Signup and view all the answers

What is the earliest sign of renal damage?

Microalbuminuria Signup and view all the answers

Which of the following is not a renal function test?

Serum glucose Signup and view all the answers

What is the primary indicator of kidney health mentioned in the text?

Serum creatinine levels Signup and view all the answers

Which of the following is NOT an indication for performing kidney function tests?

Diagnose diabetes mellitus Signup and view all the answers

How is creatinine removed from the body?

By both glomerular filtration and proximal tubular secretion Signup and view all the answers

What does a decrease in glomerular filtration rate (GFR) indicate?

Renal impairment Signup and view all the answers

What is the formula for calculating creatinine clearance?

Urine creatinine concentration (mg/dl) × Volume of urine in 24 hrs (ml/min) / Plasma creatinine Signup and view all the answers

What factors can cause a decrease in GFR besides renal impairment?

Congestive cardiac failure and dehydration Signup and view all the answers

Study Notes

Renal Function Tests

The formula to calculate 24-hour creatinine clearance is: Urine creatinine (mg/24hr) / Serum creatinine (mg/dL) x 1440 (min) / Body weight (kg) x 100.

Serum Creatinine Levels

The normal range for serum creatinine levels is 0.5-1.1 mg/dL.

Serum Uric Acid Levels

The clinical significance of measuring serum uric acid levels is to assess renal function and detect abnormalities.
The normal range for serum uric acid levels is 3.5-7.2 mg/dL.

Renal Damage

The earliest sign of renal damage is a decrease in glomerular filtration rate (GFR).

Renal Function Tests

The primary indicator of kidney health is creatinine clearance.
Electrolyte panel is not a renal function test.

Indications for Kidney Function Tests

There is no indication for performing kidney function tests in healthy individuals with no risk factors.

Creatinine Removal

Creatinine is removed from the body through glomerular filtration.

Glomerular Filtration Rate (GFR)

A decrease in GFR indicates renal impairment or kidney damage.

Factors Affecting GFR

Factors that can cause a decrease in GFR besides renal impairment include: age, sex, muscle mass, and some medications.

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Description

Test your knowledge on interpreting various kidney function tests and understanding the indications for Kidney Function Tests (KFT) in the field of biochemistry. Learn about assessing kidney damage, monitoring effects of renal toxic drugs, and tracking the progression of renal damage.