15 Questions
What is the significance of examining the sclerae for detecting slight increases in serum bilirubin level?
Sclerae have a high elastin content, making them particularly sensitive to bilirubin deposition
What serum bilirubin level does the presence of scleral icterus indicate?
At least 51 µmol/L (3 mg/dL)
What can make it more difficult to detect scleral icterus during physical examination?
Fluorescent lighting in the examining room
What causes green coloration of the skin in longstanding cases of jaundice?
Oxidation of bilirubin to biliverdin
What is the differential diagnosis for yellowing of the skin, as mentioned in the text?
Jaundice, Carotenoderma, Use of the drug quinacrine, Excessive exposure to phenols
Which statement best describes neoplasia?
It is uncontrolled growth of cells not under physiologic control
What is a distinguishing feature of benign tumors?
Slow growth and lack of invasion
What differentiates malignant tumors from benign tumors?
Higher rate of proliferation and potential for invasion
What characterizes a benign tumor in terms of resemblance to normal cells?
It looks a lot like the tissue of normal cells from which it originated (well differentiated)
What is a distinguishing feature of malignant tumors?
Potential to invade and destroy adjacent structures
Which characteristic is common to all neoplasms?
Uncontrolled growth of cells
What distinguishes benign tumors from malignant tumors in terms of growth rate?
Slow growth
What is a distinguishing feature of benign tumors in relation to invasion?
Lack of invasion
What is a characteristic of malignant tumors in terms of resemblance to normal cells?
Less differentiated appearance
What is a distinguishing feature of neoplasia in relation to clonality?
All neoplasms are monoclonal
Learn about jaundice, a yellowish discoloration of tissue caused by the deposition of bilirubin. This quiz explores the relationship between serum hyperbilirubinemia, liver disease, and hemolytic disorders, and explains how to estimate serum bilirubin elevation through physical examination.
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