Introduction to Pharmacognosy Quiz

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Questions and Answers

What is the primary focus of pharmacognosy?

  • Development of new pharmaceutical technologies
  • Study of synthetic drugs
  • Analysis of pharmaceutical marketing strategies
  • Study of drugs derived from natural sources (correct)

Which classification method arranges crude drugs by their Latin and English names?

  • Functional classification
  • Chemical classification
  • Taxonomical classification
  • Alphabetical classification (correct)

What is a major disadvantage of alphabetical classification in pharmacognosy?

  • It can lead to confusion over drug constituents.
  • It requires extensive background knowledge.
  • It is difficult to implement.
  • It does not reveal the source of the drug. (correct)

How is taxonomical classification characterized in pharmacognosy?

<p>According to phylogenetic similarities in plants (A)</p> Signup and view all the answers

Which of the following is NOT a merit of taxonomical classification?

<p>Offers insight into chemical constituents (C)</p> Signup and view all the answers

What does the term 'crude drug' refer to in pharmacognosy?

<p>Raw products from natural sources (D)</p> Signup and view all the answers

Which of the following is a merit of alphabetical classification?

<p>It allows easy addition of drug entries. (C)</p> Signup and view all the answers

Why is classification of crude drugs essential in pharmacognosy?

<p>For systematic and scientific study (A)</p> Signup and view all the answers

What percentage of organic matter characterizes poor soil?

<p>0.5% (C)</p> Signup and view all the answers

Which of the following plants grow better in alkaline soils?

<p>Rice (A)</p> Signup and view all the answers

What pH range is associated with maximum availability of plant nutrients?

<p>6.5 to 7.5 (D)</p> Signup and view all the answers

Which of the following is classified as a primary nutrient?

<p>Nitrogen (D)</p> Signup and view all the answers

What is an example of a synthetic auxin used in plant growth regulation?

<p>Indole butyric acid (IBA) (C)</p> Signup and view all the answers

Which of the following groups is categorized as organized drugs?

<p>Leaves and Flowers (C)</p> Signup and view all the answers

What is a major advantage of morphological classification?

<p>It helps in identifying and detecting adulteration. (B)</p> Signup and view all the answers

Which plant growth regulator stimulates stem growth through cell division and elongation?

<p>Gibberellins (A)</p> Signup and view all the answers

In pharmacological classification, which of the following drugs is grouped as a cardiotonic?

<p>Digitalis (A)</p> Signup and view all the answers

What effect do cytokinins have on leaf aging?

<p>Delay leaf aging (C)</p> Signup and view all the answers

What is a significant drawback of pharmacological classification?

<p>It includes multiple actions for single drugs leading to confusion. (A)</p> Signup and view all the answers

Which nutrient elements are necessary in very small quantities and are categorized as trace elements?

<p>Copper, manganese, and zinc (A)</p> Signup and view all the answers

Which of the following is considered an unorganized drug?

<p>Waxes (D)</p> Signup and view all the answers

What therapeutic action would vinca be classified under?

<p>Anticancer (A)</p> Signup and view all the answers

Which of the following represents an example where morphological classification may be more convenient?

<p>When adulteration is suspected. (B)</p> Signup and view all the answers

Which of the following is NOT a merit of pharmacological classification?

<p>It categorizes drugs based on their physical properties. (A)</p> Signup and view all the answers

What defines the chemical classification of drugs?

<p>The grouping of drugs based on their chemical constituents (D)</p> Signup and view all the answers

Which of the following is a correct example of a glycoside?

<p>Digitalis (C)</p> Signup and view all the answers

What is a significant characteristic of tannins?

<p>They are complex organic, non-nitrogenous compounds. (B)</p> Signup and view all the answers

Which of the following drugs contains both alkaloids and glycosides?

<p>Cinchona (D)</p> Signup and view all the answers

Which class of drugs is primarily derived from nitrogenous substances of plant origin?

<p>Alkaloids (B)</p> Signup and view all the answers

What is a drawback of chemical classification mentioned?

<p>It struggles with drugs containing multiple chemical types. (C)</p> Signup and view all the answers

Which of the following substances is a non-sugar derived from the hydrolysis of glycosides?

<p>Aglycone (B)</p> Signup and view all the answers

What does chemotaxonomical classification emphasize?

<p>The evolutionary relationships based on chemical constituents (B)</p> Signup and view all the answers

Which plant family is known to be rich in alkaloids?

<p>Apocynaceae (D)</p> Signup and view all the answers

What is one function of alkaloids in plants?

<p>To act as a protective mechanism against herbivores (A)</p> Signup and view all the answers

Which reagent produces a cream colored precipitate in the qualitative test for alkaloids?

<p>Mayer's reagent (B)</p> Signup and view all the answers

Which of the following is not a source of alkaloids in plants?

<p>Roots of Lily (D)</p> Signup and view all the answers

Which category of plants typically exhibits a higher concentration of alkaloids?

<p>Higher plants (A)</p> Signup and view all the answers

What is the ideal alcohol/water ratio for extracting compounds from barks, roots, woody parts, and seeds?

<p>7:3 or 8:2 (A)</p> Signup and view all the answers

Which of the following is NOT a method of extraction mentioned?

<p>Filtration (C)</p> Signup and view all the answers

What feature makes ethyl alcohol the solvent of choice for tinctures?

<p>All of the above. (D)</p> Signup and view all the answers

What is the main function of enzymes in cellular metabolism?

<p>To catalyze the digestion of nutrients. (D)</p> Signup and view all the answers

Which of the following is classified as a non-protoplasmic component?

<p>Alkaloids (C)</p> Signup and view all the answers

What is the primary reason for mixing ethanol with water during extraction processes?

<p>To induce swelling of plant particles. (A)</p> Signup and view all the answers

What characteristic of volatile oils differentiates them from other plant compounds?

<p>They are odorous and evaporate when exposed to air. (B)</p> Signup and view all the answers

Why are non-protoplasmic components considered useful for identification?

<p>They provide diagnostic value in identifying plant species. (D)</p> Signup and view all the answers

Flashcards

Pharmacognosy Definition

The study of drugs derived from natural sources, focusing on their physical, chemical, biochemical, and biological properties.

Crude Drug

A raw material from plants, animals, or minerals used in medicine.

Natural Drug Sources

Higher plants, microbes, animals, marine organisms, and minerals are common sources of medicines.

Alphabetical Classification

Organizing crude drugs by their Latin and English names in alphabetical order.

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Taxonomical Classification

Grouping crude drugs based on their plant's evolutionary relationships.

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Classification Purpose

Proper organization of crude drugs that is simple, easy to use, and minimizes confusion.

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Classification Merit (Alphabetical)

Easy to use, no repetition, and convenient for adding and locating drug entries.

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Classification Demerit (Alphabetical)

Does not show the source of the drug (plant, animal or mineral).

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Morphological Drug Classification

Grouping drugs based on their physical parts (e.g., leaves, roots) used as medicine.

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Organized Drugs

Crude drugs with recognizable cellular structures from plant parts like leaves, roots, etc.

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Unorganized Drugs

Crude drugs lacking visible cellular structures, like juices or resins.

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Pharmacological Drug Classification

Grouping drugs according to their effect on the body (e.g., anti-inflammatory, cardiotonic).

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Pharmacological Action

The specific effect a drug has on the body/patient (e.g., pain relief, blood pressure reduction).

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Cardiotonic Drug

Drugs that increase the force and efficiency of heart action.

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Drug Substitute

A similar drug used as a replacement for another drug if it's unavailable.

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Adulteration Detection

Identifying impurities or substitutions in a crude drug using morphology.

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Chemical Classification

Grouping crude drugs based on the chemical nature of their main constituent(s).

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Carbohydrates in Drugs

Polyhydroxy aldehydes or ketones with a carbon chain, like gums, mucilages, and starches.

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Glycosides

Compounds containing sugars (glycones) and non-sugar parts (aglycones), like anthraquinone glycosides and cardiac glycosides.

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Tannins

Complex organic molecules from polyhydroxy benzoic acids, found in many plants like catechu, galls, and myrobalan.

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Alkaloids

Nitrogenous substances of plant origin, like tropane, quinoline, and isoquinoline.

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Chemotaxonomical Classification

Classification based on the chemical similarities of related plants, considering the presence of specific constituents.

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Merit of Chemical Classification

Useful for phytochemical studies due to its focus on chemical composition.

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Demerit of Chemical Classification

Difficult to classify complex drugs with multiple chemical constituents, like Cinchona.

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Soil Richness

Soil containing more than 1.5% to 5% organic matter is considered rich. This high organic matter content promotes healthy plant growth due to increased nutrient availability and improved soil structure.

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Soil pH

The acidity or alkalinity of soil, measured on a scale of 0 to 14. Most plants thrive at a pH between 6.5 and 7.5, where nutrients are readily available.

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Alkaline Soil Plants

Plants like groundnut, sunflower seeds, cotton, and rice prefer alkaline soils, meaning soils with a pH above 7.

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Acidic Soil Plants

Plants such as tobacco, cinchona, tea, and potato thrive in acidic soils, meaning soils with a pH below 7.

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Plant Nutrients

Plants need 16 essential elements for growth and development. These elements are categorized into primary, secondary, and trace elements.

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Primary Nutrients

Nitrogen, phosphorus, and potassium are primary nutrients that plants need in large quantities for healthy growth.

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Plant Growth Regulators

Organic compounds that influence plant development and growth in small concentrations. They can be natural or synthetic.

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What are alkaloids?

Alkaloids are naturally occurring organic compounds that contain nitrogen and have a complex structure. They are found in plants, animals, and even some fungi.

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Where are alkaloids most commonly found?

Alkaloids are predominantly found in plants, particularly in higher plants. Of these, dicotyledonous plants (dicots) tend to have a higher concentration of alkaloids compared to monocots.

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Why do plants produce alkaloids?

Plants produce alkaloids to protect themselves from insects, herbivores, and other threats. Alkaloids are often bitter and toxic, deterring animals from eating them.

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What are some examples of alkaloids in plants?

Many plants contain alkaloids. For instance, Catharanthus plants have alkaloids in all their parts, while Cinchona plants have alkaloids in their bark.

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What are some diagnostic tests for alkaloids?

Specific reagents like Dragendorff's, Mayer's, Wagner's, and Hager's can be used to detect the presence of alkaloids in samples. These reagents cause the formation of precipitates with specific colors, indicating the presence of alkaloids.

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Tincture Solvent

The ideal solvent for a tincture should be highly selective for the target compound, unreactive with other components, affordable, safe for humans and the environment, and completely volatile.

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Ethanol's Role in Tinctures

Ethanol is the preferred solvent for tinctures due to its ability to extract a wide range of compounds from plants, including those soluble in both water and alcohol.

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Water's Role in Tinctures

Water is added to ethanol in tinctures to help swell plant particles, increase their porosity, and facilitate the extraction of substances from within the cells.

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Alcohol/Water Ratio in Tinctures

The optimal alcohol/water ratio for tinctures depends on the plant part being extracted. Roots, barks, and seeds typically use a higher alcohol concentration (7:3 or 8:2), while leaves and aerial parts often use a 1:1 ratio.

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Volatile Oils: Where They Live

Volatile oils, responsible for plant scents, are found in specialized plant parts like glandular hairs, parenchyma cells, oil tubes, and epidermal tissues.

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Cell Content: Protoplasts vs. Ergastic

Living protoplasts, such as the nucleus and cytoplasm, are not diagnostically useful for identifying plant material. Ergastic substances, like starch, crystals, and alkaloids, are non-living components and are more useful in identification.

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Maceration Extraction

This method involves soaking the plant material in a solvent for an extended period to extract the desired compounds.

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Percolation Extraction

Percolation uses a continuous flow of solvent through the plant material to extract the desired compounds efficiently.

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Study Notes

Introduction to Pharmacognosy

  • Pharmacognosy is the study of drugs derived from natural sources
  • It includes plants, animals, microorganisms, and minerals
  • It examines the physical, chemical, biochemical, and biological properties of naturally-originating drugs
  • The study also includes searching for novel drugs from natural sources
  • Synthetic drugs are excluded from the study
  • Pharmacognosy is related to botany, ethnobotany, marine biology, herbal medicine, chemistry (phytochemistry), pharmacology, and pharmaceutics

Crude Drugs

  • Crude drugs typically derive from plants, animals, or minerals in raw form
  • Important natural drug sources include higher plants, microbes, and marine organisms
  • Some useful products come from organic and inorganic minerals

Classification of Crude Drugs

  • A systematic classification is essential for detailed study
  • Simple and user-friendly methods are preferred for classification
  • Common approaches for crude drug classification include alphabetical, taxonomical, morphological, pharmacological, chemical, and chemotaxonomic classifications

Alphabetical Classification

  • Arranges drugs alphabetically based on Latin or English names (common names)
  • This method is used in many pharmacopoeias
  • Simple but lacks connection between the origin and properties of the drugs

Taxonomical Classification

  • A method of classification based on similarities in plant structure and family relationships
  • Arranges crude drugs based on the plant's taxonomic division, class, family, genus, and species
  • Helps to study the evolutionary development of drugs

Morphological Classification

  • Categorizes drugs according to the plant parts used, such as leaves, stems, roots, barks, flowers, fruits, and seeds
  • Subdivides crude drugs into organized and unorganized groups
  • Useful for identification and detection of adulteration

Pharmacological Classification

  • Classifies drugs based on their pharmacological action and therapeutic use
  • Groups drugs with similar actions
  • Useful for practical study and substitution of drugs when needed

Chemical Classification

  • Categorizes drugs based on the chemical nature of their major constituents
  • Helps in understanding the pharmacological activities and therapeutic applications of drugs
  • Valuable for suggesting substitutes for crude drugs

Chemotaxonomical Classification

  • Groups drugs based on the chemical similarity of a taxon
  • Explores the relationship between constituents and the evolution of plants
  • Based on chemical constituents that are characteristic of certain classes of plants

Cultivation, Collection, Drying, Storage, and Preparation of Crude Drugs

  • Cultivation offers advantages like uniform quality, improved collection, and control over soil quality
  • Factors influencing cultivation include altitude, temperature, soil quality, and rainfall
  • Proper drying methods help preserve and maintain the quality of the drug

Storage of Crude Drugs

  • Essential to store crude drugs in closed containers in dry conditions
  • Improper storage can lead to deterioration due to moisture, heat, air, light, fungi, bacteria, insects, and rodents

Pharmacognostic Evaluation of Medicinal Plants and Crude Drugs

  • Extraction prepares a solution or extracts of plants that contain all soluble constituents in the solvent
  • Tinctures are created by soaking crude drugs in alcohol
  • The solvent must be selective, cost-effective, harmless, and completely volatile
  • Many extraction techniques are available

Plant Growth Regulators

  • Organic compounds that affect the morphological structure or physiological processes in plants
  • Regulators are categorized into natural and synthetic classes
  • Functions include cell division, differentiation, root and shoot growth, and senescence (plant aging)

Plant Parts for Collection

  • The timing of collection is important for quality
  • Roots and rhizomes are usually collected in autumn
  • Barks are collected in the spring
  • Leaves are collected during the flowering stage
  • Flowers are usually collected after full development
  • Fruits and seeds are collected when ripe

Chemical Tests for Crude Drugs

  • Various tests are used to identify specific constituents present in crude drugs
  • These tests are valuable in determining the identity and quality of the crude drugs

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