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Questions and Answers
Which virus is non-hepatotropic?
Which virus is non-hepatotropic?
- Hepatitis C virus
- Yellow fever virus (correct)
- Hepatitis B virus
- Hepatitis A virus
Which condition is associated with pregnancy?
Which condition is associated with pregnancy?
- Acute fatty liver of pregnancy (correct)
- Wilson disease
- Hepatic sinusoidal obstruction syndrome
- Autoimmune hepatitis
During which phase of acute viral hepatitis do viral titers peak?
During which phase of acute viral hepatitis do viral titers peak?
- Recovery
- Preicteric
- Incubation
- Icteric (correct)
Which virus is associated with Hepatitis D?
Which virus is associated with Hepatitis D?
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Which symptom is uncommon in the preicteric phase of acute viral hepatitis?
Which symptom is uncommon in the preicteric phase of acute viral hepatitis?
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Study Notes
Acute Hepatitis
- Defined as a syndrome leading to liver necro-inflammation and elevated liver function tests for less than 6 months.
Acute Liver Failure (ALF)
- Characterized by rapid decline in hepatic function, evident through jaundice, coagulopathy (INR >1.5), and hepatic encephalopathy (HE).
- Occurs in patients without prior liver disease.
- Classified based on the time from jaundice onset to HE development:
- Hyperacute: HE develops within 7 days.
- Acute: HE occurs between 8 and 28 days.
- Subacute: HE manifests between 29 days and 12 weeks.
Causes of Acute Hepatitis
- Infectious Causes:
- Viral: Hepatitis A, B, C, D, and E.
- Bacterial:
- Gram-negative bacteria associated with acute hepatitis:
- Typhoid fever (caused by Salmonella typhi).
- Tularemia (caused by Francisella tularensis).
- Septicemia.
- Rickettsial infections, such as Typhus.
- Spirochete infections, including Weil's disease (caused by Leptospira) and Relapsing fever (caused by Borrelia).
- Q fever (caused by Coxiella burnetii).
- Mycoplasma infections.
- Gram-negative bacteria associated with acute hepatitis:
- Parasitic: Toxoplasma infection.
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