Creatinine and Kidney Function Quiz
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Questions and Answers

What is the chemical waste product in the blood that passes through the kidneys to be filtered and eliminated in urine?

Creatinine

What is the function of creatinine in evaluating kidney function?

Creatinine helps evaluate kidney function.

How is creatine synthesized in the body?

Creatine is synthesized in the liver from arginine, glycine, and methionine.

What factors determine the plasma creatinine concentration?

<p>Plasma creatinine concentration is a function of relative muscle mass, rate of creatine turnover, and renal function.</p> Signup and view all the answers

How is creatinine excreted from the body?

<p>Creatinine is filtered by the glomerulus and excreted in urine.</p> Signup and view all the answers

What is the principle behind the Jaffe's reaction for determining creatinine?

<p>Creatinine reacts with alkaline picrate to produce an orange-yellow color.</p> Signup and view all the answers

Why is it important to measure the volume of collected urine accurately when determining creatinine levels?

<p>To ensure the correct concentration of creatinine is obtained for accurate results.</p> Signup and view all the answers

What specimen is required for creatinine determination using the Jaffe reaction?

<p>Unhaemolysed serum, plasma in heparin or EDTA tube, or urine (diluted and multiplied by 20).</p> Signup and view all the answers

In what clinical scenario do serum creatinine levels start to increase?

<p>Serum creatinine levels do not start to rise until renal function has decreased by at least 50%.</p> Signup and view all the answers

What are some factors that can lead to an increase in creatinine levels in the blood?

<p>Blocked urinary tract, high protein diet, dehydration, kidney problems, sufficiency of kidney function, severity of kidney damage, and reduced blood flow to the kidney.</p> Signup and view all the answers

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