Ischemic Heart Disease Overview

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Questions and Answers

What is the primary initial management strategy for stable angina?

  • Immediate surgical intervention
  • Emergency management using MONA-B protocol
  • Only pharmacological therapy without lifestyle changes
  • Lifestyle changes and pharmacological therapy (correct)

Which of the following are considered advanced imaging techniques for cardiac assessment?

  • Stress echocardiography (correct)
  • Coronary CT angiography (correct)
  • Electrocardiogram (ECG)
  • Chest X-ray

What does the MONA-B emergency management protocol include?

  • Morphine, Oxygen, Nitroglycerin, Aspirin, and Beta-blockers (correct)
  • Morphine, Antiplatelets, Nitrates, and Aspirin
  • Morphine, Oxygen, Nitrates, Antidepressants, and Beta-blockers
  • Morphine, Oxygen, Nitrates, and Beta-blockers

Which complication is NOT typically associated with ischemic heart disease (IHD)?

<p>Kidney stones (A)</p> Signup and view all the answers

What is a key component of post-ACS care and secondary prevention?

<p>Continuation of lifestyle changes and anti-anginal therapy (B)</p> Signup and view all the answers

What term is used to describe chronic coronary syndromes including stable angina?

<p>Ischemic Heart Disease (D)</p> Signup and view all the answers

Which factor is NOT typically recognized as a risk factor for Ischemic Heart Disease?

<p>High physical activity level (A)</p> Signup and view all the answers

Which of the following correctly identifies a clinical presentation of unstable angina?

<p>New onset or worsening angina (C)</p> Signup and view all the answers

Which diagnostic test is critical for evaluating Ischemic Heart Disease and often shows key findings?

<p>Electrocardiogram (ECG) (C)</p> Signup and view all the answers

What is a common pharmacological management option for patients with IHD?

<p>Antiplatelets (D)</p> Signup and view all the answers

Which statement about the pathophysiology of IHD is incorrect?

<p>Inflammation plays no significant role. (B)</p> Signup and view all the answers

Which clinical feature is characteristic of stable angina?

<p>Relief with rest or nitroglycerin (D)</p> Signup and view all the answers

Which management strategy is considered an invasive procedure for IHD?

<p>Coronary artery bypass grafting (CABG) (B)</p> Signup and view all the answers

Flashcards

Cardiac Biomarkers: Troponins and CK-MB

Troponins are proteins found in heart muscle that are released into the bloodstream when the heart is damaged. CK-MB is another enzyme found in heart muscle that can be elevated in heart attacks.

Stress Testing: What is it for?

Stress testing helps doctors assess the heart's function under stress. It involves exercising or using medication to increase heart rate and blood pressure.

Acute Coronary Syndromes (ACS)

Acute Coronary Syndromes (ACS) occur when there is a sudden blockage in a coronary artery, leading to chest pain, shortness of breath, or other symptoms.

Emergency Treatment for ACS: MONA-B

MONA-B is a mnemonic used to remember the emergency treatment for ACS. It stands for Morphine, Oxygen, Nitrates, Aspirin, and Beta-blockers.

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Reperfusion Strategies: PCI vs Thrombolysis

PCI (percutaneous coronary intervention) involves inserting a catheter into a blocked coronary artery to open it up. Thrombolysis is a medication that dissolves blood clots in the artery.

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Ischemic Heart Disease (IHD)

A condition characterized by reduced blood flow to the heart muscle due to narrowing or blockage of coronary arteries.

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Atherosclerosis

A buildup of fatty plaques inside the arteries, narrowing the passage for blood flow.

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Plaque Rupture & Thrombosis

When a plaque ruptures, triggering a blood clot that further blocks the artery, significantly reducing blood flow.

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Angina

Chest pain that occurs when the heart muscle isn't receiving enough oxygen. This can manifest as tightness, pressure, or squeezing.

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Stable Angina

A stable form of angina characterized by predictable pain with exertion, relieved with rest or medication.

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Unstable Angina

A less predictable form of angina that occurs at rest or with minimal effort, indicating a more severe blockage.

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Myocardial Infarction (MI)

A blockage that causes significant damage to the heart muscle, resulting in cell death.

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Percutaneous Coronary Intervention (PCI)

A procedure that uses a balloon to widen a narrowed or blocked coronary artery, often accompanied by a stent to keep it open.

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Study Notes

Ischemic Heart Disease (IHD)

  • IHD is a condition where the heart's blood supply is reduced, leading to reduced oxygen and impaired function
  • Chronic coronary syndrome (stable angina) and acute coronary syndrome (unstable angina, NSTEMI, STEMI) are subtypes
  • Atherosclerosis, plaque rupture, and thrombosis are key mechanisms causing IHD
  • Risk factors include hypertension, diabetes, smoking, dyslipidemia, and genetic factors
  • Clinical presentations vary depending on the type and severity of IHD
  • Differentiating stable angina, unstable angina, and myocardial infarction (MI) is crucial for timely management
  • Atypical presentations, especially in women and diabetics, require careful consideration
  • Diagnosis employs ECG, cardiac biomarkers, stress testing, and imaging (like angiography)
  • Essential pharmacological management includes antiplatelets, statins, beta-blockers, and nitrates
  • Invasive procedures like PCI (percutaneous coronary intervention) and CABG (coronary artery bypass grafting) are used for severe cases
  • Lifestyle modifications and secondary prevention are vital for long-term management
  • Long-term consequences include potential heart failure, arrhythmias, and recurrent ischemia

Pathophysiology of IHD

  • Atherosclerosis involves the buildup of plaque in the coronary arteries
  • Plaque rupture leads to the exposure of underlying tissues and promotes clot formation (thrombosis)
  • Ischemia results from the demand-supply mismatch, inflammation, and endothelial dysfunction in the heart

Clinical Features of IHD

  • Stable angina presents with predictable chest pain that typically follows exertion and is relieved by rest
  • Unstable angina features new onset or worsening angina, and even at rest
  • NSTEMI (Non-ST-elevation myocardial infarction) and STEMI (ST-elevation myocardial infarction) exhibit distinct clinical presentations and ECG findings
  • Atypical presentations require specific considerations for women, the elderly, or diabetic patients

Diagnostic Workup

  • Recognizing IHD involves a thorough history and physical examination
  • ECG reveals characteristic changes like ST-segment elevation or depression, and T-wave inversion
  • Cardiac biomarkers (troponins and CK-MB) indicate myocardial damage
  • Stress testing evaluates the heart's response to increased demand for blood flow
  • Advanced imaging techniques including coronary CT angiography, stress echocardiography, and MRI provide detailed views of the coronary arteries

Management Strategies

  • Management of stable angina initially involves lifestyle changes and pharmacological therapies
  • Anti-anginals, antiplatelets, and statins are used to manage stable angina symptoms
  • Emergency management of acute coronary syndromes (e.g., unstable angina, NSTEMI, STEMI) employs the MONA-B approach (Morphine, Oxygen, Nitrates, Aspirin, Beta-blockers)
  • Reperfusion therapies like PCI or thrombolysis are used to restore blood flow to the heart
  • Post-ACS (acute coronary syndrome) care emphasizes secondary prevention to reduce the risk of recurring events

Prognosis and Complications

  • Long-term outcomes and potential complications associated with IHD include heart failure, arrhythmias, mechanical complications, and recurrent ischemia
  • Factors contributing to the prognosis include severity, risk factors, and timely interventions

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