24 Questions
What is the purpose of swabbing or spraying needle-penetration closures on vials?
To disinfect the surface
What percentage of air particles (03 mm or larger) are removed by High-efficiency particulate air (HEPA) filters?
99.97%
What should be done to the working surface in the BSC?
Wiped down with 70% ethanol and left to dry
What direction should coughing and talking be directed when working in a Laminar Air Flow Hood?
Away from the hood
What is the purpose of a quality check of the product?
To check for container integrity and leaks
What should be done to equipment before placing them in the BSC?
Disinfected
What should be placed in front of the pharmacist for verification?
The product, containers, and devices used, and the label
What type of filter is mentioned in the content?
Membrane filter and filter needle
Why is it ideal to have only one person in the preparation area at a time?
To minimize the risk of contamination
What should be done to the rubber surfaces and neck of ampoules before use?
Disinfected with 70% rubbing alcohol
Why should needles be attached to syringes before ampoule tops are removed?
To prevent contamination of the sterile area
What should be done to solutions from ampoules to remove contaminants?
Filtered
What should be done to ensure complete dissolution of the drug with the appropriate diluents?
Mixing carefully
Why should needle entry into vials with rubber stoppers be done cautiously?
To avoid creating rubber core particles
What should be done to the materials used in the preparation process?
Remain in the assembly tray for checking
What should the responsible person verify during end-product verification?
The correct ingredients, quantities, containers, and reservoirs
What should be removed from hands, fingers, and wrists when preparing IV admixtures?
All jewelry
Why should personnel scrub their hands and forearms with antimicrobial skin cleanser?
At the beginning of each aseptic compounding process
What should be avoided during aseptic preparation?
All of the above
Why should containers and supplies be cleaned?
If dust or dirt is visually present
What should be checked before preparing sterile products?
All of the above
What should be done with defective products?
Report them to the head of pharmacy
Why should nonessential materials be removed from the preparation area?
To prevent contamination
What should be disinfected before being used in sterile product preparation?
Surfaces of ampoules, vials, and container closures
Study Notes
IV Admixture Preparation
- Use of a second container (mini bottle/bag) with already hanging IV fluid and joining them by using a Ύ" tube at the bottom.
Aseptic Technique
- Remove jewelry from hands, fingers, and wrists before preparing IV admixtures.
- Scrub hands and forearms with antimicrobial skin cleanser at the beginning of each aseptic compounding process.
- Wear appropriate attire and avoid eating, drinking, coughing, sneezing, and smoking in the preparation area.
- Gather all drugs and supplies before initiating the preparation process.
- Clean containers and supplies if dust or dirt is visually present.
- Check containers for cracks, punctures, and clarity before preparation.
- Inspect each ingredient and container for defects, expiration date, and product integrity before use.
Preparation Process
- Disinfect surfaces of ampoules, vials, and container closures with 70% isopropyl alcohol before use.
- Minimize the number of personnel preparing sterile products in the preparation area.
- Perform mathematical calculations before initiating the preparation process.
- Avoid touch contamination of sterile needles, syringe parts, and other critical sites.
- Filter solutions from ampoules to remove glass particles.
- Mix solutions of reconstituted powders carefully to ensure complete dissolution.
Verification and Labeling
- Check the identity and verify the amounts of ingredients in sterile preparations against the original prescription.
- Verify that the product was compounded accurately with respect to the use of correct ingredients, quantities, containers, and reservoirs.
- The product label should include all necessary information for appropriate administration and the initials of the persons who prepared and checked the product.
Laminar Air Flow Hood
- LAFH provides parallel layers of clean air that moves across a given area with uniform velocity and creating a minimum amount of turbulence.
- HEPA filters remove 99.97% of all air particles (0.3 mm or larger).
- Two types of LAFH: Horizontal and Vertical.
Working in the Laminar Air Flow Hood
- Coughing and talking should be directed away from the hood.
- Wipe down the working surface in the BSC with 70% ethanol and leave to dry.
- Disinfect any equipment before placing them into the BSC.
- Swab or spray needle-penetration closures on vials, injection ports, and other materials.
- Keep the working area in the BSC organized and avoid clutter.
- Be careful not to block the air vents at the back and front of the BSC.
- Work well inside the BSC and not directly above the front air vents.
- Keep your nose and mouth away from the window opening.
This quiz assesses knowledge of IV admixture preparation, including the use of second containers and aseptic technique. It covers important guidelines for personnel, such as removing jewelry and wearing appropriate attire.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
