Introduction to Psychiatry

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Questions and Answers

What does the bio-psycho-social model, central to psychiatry, primarily aim to explain?

  • Social determinants of mental health, undermining biological and psychological influences.
  • The biological basis of all mental illnesses, disregarding psychological and social factors.
  • The superiority of psychological interventions over biological treatments.
  • Human behavior by integrating biological, psychological, and social factors. (correct)

Which statement accurately describes the relationship between the mind and body in psychosomatic medicine?

  • The mind and body have a unidirectional relationship where mental states dictate physical health.
  • The body primarily affects the mind, with minimal impact in the reverse direction.
  • The mind and body have a bidirectional relationship, where each influences the other's state of health. (correct)
  • The mind and body are independent entities that do not significantly influence each other.

What crucial diagnostic step differentiates psychiatric symptoms due to a medical condition from primary psychiatric disorders?

  • Identifying a direct physiological consequence of a medical condition that explains the psychiatric symptoms. (correct)
  • Excluding the possibility of any psychological stressors in the patient's life.
  • Confirming the absence of any past psychiatric history in the patient or their family.
  • Relying solely on the patient's self-reported symptoms without objective measures.

What is an important consideration when a patient presents with new-onset psychiatric symptoms?

<p>A thorough evaluation should be conducted to rule out underlying medical conditions. (D)</p> Signup and view all the answers

Which clinical feature is most suggestive of a medical, rather than a primary psychiatric, origin of mental health symptoms?

<p>Fluctuating levels of consciousness and cognitive abilities. (A)</p> Signup and view all the answers

In a patient presenting with psychiatric symptoms, which historical detail would most strongly suggest an underlying medical etiology?

<p>The recent diagnosis and treatment of a significant endocrine disorder. (D)</p> Signup and view all the answers

When evaluating a patient with suspected delirium, what is the significance of identifying a 'direct physiological consequence' related to their symptoms?

<p>It establishes a clear link between an identified medical condition and the patient's altered mental state. (B)</p> Signup and view all the answers

Which of the following is the most critical initial assessment in differentiating dementia from delirium?

<p>Assessing for fluctuations in attention and awareness. (D)</p> Signup and view all the answers

What clinical feature most strongly suggests a diagnosis of delirium over a primary psychotic disorder?

<p>Acute onset of disorganized thinking with fluctuating levels of consciousness. (C)</p> Signup and view all the answers

Which assessment strategy is most critical in evaluating a patient presenting with acute delirium?

<p>A thorough review of systems, physical examination, and medication reconciliation. (B)</p> Signup and view all the answers

What distinguishes depression caused by a general medical condition from a primary depressive disorder?

<p>Direct pathophysiological consequence of a medical ailment or condition. (A)</p> Signup and view all the answers

A patient being treated for hepatitis C with interferon alpha begins to exhibit symptoms of major depression. What is the most appropriate course of action?

<p>Assess for the severity of depressive symptoms and consider adjusting or discontinuing interferon alpha in consultation with the treating physician. (D)</p> Signup and view all the answers

A patient with no prior psychiatric history develops prominent olfactory hallucinations. What underlying condition should the clinician suspect?

<p>Temporal lobe epilepsy. (C)</p> Signup and view all the answers

What key factor differentiates anxiety disorder due to a general medical condition from primary anxiety disorders?

<p>The direct physiological consequence of a medical condition or treatment. (B)</p> Signup and view all the answers

Which of the following is the MOST critical first step in evaluating a patient presenting with new-onset psychiatric symptoms?

<p>Conducting a thorough medical history, physical examination, and review of systems. (A)</p> Signup and view all the answers

What is a common feature of both delirium and dementia?

<p>Impairment in cognitive function. (C)</p> Signup and view all the answers

A 68-year-old patient with no prior history of mental illness presents with new-onset depression characterized by psychomotor retardation, anhedonia, and significant weight loss. The patient's spouse reports that these symptoms began shortly after the patient was diagnosed with pancreatic cancer. Which of the following is the MOST likely diagnosis?

<p>Depressive disorder due to pancreatic cancer. (A)</p> Signup and view all the answers

What is the defining characteristic of a somatic symptom disorder?

<p>Psychological factors contributing to medical symptoms. (D)</p> Signup and view all the answers

What condition represents a medical complication of psychiatric treatment?

<p>Neuroleptic malignant syndrome. (D)</p> Signup and view all the answers

What is it called when a psychiatric condition co-occurs with a medical issue?

<p>Co-occuring condition. (A)</p> Signup and view all the answers

A patient is brought to the emergency department with acute onset of confusion, disorientation, and fluctuating levels of consciousness. The family reports that the patient has a history of well-controlled type 2 diabetes and has recently started taking a new medication for insomnia. Physical examination reveals mild tremor and tachycardia, but no focal neurological deficits. What is the MOST appropriate initial step in managing this patient?

<p>Conducting a thorough medication reconciliation and checking blood glucose levels. (A)</p> Signup and view all the answers

Which of the following is MOST suggestive of delirium rather than dementia?

<p>Acute disturbance in attention and awareness with fluctuating symptoms. (D)</p> Signup and view all the answers

A 55-year-old patient with a history of hypertension and hyperlipidemia presents with new-onset depressive symptoms, including anhedonia, fatigue, and difficulty concentrating. The patient reports no prior history of mental illness and denies any recent psychosocial stressors. Medical workup reveals evidence of previously undiagnosed subclinical hypothyroidism. Which of the following is the MOST appropriate initial treatment approach?

<p>Prescribing thyroid hormone replacement therapy and monitoring for improvement in depressive symptoms. (C)</p> Signup and view all the answers

A patient with metastatic breast cancer undergoing chemotherapy develops new-onset anxiety symptoms, including panic attacks and anticipatory anxiety. What is the most crucial step in differentiating anxiety disorder due to cancer treatment from a primary anxiety disorder?

<p>Looking for direct symptoms. (B)</p> Signup and view all the answers

A 40-year-old patient with no prior psychiatric history presents with acute onset of paranoia, disorganized thinking, and auditory hallucinations. Medical workup reveals that the patient has recently been diagnosed with systemic lupus erythematosus (SLE) and started on high-dose corticosteroids. Which of the following is the MOST likely cause of the patient's psychotic symptoms?

<p>Psychotic disorder due to systemic lupus erythematosus or corticosteroid use. (C)</p> Signup and view all the answers

Which of the following medical conditions is MOST closely associated with symptoms of anxiety?

<p>Hyperthyroidism. (A)</p> Signup and view all the answers

During an evaluation of a patient, the decision is made to recommend a neurology consult. What is the MAIN reason?

<p>To determine whether the symptoms could be caused by neurological causes. (C)</p> Signup and view all the answers

When approaching mental disorders, what needs to be determined before other things are considered?

<p>Whether symptoms are caused by a gernal medical condition. (B)</p> Signup and view all the answers

For patients with mental disorders caused by medical conditions, which patient population requires the greatest research?

<p>Patients with low socio-economic status. (B)</p> Signup and view all the answers

Which approach is most necessary towards improving patients with mental disorders caused by medical conditions?

<p>A multidisciplinary approach. (A)</p> Signup and view all the answers

When should patients be given emergent medications for conditions that are caused by other factors?

<p>If the patient continues to be highly symptomatic. (B)</p> Signup and view all the answers

Flashcards

What is psychiatry?

A medical discipline focused on the diagnosis, treatment, and prevention of mental, emotional, and behavioral disorders. Deals with and treats brain disorders.

What is the biopsychosocial model?

Biological, psychological, and social factors interplay. Used to explain human behavior and differentiate normal and abnormal patterns.

Psychosomatic medicine

A specific area of focus in medicine for more than 50 years. It refers to how the mind affects the body and how the body affects the mind.

Delirium

Disturbance of attention and awareness, accompanied by a change in baseline condition, reduced focus, and fluctuating symptoms, due to a direct physiological consequence of a medical condition.

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Dementia

Significant cognitive decline from a previous level of performance in one or more cognitive domains that include attention, executive function and social cognition.

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Secondary psychiatric symptoms

Psychiatric symptoms that are secondary to a medical condition or its treatments.

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Major Depressive Episode criteria

The episode is not attributable to psychological effects of a substance or to another medical condition.

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Depressive Disorder Due to Medical Condition

There is evidence from the history, physical examination, or laboratory findings that the disturbance is the direct pathophysiological consequence of another medical condition.

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Depression and Medical Condition

Begins, worsens, or improves in parallel with a medical condition, suggesting that the medical condition may be causative or contributory to depression.

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Sensory modality

Hallucinations can occur in any sensory modality visual, olfactory, gustatory, tactile, auditory.

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Anxiety Disorder

Panic attacks or anxiety is predominant in clinical picture.

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Mental Disorders Due to a General Medical Condition

Determine whether emergent symptomatic Rx needed.

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Psychiatric and medical disorders

Either predispose or worsen each other.

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Study Notes

  • Psychiatry is a medical discipline that deals with and treats brain disorders
  • Psyche means "soul" in Greek
  • Psychiatry uses a bio-psycho-social model, and tries to explain human behavior based on this
  • Psychiatry also tries to differentiate between normal and abnormal behavioral patterns in order to treat the person effectively

Psychosomatic Medicine

  • It focuses on how the mind affects the body and how the body affects the mind
  • Has been an area of focus for over 50 years

Bidirectional Relationship

  • There is a bidirectional relationship between the mind and the body

Psychiatric Symptoms Due to Medical Origin

  • These illnesses can come about gradually and be present after the age of 50

  • Features of a medical origin presents itself in:

    • Late onset of initial presentation
    • Known underlying medical condition
    • Atypical presentation of a specific psychiatric diagnosis
    • Absence of personal and family history of psychiatric illnesses
    • Illicit substance abuse
    • Medication use
    • Treatment resistance or unusual response to treatment
    • Sudden onset of symptoms
    • Abnormal vital signs
    • Waxing and waning mental status
  • Medical conditions that can cause psychiatric symptoms:

    • Absence of family history
    • Abnormal medical results
    • HIV treatments
    • Changes in mental status
    • Vital sign problems
    • Catatonia
    • Trouble with delirium
  • Dementia and delirium need an underlying medical cause

  • It's important to perform a medical evaluation so you can properly diagnose

Type of Clinical Problems in Psychosomatic Medicine

  • Psychiatric symptoms can be secondary to a medical condition
  • This includes delirium and dementia
  • The cognitive alteration can not be explained by a pre-existing neurocognitive disorder
  • These can be distinguished from a psychotic disorder due to a general medical condition in the presence of; confusion or significant intellectual deficits
  • Symptoms usually develop over a short period of time
  • Delirium has a disturbance of attention or awareness accompanied by a change in baseline condition
  • There is a reduced ability to direct, focus and shift attention
  • Symptoms tends to fluctuate
  • There is evidence from history, an examination, or lab findings that the disturbance is a direct physiological consequence of another medical condition

Causes of Delirium

  • This can be caused by: Infectious abscess, drug or alcohol Withdrawal, Acute metabolic disturbances, Trauma, CNS disease, Hypoxia, Deficiencies, Environmental factors, Acute vascular issues, Toxins, and Heavy metals (Use the I WATCH DEATH mnemonic)

Dementia

  • There is evidence of significant cognitive decline from a previous level of performance
  • Decline affects one or more cognitive domains like attention, executive function or social cognition
  • This includes Alzheimer’s disease, Frontotemporal lobar degeneration, Lewy body disease, and vascular disease

Medical Complications

  • Psychiatric symptoms can be secondary to medical treatments like anxiety related to chemotherapy or depression
  • Depression can also be related to obesity
  • Psychiatric issues can be complications from medical conditions and treatments like depression
  • Depression can be secondary to interferon treatment
  • Psychological factors can contribute to medical symptoms
  • A common example is Somatic symptom disorder

Other Medical Complications

  • Medical complications can be a result of psychiatric conditions or treatment
  • Lithium intoxication and Neuroleptic malignant syndrome, and acute withdrawal from alcohol
  • There can be co-occuring medical and psychiatric conditions such as End stage renal disease

Major Depressive Episode Criteria

  • Depressed mood
  • Loss of interest or pleasure
  • Significant weight loss or weight gain (5%)
  • Insomnia and/or hypersomnia
  • Psychomotor agitation or retardation
  • Fatigue, loss of energy
  • Feelings of worthlessness and/or excessive guilt
  • Diminished ability to think or concentrate
  • Recurring thoughts of death and/or suicidality
  • Must have 5 of 9 symptoms for 2 weeks
  • Symptoms must cause clinically significant distress or impairment in social area
  • The episode is not attributable to psychological effects of a substance or to another medical condition

Depressive Disorder

  • Depressed mood or markedly diminished interest or pleasure
  • The disorder cannot be explained by another mental disorder
  • Symptoms cause clinically significant distress or impairment in social or occupational areas
  • There is evidence from the history, physical examination, or lab findings that the disturbance is the direct pathophysiological consequence of another medical condition
  • The disturbance does not occur exclusively during the course of a delirium

Depression and General Medical Condition

  • Depression must begin, worsen, or improve in parallel with a medical condition
  • Depression should include Atypical symptoms
  • Practitioners best judgement is important for diagnosis
  • Neuroanatomical correlates of depression and MC
    • Stroke
    • Huntington's disease
    • Parkinson's disease
    • Traumatic brain injury
  • Neuroendocrine conditions
    • Cushing’s disease
    • Hypothyroidism

Medications that can induce depression:

  • Steroids
  • Alpha interferon

Psychotic Disorder Due to Another Medical Condition

  • Characterized by Prominent hallucinations or delusions

  • The disorder is not better explained by another mental disorder

  • There is evidence from history, physical examination, or laboratory findings that the disturbance is the direct pathophysiological consequence of another medical condition

  • There is not a disturbance occurring exclusively during the course of a delirium

  • In these cases Hallucinations can occur in any sensory modality

  • Temporal lobe epilepsy results in Olfactory hallucinations

  • Systemic lupus erythematosus
  • NMDA receptor autoimmune encephalitis
  • Temporal lobe epilepsy
  • Multiple sclerosis, Huntington's disease
  • Endocrine conditions (hyper/hypo thyroidism, hypo/hyperparathyroidism)
  • Metabolic conditions (hypoxia, hypercarbia etc.)

Anxiety Disorder Due to Another Medical Condition

  • The clinical picture includes Panic attacks or anxiety
  • There is evidence from the history, physical examination, or laboratory findings that the disturbance is the direct pathophysiological consequence of another medical condition
  • Anxiety is not better explained by another mental disorder
  • The disturbance does not occur exclusively during the course of a delirium
  • There is clinically significant distress or impairment in social or occupational areas
  • Endocrine disease (hyperthyroidism, pheochromocytoma, hypoglycemia, hyperadrenocortisolism)
  • Cardiovascular disease (congestive heart failure, pulmonary embolism, atrial fibrillation)
  • Metabolic disturbances (vit B 12 deficiency, porphyria)
  • Neurological illness (neoplasms, vestibular dysfunction, encephalitis, seizure disorders)

Approach for Mental Disorders

  • Mental disorders can result as a part of primary disorder or a medical condition

Approach for Mental Disorders Due to a General Medical Condition

  • Review the history and physical examination results
  • Review laboratory tests/imaging studies
  • Determine if mental symptoms are most likely a consequence of medical condition or better accounted for by a primary mental disorder
  • See if there is evidence for presence of a general medical condition that could plausibly cause the mental symptoms in question
  • If mental disorder is a result of medical condition, whether emergent symptomatic treatment is needed

Conclusion

  • Psychiatric and medical disorders either predispose or worsen each other
  • Drug-drug interaction and side-effect profile of medications has to be taken care of while prescribing in these illnesses
  • Close attention to the patient's symptomatology will help reduce their suffering
  • It is important for physicians and psychiatrists to have good understanding of both psychiatric and physical illness
  • The concomittant presence of both disorders leads to increased morbidity and mortality
  • Psychiatric disorders in medical illness pose a unique challenge considering their diagnosis and management

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