Introduction to Medical Laboratory Sciences (MLS) for Year II Students
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Questions and Answers

What type of laboratories are adequate for working with microorganisms in risk group 1 and 2?

  • Maximum containment laboratories
  • Reference laboratories
  • Basic laboratories (correct)
  • Containment laboratories
  • Which of the following microorganisms belongs to risk group 2?

  • Staphylococci (correct)
  • Food spoilage bacteria
  • Marburg virus
  • M.tuberculosis
  • What type of laboratories are used for work with infectious organisms in risk group 3?

  • Reference laboratories
  • Maximum containment laboratories
  • Containment laboratories (correct)
  • Basic laboratories
  • What is a characteristic of a containment laboratory?

    <p>It is a separate room with controlled access</p> Signup and view all the answers

    What type of laboratories are intended for work with viruses in risk group 4?

    <p>Maximum containment laboratories</p> Signup and view all the answers

    What is a characteristic of a maximum containment laboratory?

    <p>It has strictly controlled access through decontaminant showers</p> Signup and view all the answers

    What type of laboratories perform routine diagnostic and follow-up lab tests?

    <p>Peripheral laboratories</p> Signup and view all the answers

    What type of laboratories may conduct additional tests than those provided in peripheral laboratories?

    <p>Intermediate-level laboratories</p> Signup and view all the answers

    What type of laboratories can serve as referral laboratories for some special tests?

    <p>Intermediate-level laboratories</p> Signup and view all the answers

    What type of laboratories carry out management and supervisory tasks under specific areas of jurisdiction?

    <p>Intermediate-level laboratories</p> Signup and view all the answers

    Match the following types of laboratories with their characteristics:

    <p>Basic laboratories = Adequate for work with microorganisms in risk group 1 and 2 Containment laboratories = Used for work with infectious organisms in risk group 3 Maximum containment laboratories = Intended for work with viruses in risk group 4 Peripheral laboratories = Performing routine diagnostic and follow-up lab tests</p> Signup and view all the answers

    Match the following laboratory types with their functions:

    <p>Peripheral laboratories = Performing routine diagnostic and follow-up lab tests Intermediate-level laboratories = Conducting additional tests and serving as referral laboratories Reference laboratories = Providing specialized testing and expertise Maximum containment laboratories = Handling viruses in risk group 4</p> Signup and view all the answers

    Match the following microorganisms with their risk groups:

    <p>Food spoilage bacteria = Risk group 1 Staphylococci = Risk group 2 M. tuberculosis = Risk group 3 Marburg virus = Risk group 4</p> Signup and view all the answers

    Match the following laboratory characteristics with their types:

    <p>Controlled access and microbiological safety cabinet = Containment laboratory Decontaminant showers and filtered air discharge = Maximum containment laboratory Separate room with restricted access = Containment laboratory Routine diagnostic and follow-up lab tests = Peripheral laboratory</p> Signup and view all the answers

    Match the following laboratory tasks with their levels:

    <p>Management and supervisory tasks = Intermediate-level laboratories Routine diagnostic and follow-up lab tests = Peripheral laboratories Specialized testing and expertise = Reference laboratories High-risk virus handling = Maximum containment laboratories</p> Signup and view all the answers

    Match the following laboratory features with their types:

    <p>Separate building with controlled access = Maximum containment laboratory Microbiological safety cabinet = Containment laboratory Ventilation system with filtered air discharge = Maximum containment laboratory Referral services for special tests = Intermediate-level laboratories</p> Signup and view all the answers

    Match the following microorganisms with their laboratory handling:

    <p>Yeasts = Basic laboratory Streptococci = Basic laboratory HIV = Containment laboratory SARS virus = Maximum containment laboratory</p> Signup and view all the answers

    Match the following laboratory types with their testing capabilities:

    <p>Peripheral laboratories = Routine diagnostic and follow-up lab tests Intermediate-level laboratories = Additional tests beyond peripheral labs Reference laboratories = Specialized testing and expertise Maximum containment laboratories = High-risk virus handling</p> Signup and view all the answers

    Match the following laboratory tests with their respective medical conditions:

    <p>Hemoglobin = Anemia Glucose = Diabetes Mellitus Urinalysis = Kidney Function Immunohematology = Blood Transfusion</p> Signup and view all the answers

    Match the following laboratory departments with their respective areas of focus:

    <p>Hematology = Blood Constituents Clinical Chemistry = Biochemicals in Body Fluids Microbiology = Microorganisms Immunology/Serology = Antigen-Antibody Concept</p> Signup and view all the answers

    Match the following laboratory tests with their respective areas of application:

    <p>Parasitology = Parasites Mycology = Fungi Virology = Viral Diseases Bacteriology = Bacteria</p> Signup and view all the answers

    Match the following laboratory tests with their respective biological molecules:

    <p>Molecular Biology = DNA and RNA Immunohematology = Proteins and Enzymes Clinical Chemistry = Nucleic Acids Hematology = Proteins</p> Signup and view all the answers

    Match the following laboratory departments with their respective areas of focus:

    <p>Cytology = Cellular Analysis Histopathology = Tissue Analysis Parasitology = Parasites Urinalysis = Urine Analysis</p> Signup and view all the answers

    Match the following laboratory types with their respective risk levels:

    <p>Basic Laboratories = Low Risk Containment Laboratories = Moderate Risk Maximum Containment Laboratories = High Risk Public Health Laboratories = Community Risk</p> Signup and view all the answers

    Match the following laboratory tests with their respective areas of application:

    <p>Immunohematology = Blood Transfusion Microbiology = Infectious Diseases Molecular Biology = Genetic Analysis Clinical Chemistry = Metabolic Disorders</p> Signup and view all the answers

    Match the following laboratory professionals with their respective areas of expertise:

    <p>Clinical Chemist = Biochemical Analysis Microbiologist = Microorganism Identification Hematologist = Blood Disorder Diagnosis Immunologist = Antibody Response Analysis</p> Signup and view all the answers

    Match the following laboratory tests with their purposes:

    <p>Lipid profile = Disease diagnosis Acid fast staining = Screening Prostate specific antigen = Monitoring Blood film = Diagnosis</p> Signup and view all the answers

    Match the following entities with their roles in the history of medical laboratory in Ethiopia:

    <p>Italians = Established Ministro Dela Sanita British = Established Imperial Medical Research Institute French team = Established Institute Pasteur d' Ethiopie Ethiopian professionals = Established Ethiopian Public Health Institute</p> Signup and view all the answers

    Match the following limitations of physical examination with their reasons:

    <p>Many S/S may not be specific for any particular disease = Missed diagnosis Some diseases may be asymptomatic = Poor disease outcome Patients often forget symptoms = Subjective symptoms Symptoms are subjective and hence may be psychological = Unreliable diagnosis</p> Signup and view all the answers

    Match the following types of laboratory tests with their purposes:

    <p>Screening = Detection of disease at early stage Diagnosis = Confirmation of clinical diagnosis Monitoring = Follow-up of treatment response Treatment = Administration of medication</p> Signup and view all the answers

    Match the following milestones with their years in the history of medical laboratory:

    <p>Formal training of laboratory professionals started = 1954 Well-organized MLS program developed = 1950s and 1960s Medical laboratory service began in Lambie Hospital = Early 20th century Ethiopian Public Health Institute established = Late 20th century</p> Signup and view all the answers

    Match the following laboratory tests with their applications:

    <p>Lipid profile = Cardiovascular disease risk Acid fast staining = Tuberculosis diagnosis Prostate specific antigen = Prostate cancer screening Blood film = Malaria diagnosis</p> Signup and view all the answers

    Match the following laboratory professionals with their roles:

    <p>MLS professionals = Conducting laboratory tests Medical researchers = Developing new diagnostic techniques Laboratory technicians = Assisting in laboratory tests Public health officials = Overseeing laboratory operations</p> Signup and view all the answers

    Match the following laboratory testing methods with their benefits:

    <p>Laboratory testing = Aid to medical diagnosis Screening tests = Early detection of diseases Diagnostic tests = Confirmation of clinical diagnosis Monitoring tests = Follow-up of treatment response</p> Signup and view all the answers

    Study Notes

    Basics to Medical Laboratory Sciences

    Definition of Laboratory and Medical Laboratory

    • A laboratory is a room, building, or institution equipped for testing, experimentation, or scientific research.
    • A medical laboratory is a health facility where tests are done on body fluids to acquire information about a patient's health for diagnosis, treatment, and prevention of disease or medical research.

    History of Medical Laboratory Science

    • The beginning of medical laboratory science is not well known, but urine examination dates back to ancient Egypt around 400 BC.
    • The first organized clinical laboratory was opened at Johns Hopkins Hospital in the USA in 1896.
    • Laboratory work was initially performed by physicians, but as diagnostic tests grew, they relied on laboratory assistants.
    • The creation of diversified training programs for laboratory professionals began during World War I, and a well-organized MLS program developed in the 1950s and 1960s.

    History of Medical Laboratory in Ethiopia

    • Medical laboratory service began in Lambie Hospital, which was renamed 'Ministro Dela Sanita' by Italians, then 'Imperial Medical Research Institute' by the British, and finally 'Institute Pasteur d' Ethiopie' by the French.
    • Ethiopian professionals took over the responsibility, and the Ethiopian Public Health Institute (EPHI) was established.
    • Formal training of laboratory professionals started in 1954.

    Importance of Laboratory Testing

    • Laboratory tests are necessary for aiding medical diagnosis, as physical examination alone can lead to misdiagnosis and poor disease outcome.
    • Laboratory tests are used for screening, diagnosis, and monitoring diseases.
    • Examples of laboratory tests include lipid profile for cardiovascular disease, prostate-specific antigen for prostate cancer, acid-fast staining for tuberculosis, and blood film for malaria.

    Medical Laboratory Department/Units

    • The organization of a clinical laboratory depends on its size, number of tests, and available facilities.
    • Departments/units include urinalysis, hematology, parasitology, clinical chemistry, immunology/serology, microbiology, molecular biology, cytology, and immunohematology.
    • Each department/unit has a specific function, such as examination of blood constituents, measurement of biochemicals, and detection of microorganisms.

    Classification of Laboratories

    • The World Health Organization (WHO) classifies laboratories based on risk levels as basic, containment, and maximum containment laboratories.
    • Basic laboratories deal with microorganisms in risk groups 1 and 2, while containment laboratories are used for work with infectious organisms in risk group 3.
    • Maximum containment laboratories are used for work with viruses in risk group 4, requiring the strictest safety precautions.

    Structure of Laboratory Services

    • The structure of laboratory services consists of peripheral, intermediate-level, and reference laboratories.
    • Peripheral laboratories perform routine diagnostic and follow-up tests.
    • Intermediate-level laboratories conduct additional tests and serve as referral laboratories for special tests, carrying out management and supervisory tasks.

    Laboratory Classification

    • Primary health care and hospital diagnostic labs are adequate for working with microorganisms in risk groups 1 and 2.
    • Risk group 1 includes food spoilage bacteria and yeasts.
    • Risk group 2 includes Staphylococci and Streptococci.
    • Containment laboratories are more advanced and used for work with infectious organisms in risk group 3, such as M. tuberculosis and HIV.
    • Maximum containment laboratories are intended for work with viruses in risk group 4, such as Marburg virus, Ebola virus, and SARS virus, and require strict safety precautions.

    Laboratory Structure and Services

    • The structure of laboratory services includes reference laboratories, intermediate-level laboratories, and peripheral laboratories.
    • Peripheral laboratories perform routine diagnostic and follow-up lab tests.
    • Intermediate-level laboratories conduct additional tests and serve as referral laboratories for special tests, while carrying out management and supervisory tasks.

    History of Medical Laboratory

    • Medical laboratory service began in Lambie Hospital, which was later renamed and reorganized by Italians, British, and French teams.
    • Ethiopian professionals eventually took over and established the Ethiopian Public Health Institute (EPHI).
    • Formal training of laboratory professionals started in 1954.

    Importance of Laboratory Testing

    • Laboratory tests are necessary as an aid to medical diagnosis, as physical examination alone can lead to missed diagnoses and poor disease outcomes.
    • Laboratory testing is used for screening, diagnosis, and monitoring.
    • Examples of screening include lipid profiles for cardiovascular disease and prostate-specific antigen for prostate cancer.
    • Examples of diagnosis include acid-fast staining for tuberculosis and blood films for malaria.
    • Examples of monitoring include hemoglobin to check anemia treatment and glucose for diabetes.

    Medical Laboratory Departments

    • Medical laboratory departments/units include urinalysis, hematology, parasitology, clinical chemistry, immunology/serology, immunohematology, microbiology, molecular biology, cytology, bacteriology, virology, mycology, histopathology, and public health.
    • Hematology involves the examination of blood constituents.
    • Clinical chemistry measures biochemicals in body fluids.
    • Medical microbiology deals with medically important microorganisms, including bacteria, viruses, and fungi.
    • Parasitology deals with parasites.

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    An overview of medical laboratory sciences, covering its definition, history, and other essential concepts for second-year students. This quiz is designed to test your understanding of the basics of MLS.

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