Ischemic Heart Disease Overview
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Questions and Answers

Which of the following is an unalterable risk factor for ischemic heart disease?

  • Family history or genetic composition (correct)
  • Hypertension
  • Obesity
  • Smoking
  • What is the primary goal of short-term treatment for effort-induced angina?

  • Prevent coronary heart disease events
  • Lower blood pressure
  • Reduce or prevent anginal symptoms (correct)
  • Extend the patient’s life
  • Which of the following alterable risk factors can increase the likelihood of ischemic heart disease?

  • Age
  • Hyperuricemia (correct)
  • Environmental influences
  • Gender
  • What is the long-term goal of treatment for effort-induced angina?

    <p>Extend the patient’s life</p> Signup and view all the answers

    Which of the following is a secondary intervention for ischemic heart disease?

    <p>Modification of risk factors</p> Signup and view all the answers

    How do β-adrenergic blockers help in the treatment of effort-induced angina?

    <p>By decreasing heart rate, contractility, and blood pressure</p> Signup and view all the answers

    What is the relationship between myocardial blood flow and arteriolar resistance?

    <p>Myocardial blood flow is inversely related to arteriolar resistance</p> Signup and view all the answers

    What is the significance of atherosclerotic lesions occluding R1?

    <p>They increase arteriolar resistance</p> Signup and view all the answers

    What is the clinical presentation of ischemic episodes?

    <p>They are often asymptomatic</p> Signup and view all the answers

    What is the relationship between the severity of stenosis and clinical events such as MI?

    <p>Relatively severe stenosis (&gt;70%) may provoke clinical events such as MI</p> Signup and view all the answers

    What are some precipitating factors for ischemic episodes?

    <p>All of the above</p> Signup and view all the answers

    What is the role of R2 in maintaining coronary blood flow?

    <p>R2 can vasodilate to maintain coronary blood flow</p> Signup and view all the answers

    What is the primary determinant in the occurrence of ischemia in ischemic heart disease?

    <p>Caliber of resistance vessels delivering blood to the myocardium and myocardial oxygen demand</p> Signup and view all the answers

    What does the double product (DP) serve as in the context of ischemic heart disease?

    <p>Indirect estimate of myocardial oxygen demand</p> Signup and view all the answers

    Which of the following is NOT a major determinant of myocardial oxygen demand?

    <p>Intramyocardial wall tension during diastole</p> Signup and view all the answers

    Which of the following is NOT a presentation of ischemic heart disease?

    <p>Congestive heart failure</p> Signup and view all the answers

    Which of the following best describes the relationship between large epicardial vessels and intramyocardial arteries and arterioles in normal circumstances?

    <p>Resistance in R2 is much greater than that in R1</p> Signup and view all the answers

    Which of the following is NOT a potential intervention to alleviate ischemia in ischemic heart disease?

    <p>Increasing intramyocardial wall tension during systole</p> Signup and view all the answers

    Study Notes

    Risk Factors for Coronary Heart Disease (CHD)

    • Ask patients about personal risk factors for CHD, including smoking, hypertension, and diabetes mellitus
    • Obtain family history, including premature CHD, hypertension, lipid disorders, and diabetes mellitus

    Goals of Treatment

    • Short-term goals: reduce or prevent anginal symptoms that limit exercise capability and impair quality of life
    • Long-term goals: prevent CHD events such as myocardial infarction (MI), arrhythmias, and heart failure (HF), and extend the patient's life

    Nonpharmacologic Therapy

    • Primary prevention: modify risk factors to reduce prevalence of IHD
    • Secondary intervention: reduce subsequent morbidity and mortality
    • Risk factors for IHD are additive and can be classified as alterable or unalterable

    Alterable and Unalterable Risk Factors

    • Alterable risk factors: smoking, hypertension, hyperlipidemia, obesity, sedentary lifestyle, hyperuricemia, psychosocial factors, and use of detrimental drugs
    • Unalterable risk factors: gender, age, family history or genetic composition, environmental influences, and diabetes mellitus

    Pharmacologic Therapy

    • β-Adrenergic blockers: decrease heart rate, contractility, and blood pressure, reducing MVo2 and oxygen demand in patients with effort-induced angina
    • Myocardial blood flow is inversely related to arteriolar resistance and directly related to coronary driving pressure

    Clinical Presentation

    • Many ischemic episodes are asymptomatic (silent ischemia)
    • Symptoms may include pressure or burning over the sternum, radiating to the left jaw, shoulder, and arm, and can be precipitated by exercise, cold environment, emotional upset, and other factors
    • Symptoms usually last from 30 seconds to 30 minutes

    Ischemic Heart Disease (IHD)

    • Defined as lack of oxygen and decreased or no blood flow to the myocardium resulting from coronary artery narrowing or obstruction
    • Can present as acute coronary syndrome (ACS), chronic stable exertional angina, ischemia without symptoms, or ischemia due to coronary artery vasospasm (variant or Prinzmetal angina)

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    Description

    Learn about Ischemic Heart Disease (IHD) and its various presentations, including acute coronary syndrome and chronic stable exertional angina. Understand the definition, causes, and symptoms associated with IHD.

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