Isoniazid and Rifampin Adverse Effects Quiz
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Questions and Answers

Which antitubercular drug is associated with arthralgia in 40% of patients?

  • Isoniazid
  • Rifampin
  • Ethambutol
  • Pyrazinamide (correct)

What is the most common adverse effect of rifampin?

  • Gastrointestinal issues
  • Discoloration of body fluids (correct)
  • Immune-mediated reactions
  • Hepatotoxicity

Which antitubercular drug has a preventive measure for neurotoxicity involving the administration of pyridoxine?

  • Pyrazinamide
  • Isoniazid (correct)
  • Rifampin
  • Ethambutol

Which antitubercular drug is associated with optic neuritis as an adverse effect?

<p>Ethambutol (C)</p> Signup and view all the answers

Which antitubercular drug is known for its nephrotoxicity and ototoxicity?

<p>Streptomycin (A)</p> Signup and view all the answers

Which antitubercular drug combination has the highest risk of hepatotoxicity?

<p>Rifampin + Pyrazinamide (C)</p> Signup and view all the answers

Which drug should not be added as a single agent to a failing antitubercular regimen?

<p>Pyrazinamide (C)</p> Signup and view all the answers

Which antitubercular drug is not associated with hepatotoxicity?

<p>Ethambutol (A)</p> Signup and view all the answers

What are the common adverse effects of isoniazid?

<p>Neurotoxicity and hepatotoxicity are common adverse effects of isoniazid.</p> Signup and view all the answers

What is the most common adverse effect of ethambutol?

<p>Optic neuritis is the most common adverse effect of ethambutol.</p> Signup and view all the answers

Which antitubercular drug is associated with red/orange discoloration of body fluids?

<p>Rifampin is associated with red/orange discoloration of body fluids.</p> Signup and view all the answers

What is the preventive measure for neurotoxicity associated with isoniazid?

<p>Neurotoxicity associated with isoniazid can be prevented with the administration of pyridoxine.</p> Signup and view all the answers

What are the potential adverse effects of pyrazinamide?

<p>Arthralgia and flushing reaction are potential adverse effects of pyrazinamide.</p> Signup and view all the answers

Which antitubercular drug is associated with nephrotoxicity and ototoxicity?

<p>Streptomycin is associated with nephrotoxicity and ototoxicity.</p> Signup and view all the answers

What is the basic principle of antitubercular therapy?

<p>Multiple drugs are utilized to prevent the emergence of resistance.</p> Signup and view all the answers

Why is adherence to therapy crucial for a successful outcome in antitubercular treatment?

<p>Adherence to therapy is crucial for a successful outcome in antitubercular treatment to prevent the emergence of resistance.</p> Signup and view all the answers

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