Isoniazid and Rifampin Adverse Effects Quiz

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16 Questions

Which antitubercular drug is associated with arthralgia in 40% of patients?

Pyrazinamide

What is the most common adverse effect of rifampin?

Discoloration of body fluids

Which antitubercular drug has a preventive measure for neurotoxicity involving the administration of pyridoxine?

Isoniazid

Which antitubercular drug is associated with optic neuritis as an adverse effect?

Ethambutol

Which antitubercular drug is known for its nephrotoxicity and ototoxicity?

Streptomycin

Which antitubercular drug combination has the highest risk of hepatotoxicity?

Rifampin + Pyrazinamide

Which drug should not be added as a single agent to a failing antitubercular regimen?

Pyrazinamide

Which antitubercular drug is not associated with hepatotoxicity?

Ethambutol

What are the common adverse effects of isoniazid?

Neurotoxicity and hepatotoxicity are common adverse effects of isoniazid.

What is the most common adverse effect of ethambutol?

Optic neuritis is the most common adverse effect of ethambutol.

Which antitubercular drug is associated with red/orange discoloration of body fluids?

Rifampin is associated with red/orange discoloration of body fluids.

What is the preventive measure for neurotoxicity associated with isoniazid?

Neurotoxicity associated with isoniazid can be prevented with the administration of pyridoxine.

What are the potential adverse effects of pyrazinamide?

Arthralgia and flushing reaction are potential adverse effects of pyrazinamide.

Which antitubercular drug is associated with nephrotoxicity and ototoxicity?

Streptomycin is associated with nephrotoxicity and ototoxicity.

What is the basic principle of antitubercular therapy?

Multiple drugs are utilized to prevent the emergence of resistance.

Why is adherence to therapy crucial for a successful outcome in antitubercular treatment?

Adherence to therapy is crucial for a successful outcome in antitubercular treatment to prevent the emergence of resistance.

Test your knowledge of adverse effects associated with isoniazid (INH) and rifampin (RIF) by taking this quiz. Learn about neurotoxicity, peripheral neuropathy, and hepatotoxicity, along with prevention and risk factors for these adverse effects.

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