Jaundice Differential Diagnosis Quiz

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IllustriousPythagoras
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21 Questions

Which class of jaundice is characterized by disorders of bilirubin conjugation, disorders of bilirubin transport, and hepatocellular injury or destruction?

Hepatic

What is the most common cause of post-hepatic jaundice?

Cholestasis

In which class of jaundice does the patient manifest hyperbilirubinemia with bilirubinuria and dark urine?

Post hepatic

What results in clay-colored stool due to lack of bile?

Cholestasis

Which condition leads to increased levels of conjugated bilirubin, urinary bilirubin, ALP, GGT, total bilirubin, and unconjugated bilirubin?

Cholestasis

Which class of jaundice has abnormality outside the liver but normal function inside the liver?

Prehepatic

What is the principal pigment in bile?

Bilirubin

Which bile acids are most common in humans?

Cholic acid and chenodeoxycholic acid

What liver disorder results from mutations in the gene encoding UDP glucuronyl transferase?

Gilbert’s syndrome

Which syndrome presents with a buildup of unconjugated bilirubin in hepatocytes and serum?

Crigler-Najjar syndrome

What liver function plays a role as a gatekeeper between the circulation and absorbed substances?

Detoxification & Drug Metabolism

Which liver process converts insoluble lipids to soluble forms?

Lipid metabolism

Which liver dysfunction is characterized by scar tissue replacing normal healthy liver tissue?

Cirrhosis

Which liver disorder is typically found mostly in children and is often preceded by a viral syndrome?

Reye's Syndrome

What is the primary factor that leads to the formation of toxins in Alcoholic Liver Disease?

Alcohol breakdown

Which liver dysfunction is often associated with profuse vomiting and neurological impairment?

Reye's Syndrome

In which stage of Alcoholic Liver Disease do patients show moderate elevations of AST, ALT, and GGT along with decreased albumin and prolonged PT?

Alcoholic Hepatitis

Which virus causes hepatitis with an incubation period of 2-6 weeks and is primarily transmitted through the fecal-oral route?

Hepatitis A

What accounts for a significant portion of acute liver failure due to its impact on drug metabolism?

Drug and Alcohol Disorders

Which stage of Alcoholic Liver Disease shows the mildest form and has elevations of AST, ALT, GGT, with complete recovery possible if the causative agent is removed?

Alcoholic Fatty Liver

What symptom is common in both Hepatitis and Alcoholic Liver Disease?

Prolonged PT

Test your knowledge on differentiating pre-hepatic and post-hepatic jaundice based on specific clinical presentations and lab results. Identify key markers such as elevated alkaline phosphatase and bile salts, along with symptoms like itching and hypercholesterolemia.

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