Kidney Function Assessment Quiz

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Questions and Answers

Which of the following is the most common cause of glomerulonephritis?

  • IgA nephropathy (correct)
  • Focal segmental glomerulosclerosis
  • Interstitial nephritis
  • Membranous glomerulopathy

Which of the following is the most common cause of acute tubular necrosis?

  • Toxins
  • Inflammation
  • Ischemia (correct)
  • Obstruction

Which of the following is the most common cause of interstitial nephritis?

  • Autoimmune disorders
  • Malignancy
  • Drugs (correct)
  • Infections

Which of the following is the most characteristic feature of membranous glomerulopathy?

<p>Subepithelial immune deposits (A)</p> Signup and view all the answers

Which of the following is the most common cause of focal segmental glomerulosclerosis?

<p>Obesity (B)</p> Signup and view all the answers

Which of the following is the primary function of the glomerulus?

<p>Filtration (D)</p> Signup and view all the answers

Which of the following cell types is responsible for the structural integrity of the glomerular basement membrane?

<p>Podocytes (A)</p> Signup and view all the answers

Which of the following is the most common cause of acute tubular necrosis in the setting of acute kidney injury?

<p>Sepsis (B)</p> Signup and view all the answers

Which of the following is a common cause of acute tubular necrosis?

<p>Exposure to nephrotoxic agents (C)</p> Signup and view all the answers

What is the defining histological feature of focal segmental glomerulosclerosis?

<p>Segmental scarring and obliteration of the glomerular tuft (B)</p> Signup and view all the answers

Which of the following is a risk factor for the development of membranous glomerulopathy?

<p>Autoimmune disorders (B)</p> Signup and view all the answers

Which of the following is a common cause of interstitial nephritis?

<p>Acute pyelonephritis (C)</p> Signup and view all the answers

Which of the following structures is responsible for the filtration of blood in the kidney?

<p>Glomeruli (D)</p> Signup and view all the answers

Which of the following is a key function of the renal tubules?

<p>Reabsorption and secretion of substances (C)</p> Signup and view all the answers

What is the main function of the renal cortex?

<p>Filtration of blood (A)</p> Signup and view all the answers

Which of the following is a characteristic of the renal medulla?

<p>Responsible for urine concentration (C)</p> Signup and view all the answers

What is the pathophysiology of Focal Segmental Glomerulosclerosis?

<p>Circulating factor causing protein leak (D)</p> Signup and view all the answers

Which age group is commonly affected by Minimal Change Nephropathy?

<p>Children and young men (C)</p> Signup and view all the answers

What treatment is typically used for Membranous Glomerulopathy?

<p>Steroids and cyclophosphamide (A)</p> Signup and view all the answers

What is a characteristic presentation of Membranous Glomerulopathy?

<p>Massive proteinuria (C)</p> Signup and view all the answers

What is a common association with Focal Segmental Glomerulosclerosis?

<p>Minimal change disease (D)</p> Signup and view all the answers

Which factor contributes to the progression of Focal Segmental Glomerulosclerosis to ESKD?

<p>Focal to global sclerosis (D)</p> Signup and view all the answers

Which condition is most commonly drug-related and may present with fever, arthralgia, and rash?

<p>Interstitial nephritis (B)</p> Signup and view all the answers

What type of kidney injury is characterized by distinct phases that can overlap, such as oliguric and polyuric phases?

<p>Acute tubular necrosis (D)</p> Signup and view all the answers

Which kidney condition is associated with wedge-shaped areas of inflammation in the renal cortex that can lead to kidney injury?

<p>Pyelonephritis (A)</p> Signup and view all the answers

Which type of acute kidney injury is defined by more than just pre-renal causes, affecting the kidneys through toxins and microvascular factors?

<p>Sepsis-induced kidney injury (A)</p> Signup and view all the answers

Which of the following kidney conditions is likely to respond to steroids and usually has no long-term complications?

<p>Interstitial nephritis (C)</p> Signup and view all the answers

What type of kidney injury is broadly divided into ischemic and inflammatory/toxin-induced categories?

<p>Acute tubular necrosis (D)</p> Signup and view all the answers

Which condition presents with 40% of cases showing a presentation similar to nephrotic syndrome?

<p>Focal segmental glomerulosclerosis (B)</p> Signup and view all the answers

Which of the following is the primary cause of acute tubular necrosis?

<p>Ischemic injury due to hypoperfusion (B)</p> Signup and view all the answers

In focal segmental glomerulosclerosis (FSGS), which part of the glomerulus is primarily affected?

<p>Podocytes (B)</p> Signup and view all the answers

Which of the following is the primary pathological feature of membranous glomerulopathy?

<p>Deposition of immune complexes in the subepithelial space (B)</p> Signup and view all the answers

Which part of the nephron is primarily affected in acute interstitial nephritis?

<p>Renal interstitium (A)</p> Signup and view all the answers

What is the primary function of the glomerulus in the kidney?

<p>Filtration of blood (C)</p> Signup and view all the answers

Which part of the nephron is responsible for the reabsorption of water and solutes?

<p>Proximal convoluted tubule (C)</p> Signup and view all the answers

What is the primary function of the loop of Henle in the nephron?

<p>Concentration of urine (A)</p> Signup and view all the answers

Which part of the nephron is responsible for the final regulation of urine composition?

<p>Distal convoluted tubule and collecting duct (B)</p> Signup and view all the answers

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