18 Questions
What is the primary function of hemoglobin in red blood cells?
To transport oxygen from the lungs to the tissues
What is the advantage of hemoglobin's tetrameric structure over myoglobin?
It allows for the transport of H+ and CO2
What is the structural difference between hemoglobin and myoglobin?
Myoglobin has a single polypeptide chain, while hemoglobin has four
What is the role of hemoglobin in the transport of oxygen and carbon dioxide?
It transports oxygen from the lungs to the tissues and carbon dioxide from the tissues to the lungs
What is the similarity between hemoglobin and myoglobin?
They both have a structurally similar polypeptide chain
What is the function of myoglobin in muscle cells?
To store oxygen in the muscles
What is the main function of hemoglobin in red blood cells?
To transport oxygen from the lungs to the tissues
What is the role of the heme group in hemoglobin?
To reversibly bind oxygen
What is the state of iron in the heme group of hemoglobin?
Ferrous (Fe2+)
What is the function of myoglobin in heart and skeletal muscle?
To serve as a reservoir for oxygen and increase oxygen transport within the muscle cell
What is the composition of normal hemoglobin?
Four globin chains and four heme groups
What is the additional molecule found in hemoglobin, besides globin and heme groups?
2,3-Diphosphoglycerate (2,3-DPG)
What is the composition of normal hemoglobin?
A tetramer of two unlike globin polypeptide chains and four heme groups
What is the effect of oxidation of the heme component of hemoglobin to the ferric state?
Decreased oxygen binding capacity
What is the role of 2,3-diphosphoglycerate (2,3DPG) in hemoglobin?
To decrease oxygen binding capacity
What is the effect of carbon monoxide on hemoglobin?
It replaces oxygen bound to hemoglobin
What is the result of sulfur buildup in the blood?
Formation of sulfhemoglobin
What is the consequence of methemoglobin formation?
Decreased oxygen binding capacity
Learn about the structure and function of hemoglobin, a tetrameric protein composed of four polypeptide chains, and its role in transporting oxygen and carbon dioxide in the body. Compare and contrast hemoglobin with myoglobin, another hemeprotein. Understand the synthesis of hemoglobin and its importance in the human body.
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