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Questions and Answers
What is the primary reason diabetes type II is most often associated with older age?
What is the primary reason diabetes type II is most often associated with older age?
Which factor is NOT typically associated with an increased risk of developing diabetes type II?
Which factor is NOT typically associated with an increased risk of developing diabetes type II?
What initial condition typically characterizes the development of diabetes type II?
What initial condition typically characterizes the development of diabetes type II?
Which statement best describes the function of insulin in the body?
Which statement best describes the function of insulin in the body?
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Which of the following symptoms is NOT associated with Type 2 diabetes?
Which of the following symptoms is NOT associated with Type 2 diabetes?
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Which of the following statements about diabetes type II is correct?
Which of the following statements about diabetes type II is correct?
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What is a characteristic feature of metabolic syndrome?
What is a characteristic feature of metabolic syndrome?
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Which condition is primarily associated with excessive thirst due to dehydration?
Which condition is primarily associated with excessive thirst due to dehydration?
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Which medication is known to improve insulin sensitivity in Type 2 diabetic patients?
Which medication is known to improve insulin sensitivity in Type 2 diabetic patients?
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Which symptom indicates a potential state of metabolic acidosis in diabetic patients?
Which symptom indicates a potential state of metabolic acidosis in diabetic patients?
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What is a common complication seen in noncompliant diabetic patients?
What is a common complication seen in noncompliant diabetic patients?
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Which combination of factors qualifies as metabolic syndrome?
Which combination of factors qualifies as metabolic syndrome?
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What can excessive hunger and eating in diabetic patients indicate?
What can excessive hunger and eating in diabetic patients indicate?
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What symptom is often caused by the body's use of protein and fat for energy in diabetes?
What symptom is often caused by the body's use of protein and fat for energy in diabetes?
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Which factor is commonly associated with the risk of developing Type 2 diabetes?
Which factor is commonly associated with the risk of developing Type 2 diabetes?
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What is the primary function of glucagon?
What is the primary function of glucagon?
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Which cells in the pancreas are responsible for producing insulin?
Which cells in the pancreas are responsible for producing insulin?
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What happens to blood glucose levels when insulin is secreted?
What happens to blood glucose levels when insulin is secreted?
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What is the role of somatostatin in glucose regulation?
What is the role of somatostatin in glucose regulation?
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Which test is used to assess long-term glycemic control over the previous 120 days?
Which test is used to assess long-term glycemic control over the previous 120 days?
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When is it recommended to perform a Hemoglobin A1C test for someone who has stable blood glucose control?
When is it recommended to perform a Hemoglobin A1C test for someone who has stable blood glucose control?
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What physiological response does glucagon initiate in response to low blood glucose levels?
What physiological response does glucagon initiate in response to low blood glucose levels?
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Which of the following best describes the secretion control of insulin?
Which of the following best describes the secretion control of insulin?
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What is considered the expected reference range for Hemoglobin A1C?
What is considered the expected reference range for Hemoglobin A1C?
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What is the significance of the Oral Glucose Tolerance Test (OGTT)?
What is the significance of the Oral Glucose Tolerance Test (OGTT)?
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What is the blood creatinine level indicative of Stage 1 acute kidney injury?
What is the blood creatinine level indicative of Stage 1 acute kidney injury?
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Which stage of acute kidney injury is characterized by a urine output of less than 0.5 mL/kg/hr for 12 hours or more?
Which stage of acute kidney injury is characterized by a urine output of less than 0.5 mL/kg/hr for 12 hours or more?
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What best describes prerenal acute kidney injury?
What best describes prerenal acute kidney injury?
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What is a common laboratory finding in acute kidney injury?
What is a common laboratory finding in acute kidney injury?
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What urine specific gravity level is typically seen in prerenal acute kidney injury?
What urine specific gravity level is typically seen in prerenal acute kidney injury?
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Which imaging assessment provides 3-dimensional imaging of the renal/urinary system?
Which imaging assessment provides 3-dimensional imaging of the renal/urinary system?
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What is a primary nursing action before performing a CT scan involving contrast?
What is a primary nursing action before performing a CT scan involving contrast?
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What is a potential complication of a kidney biopsy?
What is a potential complication of a kidney biopsy?
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What is NOT a characteristic of intrarenal acute kidney injury?
What is NOT a characteristic of intrarenal acute kidney injury?
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During the recovery phase of acute kidney injury, how long can it take for kidney function to be fully restored?
During the recovery phase of acute kidney injury, how long can it take for kidney function to be fully restored?
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Which nursing action is essential before a client undergoes abdominal imaging?
Which nursing action is essential before a client undergoes abdominal imaging?
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What electrolyte imbalance is common in intrarenal azotemia?
What electrolyte imbalance is common in intrarenal azotemia?
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What is the expected initial urine output for a patient experiencing Stage 3 acute kidney injury?
What is the expected initial urine output for a patient experiencing Stage 3 acute kidney injury?
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What finding in a urinalysis suggests acute kidney injury?
What finding in a urinalysis suggests acute kidney injury?
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What should be consumed to meet carbohydrate needs if solid food is not an option?
What should be consumed to meet carbohydrate needs if solid food is not an option?
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What is the recommended frequency for testing urine for ketones if blood glucose exceeds 240 mg/dL?
What is the recommended frequency for testing urine for ketones if blood glucose exceeds 240 mg/dL?
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Which symptom indicates a need to call the provider immediately?
Which symptom indicates a need to call the provider immediately?
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What is a major risk factor for the development of myocardial infarction related to diabetes?
What is a major risk factor for the development of myocardial infarction related to diabetes?
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Which complication results from prolonged hyperglycemia and can lead to foot ulcers?
Which complication results from prolonged hyperglycemia and can lead to foot ulcers?
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What is a common gastrointestinal issue associated with diabetic autonomic neuropathy?
What is a common gastrointestinal issue associated with diabetic autonomic neuropathy?
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Which test result is typical in Diabetic Ketoacidosis (DKA)?
Which test result is typical in Diabetic Ketoacidosis (DKA)?
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Which of the following is NOT a characteristic of Hyperglycemic Hyperosmolar State (HHS)?
Which of the following is NOT a characteristic of Hyperglycemic Hyperosmolar State (HHS)?
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What is a common cause for the development of neonvascularization in diabetic retinopathy?
What is a common cause for the development of neonvascularization in diabetic retinopathy?
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In the context of diabetes complications, what does microalbuminuria indicate?
In the context of diabetes complications, what does microalbuminuria indicate?
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What initial action should be taken if a patient experiences mild hypoglycemia?
What initial action should be taken if a patient experiences mild hypoglycemia?
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In the case of diabetic peripheral neuropathy, what is one of the first symptoms reported?
In the case of diabetic peripheral neuropathy, what is one of the first symptoms reported?
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Which treatment option should be considered when potassium levels fall below 5.0 after hyperglycemic treatment?
Which treatment option should be considered when potassium levels fall below 5.0 after hyperglycemic treatment?
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Study Notes
Acute Kidney Injury (AKI)
- Diuresis occurs when kidneys start recovering, leading to significant fluid loss that can last 2-6 weeks.
- Complete kidney function recovery can take up to 12 months after initiating treatment.
Classes of AKI
-
Stage 1 (Risk Stage):
- Blood creatinine levels 1.5-1.9 times baseline.
- Urine output < 0.5 mL/kg/hr for 6 hours or more.
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Stage 2 (Injury Stage):
- Blood creatinine levels 2-2.9 times baseline.
- Urine output < 0.5 mL/kg/hr for 12 hours or more.
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Stage 3 (Failure Stage):
- Blood creatinine levels 3 times baseline.
- Urine output < 0.3 mL/kg/hr for 12 hours or more.
Types of AKI
-
Prerenal AKI:
- Caused by volume depletion or reduced blood flow to kidneys leading to nephron ischemia.
- Early intervention can reverse AKI and prevent chronic kidney disease (CKD).
-
Intrarenal AKI:
- Direct kidney damage from lack of oxygen affecting glomeruli, nephrons, or tubules.
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Postrenal AKI:
- Resulting from bilateral obstruction of structures leaving the kidney.
Laboratory Findings
- Blood creatinine levels may rise by 1-2 mg/dL every 24-48 hours, or by 1-6 mg/dL in a week.
- Blood urea nitrogen (BUN) may increase to 80-100 mg/dL within a week.
- Urine specific gravity can vary; elevated in prerenal, and diluted in intrarenal AKI.
- Electrolyte changes: sodium levels may decrease or increase, along with hyperkalemia and hyperphosphatemia.
- Decreased hematocrit levels and presence of sediment in urinalysis indicate AKI.
- Arterial blood gas (ABG) analysis may show metabolic acidosis.
Imaging Assessments
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MAG3 and standard X-rays (KUB):
- Visualizes renal structures and detects obstructions or stones without contrast media.
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CT Scan:
- Offers detailed 3D imaging to assess kidney size and possible obstructions, using iodine-based contrast.
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Ultrasound (US):
- Assesses kidney size and evaluates lower urinary tract for obstructions and calculi.
Other Diagnostic Assessments
-
Kidney Biopsy:
- Tissue samples can be taken to examine for complications such as hemorrhage, infection, urinary retention, or liver/bowel puncture.
- Nursing Actions: NPO for 4 hours before procedure, client positioned prone, monitor hemoglobin levels.
Diabetes Mellitus (DM) Overview
- Pancreas Function: Regulates digestion and glucose metabolism via hormone secretion.
- Alpha Cells: Secrete glucagon to raise blood sugar during fasting.
- Beta Cells: Produce insulin, which manages blood sugar levels post-meals.
Glucagon and Insulin Functions
-
Glucagon:
- Stimulates glycogenolysis and gluconeogenesis to prevent hypoglycemia.
-
Insulin:
- Facilitates glucose uptake, promotes glycogenesis, and prevents hyperglycemia.
Diabetes Mellitus Type II
- Progressive condition often beginning with insulin resistance and leading to decreased insulin secretion.
- Common in obese individuals; linked to genetics, metabolic syndrome, and lifestyle factors.
- Symptoms include increased thirst, frequent urination, dark patches on skin, and fatigue.
Metabolic Syndrome
- Defined by the presence of 3+ risk factors including abdominal obesity and hypertension, increasing the likelihood of DM2 and cardiovascular events.
Diabetes Management and Medications
- Medications such as Metformin enhance insulin sensitivity, reduce liver glucose production, and may lead to lactic acidosis in certain patients.
- Regular monitoring of blood glucose levels and HbA1c is necessary for maintaining glycemic control.
- Aspirin therapy recommended for heart disease prevention in at-risk patients.### Hydration and Nutrition Management
- Consume sugar-free, non-caffeinated liquids hourly to prevent dehydration.
- If blood glucose is below the target, fluids containing sugar are permitted.
- Meet carbohydrate needs through soft foods (custard, cream soup, gelatin, graham crackers) six to eight times daily or replace with liquids equivalent to the usual carb content.
- Test urine for ketones every 3-4 hours or if blood glucose exceeds 240 mg/dL, and report values outside the expected range.
- Seek medical assistance for:
- Moderate to large urine ketones persisting over 24 hours.
- Persistent blood glucose above 250 mg/dL despite treatment.
- Persistent fever over 101.5°F unresponsive to acetaminophen.
- Symptoms of disorientation, rapid breathing, or persistent gastrointestinal upset.
- Illness lasting longer than 2 days.
Complications of Diabetes Mellitus
-
Macrovascular Complications:
- Coronary artery disease is a leading risk factor for myocardial infarction.
- Hypertension affects 75% of people with diabetes.
- Stroke risk increases 2-4 times in individuals with diabetes.
- Peripheral vascular disease primarily affects lower extremities with potential gangrene due to hyperglycemia.
-
Neuropathy (Microvascular Complication):
- Caused by microvascular disease, leading to conditions like microalbuminuria and nerve dysfunction.
- Risks include mood alterations and increased susceptibility to infections.
-
Diabetic Peripheral Neuropathy:
- Progressive nerve function deterioration, causing sensory loss with slow onset.
- Can lead to fallen ulcers and deformities.
-
Diabetic Autonomic Neuropathy:
- Affects heart and blood vessel nerves, causing orthostatic hypotension and potential for falls.
- Can disrupt gastrointestinal functioning, leading to issues like gastroparesis and constipation.
-
Retinopathy:
- Leading cause of blindness related to retinal microvascular damage.
- Nearly all diabetics exhibit some level of diabetic retinopathy, which usually presents few symptoms until vision loss occurs.
Diabetic Ketoacidosis (DKA)
- Caused by insufficient insulin or interruptions in treatment, often triggered by infections, stress, or illness.
- Commonly presents with:
- Hyperglycemia (blood glucose >300 mg/dL).
- Elevated ketones in blood and urine.
- High blood osmolarity and signs of metabolic acidosis.
- Dehydration indicated by high BUN (>30 mg/dL) and creatinine (>1.5 mg/dL).
Hyperglycemic Hyperosmolar State (HHS)
- Results from poorly managed diabetes, often in older adults, leading to severe hyperglycemia (>600 mg/dL) without ketoacidosis.
- Occurs due to inadequate fluid intake or compromised kidney function.
- Presents with high blood osmolarity (>320 mOsm/L) and elevated BUN and creatinine.
Hypoglycemia
- Defined as blood sugar below 70 mg/dL.
- Symptoms range from mild (hunger, headache, sweating) to severe (confusion, seizures, coma).
- Treatment includes 15g of fast-acting sugar for mild hypoglycemia; severe cases may require hospitalization and glucagon administration.
- Position the unconscious client laterally to prevent aspiration and administer glucagon as needed.
Prevention and Management Recommendations
- Regular monitoring of blood glucose and ketone levels.
- Control of blood pressure and lipid levels to prevent complications.
- Frequent visits to healthcare providers for routine eye exams to monitor for retinopathy and other complications.
- Education on recognizing hypoglycemia symptoms and effective baked countermeasures.
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Description
Test your knowledge on kidney function recovery stages and diuresis processes. This quiz explores the phases of recovery, including variations with or without diuretics, duration, and the risk stages as indicated by blood creatinine levels. Brush up on your understanding of nephrology topics and their implications.