Geriatrics E2 Fien

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Questions and Answers

Which imaging modality is generally considered safest for initial evaluation in a patient with acute kidney injury and rising BUN/creatinine?

  • MRI with gadolinium
  • CT scan with intravenous contrast
  • Renal ultrasound (correct)
  • Nuclear medicine renal scan

A 70-year-old male presents with hematuria. What is the most appropriate next step in management?

  • Repeat urinalysis in 6 weeks
  • Perform cystoscopy (correct)
  • Order a CT scan of the abdomen and pelvis
  • Prescribe antibiotics for presumed UTI

In an elderly male, what is the most probable cause of complete loss of urine production (anuria)?

  • Acute tubular necrosis from nephrotoxic medications
  • Post-renal obstruction due to benign prostatic hyperplasia (correct)
  • Pre-renal azotemia due to dehydration
  • Glomerulonephritis

What is the most common cause of end-stage renal disease (ESRD) seen in elderly patients in the United States?

<p>Diabetic nephropathy (A)</p> Signup and view all the answers

A 70-year-old male with an A1C of 5.9% and fasting blood glucose of 85 mg/dL presents with erectile dysfunction. Which of the following is the most appropriate first-line treatment?

<p>Phosphodiesterase type 5 (PDE5) inhibitors (A)</p> Signup and view all the answers

An elderly patient presents with elevated BUN and creatinine, is volume depleted, and febrile. What is the most common underlying etiology for these findings?

<p>Pre-renal azotemia due to dehydration and sepsis (B)</p> Signup and view all the answers

Which factor is LEAST likely to guide treatment decisions in an elderly male with symptomatic benign prostatic hyperplasia (BPH)?

<p>Prostate-Specific Antigen (PSA) level (B)</p> Signup and view all the answers

Which of the following is a common presentation of benign prostatic hyperplasia (BPH) in an elderly male?

<p>Progressive nocturia, hesitancy, and weak urinary stream (C)</p> Signup and view all the answers

Which of the following medications is LEAST likely to contribute to hyperkalemia in elderly patients?

<p>Furosemide (D)</p> Signup and view all the answers

What is the most common cause of hypernatremia in an elderly nursing home patient?

<p>Decreased water intake due to impaired thirst or access (D)</p> Signup and view all the answers

What is the recommended minimum duration between dose adjustments when initiating levothyroxine therapy for hypothyroidism in an elderly patient?

<p>6-8 weeks (A)</p> Signup and view all the answers

What is the most common underlying cause of hypothyroidism in the elderly population?

<p>Autoimmune thyroiditis (Hashimoto's disease) (C)</p> Signup and view all the answers

Which of the following clinical presentations is MOST characteristic of hyperglycemic hyperosmolar state (HHS) in an elderly patient?

<p>Serum glucose level exceeding 600 mg/dL with minimal ketosis (B)</p> Signup and view all the answers

What is the most consistently proven efficacious approach to prevent or delay the progression of diabetic retinopathy in elderly patients with diabetes mellitus?

<p>Improved control of blood glucose concentrations (D)</p> Signup and view all the answers

For a healthy elderly patient with diabetes mellitus and an extended life expectancy, what is the generally recommended Hemoglobin A1c (HbA1c) target to minimize the risk of microvascular complications according to the American Diabetes Association (ADA)?

<p>HbA1c &lt; 7.0% (A)</p> Signup and view all the answers

In elderly patients, what is a common atypical presentation of primary hyperthyroidism that can make it challenging to diagnose?

<p>Predominant symptoms of fatigue, weight loss, and new onset atrial fibrillation (B)</p> Signup and view all the answers

Which set of laboratory findings is MOST indicative of primary hyperthyroidism?

<p>Suppressed TSH and elevated free T4 (C)</p> Signup and view all the answers

What gastrointestinal (GI) abnormality is a recognized complication of long-standing type 2 diabetes mellitus, often resulting from autonomic neuropathy?

<p>Diabetic gastroparesis causing delayed gastric emptying (A)</p> Signup and view all the answers

What is the MOST appropriate initial step in managing levothyroxine therapy for a newly diagnosed elderly patient with hypothyroidism, particularly one with a history of coronary artery disease (CAD)?

<p>Start with a low dose of levothyroxine (12.5-25 mcg daily) and gradually increase. (B)</p> Signup and view all the answers

An 80-year-old female with a history of heart failure and type 2 diabetes mellitus presents with new-onset atrial fibrillation and unintentional weight loss. Laboratory tests reveal a suppressed TSH and elevated free T4. Which of the following is the MOST appropriate INITIAL management step, considering her comorbidities and acute presentation?

<p>Initiate propylthiouracil (PTU) and a beta-blocker for symptom control and thyroid hormone reduction, while carefully managing heart failure and diabetes. (B)</p> Signup and view all the answers

Which of the following auscultation findings is MOST suggestive of aortic regurgitation in an elderly patient?

<p>A blowing, high-pitched diastolic murmur heard best at the left sternal border. (B)</p> Signup and view all the answers

In patients over 65 years of age, which condition is the MOST frequent admitting diagnosis in hospitals covered by Medicare?

<p>Heart Failure (HF) (A)</p> Signup and view all the answers

Which physical exam finding is MOST characteristic of chronic venous insufficiency in an elderly patient?

<p>Shiny, atrophic skin with a reddish-cyanotic hue around the ankle. (D)</p> Signup and view all the answers

Which of the following is considered a normal physiological change in the aging heart?

<p>Increased vascular stiffness. (A)</p> Signup and view all the answers

Which cardiovascular physical exam finding is LEAST likely to be considered a normal age-related change in an elderly patient?

<p>Prominent S3 heart sound. (C)</p> Signup and view all the answers

According to the provided material, what is the leading cause of death worldwide in older adults?

<p>Heart Disease (C)</p> Signup and view all the answers

For an elderly patient with hypertension and diabetes mellitus, which class of medications is generally recommended as part of the first-line therapy, based on general hypertension management principles?

<p>Diuretics (C)</p> Signup and view all the answers

Which of the following is the MOST commonly reported symptom of atrial fibrillation (AF) in the elderly?

<p>Palpitations (C)</p> Signup and view all the answers

What is the MOST prevalent valvular heart disease observed in the geriatric population, based on the provided text?

<p>Calcific Aortic Stenosis (B)</p> Signup and view all the answers

An 85-year-old patient presents with new onset exertional dyspnea and fatigue. On physical examination, a systolic ejection murmur is noted, and an S4 heart sound is auscultated. Which underlying cardiovascular condition is MOST consistent with these findings, considering the patient's age and presentation?

<p>Calcific aortic stenosis related to age-related degeneration (D)</p> Signup and view all the answers

Flashcards

AKI imaging with rising BUN/Creatinine

Renal ultrasound is safest to measure renal size and rule out obstruction without contrast exposure.

Hematuria evaluation in elderly males

Diagnostic work-up includes Urine cytology (evaluate hematuria) and cystoscopy

Complete loss of urine production cause

Acute urinary retention may result from prolonged attempts to retain urine, immobilization, or medications.

Common cause of ESRD in elderly

The most common cause of end-stage renal disease (ESRD) is diabetic nephropathy

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ED treatment in a healthy 70-year-old

First line medications such as sildenafil (Viagra) can be used.

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Common cause of increased BUN/Creatinine

Volume depletion is the most common cause for elevation of BUN/Creatinine in febrile elderly patients

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Factors guiding BPH treatment

Factors such as symptom severity, prostate size, and patient preferences should be considered when guides treatment in BPH.

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BPH presentation in elderly males

BPH presents with urinary frequency, urgency, nocturia, decreased stream, hesitancy, intermittency.

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Hyperkalemia in elderly patients

The primary etiology of Hyperkalemia in older adults is medication induced.

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Hypernatremia in nursing home patients

Decreased water intake due to mental or physical impairment are common causes which can lead to hypernatremia

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Thyroid dose adjustment interval

Adjust dose every 6-8 weeks based on TSH levels.

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Most common hypothyroidism cause

Autoimmune thyroiditis (Hashimoto's)

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Presentation of HHS

Marked hyperglycemia (> 600 mg/dL), hyperosmolarity, severe volume depletion, altered mental status

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Efficacious prevention of retinopathy

Improved control of blood glucose concentrations.

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Optimal Hgb A1C level

Less than 7% is associated with decreased risk of neuropathy, retinopathy, renal, and CVD.

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Common hyperparathyroidism presentation

Asymptomatic hypercalcemia.

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Hyperthyroidism lab findings

Decreased TSH. Elevated T4.

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Long-standing DMT2 GI issue

Diabetic Gastroparesis.

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Hypothyroidism therapy in elderly

Start low (12.5-25 mcg/day) and increase slowly.

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Aortic Regurgitation (AR) PE Findings

Bounding pulses, wide pulse pressure, early diastolic murmur. Possible angina, palpitations, or heart failure.

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Most Common Medicare Admission

Heart Failure. Accounts for a large percentage of Medicare hospitalizations.

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Chronic Venous Insufficiency Signs

Edema, skin changes (atrophic, shiny, dry, reddish/cyanotic), limb pain with prolonged standing .

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Aging Heart: Physiologic Changes

Decreased response to stress, increased stiffness, altered diastolic relaxation, preserved systolic function.

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Elderly Cardiovascular Exam Findings

Softer heart sounds, splitting of S2, possible systolic ejection murmur (SEM), S4 often present, possible carotid bruit.

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Geriatric Mortality: Top Cause

Cardiovascular Disease (CAD, MI, and Stroke).

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HTN + DM: Preferred Treatment

ACE inhibitors or ARBs are preferred due to their renal protective effects.

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AF Presentation in Elderly

May present atypically with fatigue, dyspnea, dizziness, syncope, confusion, or heart failure instead of palpitations.

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Valvular Disease: Most Common

Calcific Aortic Stenosis (AS)

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Study Notes

PE findings in an elderly patient with Aortic Regurgitation.

  • Aortic Regurgitation is usually asymptomatic typically until the 4th or 5th decade of life.
  • The patient may experience dyspnea on exertion (DOE), orthopnea, and paroxysmal nocturnal dyspnea (PND).
  • Significant cardiomegaly and LV dysfunction may occur.
  • Other findings can include angina, which develops later and often during nighttime.
  • Palpitations and head pounding, are common especially in the supine position, as the heart pounds against the chest wall.

Most frequent hospital admitting diagnosis in a Medicare age patient.

  • Heart disease is the most common cause for hospitalization in older adults.
  • Heart failure is documented as the most common cause of hospitalization in the Medicare age group.

Physical Exam findings in a patient with chronic venous insufficiency.

  • Edema usually develops slowly and initially involves only the ankle.
  • The skin can be dry, shiny, and atrophic with a reddish, cyanotic hue when dependent, which causes hyperpigmentation.
  • The limb is warm, not cool, unlike arterial disease.
  • Limb pain occurs with prolonged standing.
  • Chronic edema may result in ulcer formation above the medial malleolus
  • Venous ulceration is noted in the "gaiter" region of the legs, located circumferentially around the lower leg from approximately mid calf to just below the medial and lateral malleoli.

Normal physiologic changes that occur in the aging heart.

  • Physiological changes of the cardiovascular system in aging may modify the presentation of heart disease.
  • Peak physiological function occurs at 20-30 years of age.
  • Myocardial reserve mechanisms maintain normal function causing older persons to be more vulnerable to developing dysfunction when disease is superimposed.
  • Heart rate (HR) response to exercise decreases in older adults due to diminished beta-adrenergic responsiveness.
  • Cardiac output (CO) is maintained by increasing cardiac volumes (end-diastolic and end-systolic volumes).
  • Older persons depend more on atrial contraction for LV filling potentially leading to heart failure if atrial fibrillation (AF) occurs.
  • Heart failure (HF) may occur in the absence of systolic dysfunction or valvular disease.
  • Maximal HR response declines on stress testing and is attenuated at all levels of exercise.
  • Vascular stiffness increases leading to a rise in afterload (SBP).
  • Altered diastolic compliance leads to changes in the relaxation phase of the cardiac cycle, causing an increase in diastolic LV wall thickness
  • Systolic function is preserved.
  • Older patients do not respond the same as middle aged or younger adults to therapies.

CVS physical exam findings present in the elderly population.

  • Softer S1 and S2 sounds occur due to increased distance between the heart and chest wall with age.
  • Splitting of S2 is detected in 30-40% of the population and wide splitting increasing with inspiration suggests RBBB.
  • A systolic ejection murmur (SEM) is detected in 50% but is short in duration, Grade 1-2, and does not radiate.
  • An S4 heart sound is often present due to reduced LV diastolic compliance.
  • Auscultation of a carotid bruit suggests but does not prove partial arterial obstruction.
  • Hearing a carotid bruit is unlikely if stenosis is < 40% and may not be heard if stenosis is >90% because of low flow.

Most common cause of mortality in geriatric aged patients.

  • Heart disease is a leading cause of death worldwide in older adults
  • CAD causes 80% of deaths in adults > 65 years old.

Treatment of choice for a hypertensive patient with DM.

  • Treatment, including those who with isolated systolic HTN, should follow same principles outlined for general care of HTN.
  • Diuretics, diuretics plus beta blockers, and CCBs are often used as first-line therapy.
  • Use lower initial drug doses to avoid symptoms, utilizing standard doses and multiple drugs to reach BP targets.
  • There is no specific drug class that is contraindicated in older adults.

Presentation of AF in the elderly population.

  • AF occurs in 5% to 10% of ambulatory older adults and more frequently in hospitalized patients.
  • Associated with underlying heart disease but the causes are the same as in younger individuals.
  • Symptoms include palpitations
  • Patients can be asymptomatic, while others have fatigue, dyspnea, chest pain, hypotension, syncope, confusion, dizziness, or CHF.
  • Characterized as paroxysmal, persistent, long-standing persistent, or permanent
  • It is important to determine its underlying cause as well as defining associated cardiac and extracardiac disease and assessing thromboembolic risk.

Most common valvular heart disease present in the geriatric population.

  • Presence of clinically significant aortic stenosis (AS) increases with age.
  • Aortic and mitral valve (MV) calcification is common among older adults

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