Introduction to Pharmacology and Drugs
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Questions and Answers

What defines a drug according to the provided content?

  • Any substance that can be obtained over-the-counter.
  • A substance that is only prescribed by a doctor.
  • A chemical substance used for a specific purpose, whether it's treatment, cure, prevention, or diagnosis, in humans or animals. (correct)
  • A substance that only affects the body, not the mind.
  • Which of the following is NOT a characteristic of prescription drugs, according to the provided text?

  • They are classified in various schedules and drug acts.
  • They require a medical prescription.
  • They can be purchased over-the-counter without a prescription. (correct)
  • They are typically dispensed by a registered medical practitioner.
  • What is the chemical name for the drug commonly known as Aspirin?

  • Ibuprofen
  • Acetyl salicylic acid (correct)
  • Paracetamol
  • Acetaminophen
  • Which of the following terms refers to the name assigned to a drug by the manufacturer for advertising purposes?

    <p>Proprietary name (C)</p> Signup and view all the answers

    Which of the following is an example of a Non-prescription drug, also known as OTC?

    <p>Paracetamol (B)</p> Signup and view all the answers

    What does the term 'Pharmacology' mean?

    <p>The study of the effects of drugs on living systems. (C)</p> Signup and view all the answers

    Which of the following name types describes the chemical composition of a drug?

    <p>Chemical name (B)</p> Signup and view all the answers

    What does the abbreviation 'RMP' stand for in the context of this content?

    <p>Registered Medical Practitioner (C)</p> Signup and view all the answers

    What is the main difference between pharmacokinetics and pharmacodynamics?

    <p>Pharmacokinetics focuses on how drugs move through the body, while pharmacodynamics focuses on the drug's effects on the body. (C)</p> Signup and view all the answers

    Which of the following is NOT a source of drugs?

    <p>Weather (A)</p> Signup and view all the answers

    What is the main purpose of the Controlled Substances Act (CSA) in the United States?

    <p>To regulate the production and distribution of drugs based on their potential for abuse. (A)</p> Signup and view all the answers

    Which of the following statements accurately describes Schedule I drugs under the CSA?

    <p>They have no accepted medical use and a high potential for abuse. (D)</p> Signup and view all the answers

    Which of the following drug classifications relates to the study of how the genetic makeup of individuals influences their responses to drugs?

    <p>Pharmacogenetics (D)</p> Signup and view all the answers

    Which of the following is an example of a drug derived from a plant?

    <p>Atropine (D)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of a non-proprietary name (generic name) of a drug?

    <p>Protected by patent. (B)</p> Signup and view all the answers

    Which of the following is an example of a Schedule II drug under the Controlled Substances Act?

    <p>Morphine (C)</p> Signup and view all the answers

    What is the potential for abuse and addiction of Schedule IV drugs compared to Schedule III drugs?

    <p>Schedule IV drugs have a lower potential for abuse and addiction. (A)</p> Signup and view all the answers

    Which of the following statements is NOT true about Schedule V drugs?

    <p>Their potential for dependence is higher than Schedule IV drugs. (A)</p> Signup and view all the answers

    What does the controlled substance symbol "C IV" indicate?

    <p>The drug is a Schedule IV controlled substance. (A)</p> Signup and view all the answers

    What is the historical significance of the Ebers Papyrus?

    <p>It documents the use of moldy bread to treat abrasions, predating the discovery of penicillin. (A)</p> Signup and view all the answers

    What was a significant contribution of the Greeks and Romans to the understanding of drugs?

    <p>They advanced the understanding of human anatomy and physiology. (B)</p> Signup and view all the answers

    What is the source of the drug digoxin (Lanoxin) used to treat congestive heart failure?

    <p>A plant derivative (C)</p> Signup and view all the answers

    Which of the following is an example of a drug derived from an animal source?

    <p>Thyroid supplement (D)</p> Signup and view all the answers

    What is the primary focus of ancient Chinese healing practices, as mentioned in the text?

    <p>Utilizing herbs and minerals alongside acupuncture, massage, and exercise (D)</p> Signup and view all the answers

    Which of the following minerals is an example of a trace mineral?

    <p>Selenium (C)</p> Signup and view all the answers

    What was the primary reason for the legislation of the Federal Food, Drug, Cosmetic Act in 1938?

    <p>To ensure drug effectiveness by requiring animal testing and <code>FDA</code> approval. (B)</p> Signup and view all the answers

    Which of the following was NOT a key feature of the Durham-Humphrey amendments to the Food, Drug, Cosmetic Act?

    <p>Requirement for animal testing for drug effectiveness. (B)</p> Signup and view all the answers

    What was the primary concern surrounding the use of cocaine in the 1885 advertisement for Cocaine Toothache Drops?

    <p>The ease of addiction to cocaine and its potential to become a public health crisis. (D)</p> Signup and view all the answers

    What is the primary role of the Federal government in drug legislation and regulation?

    <p>Enacting laws to ensure safety and effectiveness of drugs. (C)</p> Signup and view all the answers

    Flashcards

    Pharmacology

    The science of drugs and their effects on living systems.

    Drug

    A nonfood chemical substance affecting the mind or body, used for treatment or diagnosis.

    Non-prescription drugs

    Safe drugs sold over the counter without a prescription.

    Prescription drugs

    Drugs used under medical supervision, requiring a prescription from a registered practitioner.

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    Chemical name

    The name describing a drug's chemical constitution.

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    Proprietary name

    The brand name assigned to a drug by its manufacturer for marketing purposes.

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    Drug categories

    Classifications of drugs based on prescription requirements and safety.

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    Controlled substances

    Drugs regulated by laws due to their potential for abuse, classified into schedules.

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    Mineral-derived drugs

    Drugs that originate from minerals like calcium and iron used as supplements.

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    Cocaine Toothache Drops

    An 1885 product that contained cocaine, advertised for pain relief but addictive.

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    Federal Food and Drug Act

    A 1906 law that set standards for medication quality and labeling.

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    FDA Approval Process

    The requirement for pharmaceuticals to test drugs on animals before public release.

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    Durham-Humphrey Amendments

    1952 regulations requiring prescriptions for certain drugs and creating OTC categories.

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    Generic name

    Name assigned by a scientific body to a drug after its usefulness is established.

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    Pharmacokinetics

    Study of how a drug moves through the body during absorption, distribution, metabolism, and excretion.

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    Pharmacodynamics

    Study of what a drug does to the body and how it produces effects based on time and dosage.

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    Pharmacogenetics

    Study of how genetic makeup affects individual responses to drugs.

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    Sources of drugs

    Drugs can come from animals, plants, minerals, microbiological sources, or be synthetic.

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    Schedule drugs

    Controlled substances categorized by their potential for abuse as per the CSA.

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    Schedule I drugs

    Drugs with extremely high abuse potential, no accepted medical use, not available even with prescription.

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    Schedule II drugs

    Drugs with high abuse potential, accepted medical uses, require an official prescription.

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    Schedule IV

    Drugs with less potential for abuse than Schedule III, accepted medical uses, and limited dependence.

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    Schedule V

    Drugs with limited potential for abuse and currently accepted medical uses.

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    Controlled Substance Symbol

    A 'C' with a Roman numeral indicates the drug's control schedule, not its route of administration.

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    Ancient Egyptian Medicine

    Used various substances for treatment, including frogs' bile and moldy bread, which had therapeutic effects.

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    Ebers Papyrus

    An ancient Egyptian scroll containing 800 herbal formulations and prescriptions from 1500 B.C.

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    Drugs Derived from Plants

    Drugs like digoxin are made from plants, such as the foxglove, used to treat heart conditions.

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    Drugs Derived from Animals

    Drugs like thyroid supplements are made from desiccated animal tissues to treat hypothyroidism.

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    Contributions of Greeks and Romans

    Ancient cultures advanced medicine through an understanding of anatomy and physiology, influencing drug effects.

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    Study Notes

    Introduction to Pharmacology and History of Drugs

    • Pharmacology is the study of the effects of drugs on living systems
    • It studies drug mechanisms of action, therapeutic uses, adverse effects, and fate of drugs in humans or animals
    • A drug is a non-food chemical substance that affects the mind or body
    • Drugs are used to treat, cure, prevent, or diagnose diseases in humans and animals

    Learning Objectives

    • Define pharmacology and "drug"
    • List the major divisions of pharmacology
    • List different drug sources with examples
    • Define proprietary, non-proprietary, and chemical names of drugs
    • Define drug schedules and describe the five categories of controlled substances
    • Describe the various drug administration routes

    Drug Nomenclature

    • Drugs have 3 types of names: chemical name, proprietary name, and non-proprietary name
    • Chemical name: describes the chemical structure of a drug
    • Proprietary name: brand name assigned by the manufacturer (e.g., Aspirin: Disprin, Ecosprin; Paracetamol: Panadol, Crocin)
    • Non-proprietary name: generic name assigned by the scientific body (e.g., Aspirin and Paracetamol)

    Drug Categories

    • Non-prescription (OTC) drugs: safe and can be bought over-the-counter from chemists (e.g., vitamins, antacids, paracetamol).
    • Prescription drugs: require medical supervision (e.g., antibiotics, antihypertensives)

    Pharmacology Divisions

    • PharmacoKinetics: What the body does to the drug
      • Absorption, distribution, metabolism, and excretion
    • PharmacoDynamics: What the drug does to the body
      • Mechanism of action, desired and undesired effects, effects based on time and dosage

    Sources of Drugs

    • Animals (e.g., insulin, heparin, Vitamin B12)
    • Plants (e.g., morphine, digoxin, atropine, oils, gums, tannins)
    • Minerals (e.g., ferrous sulfate, sodium bicarbonate, magnesium sulfate)
    • Microbiological (e.g., penicillin from fungi)
    • Synthetic (e.g., analgesics, antimicrobials)
    • Genetic engineering (e.g., insulin)

    Schedule Drugs

    • Controlled substances under the Controlled Substances Act (CSA) with varying potential for abuse and addiction: divided into 5 schedules.

    • Schedule I: High potential for abuse and addiction, no currently accepted medical use, not available even with a prescription

    • Schedule II: High potential for abuse and addiction, currently accepted medical use, requires official prescription form; potential for severe physical and psychological dependence.

    • Schedule III: Less potential for abuse and addiction than Schedule II, currently accepted medical use, moderate physical and psychological dependence.

    • Schedule IV: Less potential for abuse and addiction than Schedule III, currently accepted medical use, limited-to-moderate physical or psychological dependence.

    • Schedule V: Limited potential for abuse, currently accepted medical use.

    Controlled Substance Symbol

    • The capital "C" indicates a controlled substance.
    • The number following the "C" (e.g., C-IV) represents the schedule number.

    History of Drugs

    • Ancient Egyptians (2000 B.C.) used various substances (e.g., frogs' bile, lizards' blood) for treating diseases.
    • Ancient Chinese used herbs and minerals with acupuncture.
    • Greeks and Romans studied anatomy and physiology.
    • 1600s: use of soap and mercury for various ailments.

    Modern Drugs Derived from Natural Sources

    • Plants (e.g., foxglove plant for digoxin, still used to treat heart failure)
    • Animals (e.g., thyroid supplements from animals for treating hypothyroidism)
    • Minerals (e.g., calcium, iron, copper, magnesium)

    Cocaine as a Common Drug

    • 1885 advertisement for Cocaine Toothache Drops.
    • Cocaine was not understood as highly addictive at this time.
    • Both children and adults became addicted.

    Drug Legislation and Agencies

    • Federal government: Protect consumers, regulate the industry, and enforce standards.
    • State government: Oversee practice and dispensing of drugs

    Federal and State Roles in Drug Regulation

    • Federal Food and Drug Act (1906): set quality standards for drugs; required proper labeling.
    • Federal Food, Drug, and Cosmetic Act (1938): further regulated drugs based on their effectiveness and required animal testing.
    • Durham-Humphrey amendments (1952): established prescription and non-prescription drug categories.

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    Description

    Explore the fundamentals of pharmacology, including drug mechanisms, classifications, and administration routes. This quiz will help you understand the history and definitions of drugs, their sources, and how they affect living systems. Gain knowledge about drug nomenclature and the categories of controlled substances.

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