Hemoglobin Synthesis and Functions Quiz
8 Questions
4 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the main function of red cells?

  • To carry waste products away from the tissues
  • To return carbon dioxide from the tissues to the lungs (correct)
  • To produce haemoglobin
  • To carry nutrients to the tissues

Which molecule is the dominant haemoglobin in blood after the age of 3–6 months?

  • Hb A (correct)
  • Hb A2
  • Hb S
  • Hb F

How many polypeptide chains are there in a molecule of normal adult haemoglobin A (Hb A)?

  • Two
  • Four (correct)
  • One
  • Three

Which enzyme is the key rate‐limiting enzyme for haem synthesis?

<p>$ ext{δ‐aminolaevulinic acid}$ (ALA) synthase (A)</p> Signup and view all the answers

Which coenzyme is required for the synthesis of haem?

<p>$ ext{Pyridoxal phosphate}$ (vitamin B6) (B)</p> Signup and view all the answers

What combines with iron to form haem?

<p>$ ext{Protoporphyrin}$ (D)</p> Signup and view all the answers

Which variant form of normal hemoglobin contains sulfur?

<p>$ ext{Sulfhemoglobin}$ (B)</p> Signup and view all the answers

What is the main function of variant forms of normal hemoglobin?

<p>$ ext{To cause tissue damage}$ (A)</p> Signup and view all the answers

Study Notes

Red Blood Cell Function

  • The primary function of red blood cells is to transport oxygen from the lungs to body tissues and return carbon dioxide from tissues back to the lungs.

Dominant Hemoglobin Type

  • After 3–6 months of age, the dominant hemoglobin in blood is hemoglobin A (Hb A), which is crucial for efficient oxygen transport.

Composition of Adult Hemoglobin

  • Normal adult hemoglobin A (Hb A) is composed of four polypeptide chains, specifically two alpha chains and two beta chains.

Key Enzyme for Hemoglobin Synthesis

  • The key rate-limiting enzyme for hem synthesis is porphobilinogen deaminase, essential for the production of heme groups.

Coenzyme for Hem Synthesis

  • The synthesis of heme requires the coenzyme pyridoxal phosphate, which is derived from vitamin B6.

Iron in Heme Formation

  • Iron combines with protoporphyrin IX to form heme, which is vital for the function of hemoglobin in oxygen transport.

Variant Hemoglobin with Sulfur

  • Hemoglobin S (Hb S) is a variant form of normal hemoglobin that contains sulfur and is primarily associated with sickle cell disease.

Function of Variant Hemoglobins

  • The main function of variant forms of normal hemoglobin, such as Hb S, is to supply oxygen, although they may lead to structural changes that can impair red blood cell function and oxygen delivery.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Description

Test your knowledge on hemoglobin synthesis and its main function in red blood cells. Understand the structure of normal adult hemoglobin A and its role in gaseous exchange within the body.

More Like This

Introduction to Hemoglobin Synthesis
18 questions
Decreased RBC Production Quiz
38 questions

Decreased RBC Production Quiz

InvaluableStatistics3928 avatar
InvaluableStatistics3928
Microcytic Anemia Overview
30 questions

Microcytic Anemia Overview

ResilientSwaneeWhistle1200 avatar
ResilientSwaneeWhistle1200
Use Quizgecko on...
Browser
Browser