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Questions and Answers

What is the term for a hormone that diffuses locally to act on a different cell type?

  • Exocrine
  • Autocrine
  • Paracrine (correct)
  • Endocrine

Which type of hormone signaling involves the release of neurotransmitters at synaptic junctions?

  • Endocrine
  • Synaptic (correct)
  • Paracrine
  • Exocrine

In which type of hormone transmission is the bloodstream the main mode of transportation?

  • Synaptic
  • Paracrine
  • Autocrine
  • Endocrine (correct)

Which type of hormone communication involves the release of hormones into the bloodstream to act on distant target cells?

<p>Endocrine transmission (A)</p> Signup and view all the answers

What is the primary focus of the Introduction to Endocrinology lecture?

<p>The coordination of body functions via chemical messengers (B)</p> Signup and view all the answers

In endocrinology, what is the significance of identifying major endocrine glands and their hormones?

<p>Recognizing the glands responsible for hormone production and their associated hormones (C)</p> Signup and view all the answers

What is one of the objectives when comparing down-regulation and up-regulation of hormone receptors?

<p>Exploring how cells regulate their responsiveness to hormones (C)</p> Signup and view all the answers

Why is it important to compare the chemical structures and implications of the three main classes of hormones in endocrinology?

<p>To understand the variety and functions of different hormone types in the body (D)</p> Signup and view all the answers

Which type of hormone secretion is characterized by simple negative feedback?

<p>Hormone secretion from a primary target gland (A)</p> Signup and view all the answers

What controls hormone secretion from the anterior pituitary according to negative feedback mechanisms?

<p>Hormones controlled by hypothalamic factors (C)</p> Signup and view all the answers

Which hormones are typically controlled by hypothalamic factors?

<p>Anterior pituitary hormones (C)</p> Signup and view all the answers

Why is a single blood sample considered less useful than stimulation tests for hormone secretion?

<p>To measure rhythmic patterns of secretion (B)</p> Signup and view all the answers

What is a role of Active COX-1 in the body?

<p>Maintaining gastrointestinal epithelium integrity (A)</p> Signup and view all the answers

What is the function of Leukotrienes in allergic responses and inflammation?

<p>Attracting neutrophils and eosinophils to inflammatory sites (A)</p> Signup and view all the answers

Which condition is associated with PGD2 and PGF2α causing bronchoconstriction?

<p>Asthma (D)</p> Signup and view all the answers

How do glucocorticoids impact leukotrienes production?

<p>Inhibit their production (C)</p> Signup and view all the answers

Which type of hormone receptors are lipid-soluble and interact with receptors in the cytoplasm or nucleus?

<p>Intracellular hormone receptors (C)</p> Signup and view all the answers

What effect does down-regulation of hormone receptors have on a target tissue's responsiveness to the hormone?

<p>Decreases responsiveness (D)</p> Signup and view all the answers

Which enzyme is commonly used by second messengers to change cellular activity by phosphorylating target proteins?

<p>Kinase (D)</p> Signup and view all the answers

Which second messenger is produced by membrane-bound enzyme phospholipase C and causes Ca++ release from ER stores?

<p>IP3 (B)</p> Signup and view all the answers

How do G protein-linked hormone receptors alter cellular activity?

<p>Open or close ion channels (C)</p> Signup and view all the answers

Which receptor type acts as or with enzymes when activated and directly initiates cascades of phosphorylation reactions within the cell?

<p>Enzyme-linked hormone receptor (A)</p> Signup and view all the answers

What is the primary function of Diacylglycerol (DAG) in cellular responses?

<p>Activates protein kinase C (B)</p> Signup and view all the answers

How does up-regulation of hormone receptors affect the target tissue's sensitivity?

<p>Increases sensitivity (C)</p> Signup and view all the answers

What is the main effect of activating gene transcription through receptor tyrosine kinases?

<p>Increased protein synthesis (B)</p> Signup and view all the answers

Leukotrienes are involved in allergic responses, but not in inflammation.

<p>False (B)</p> Signup and view all the answers

Cytokines produced by immune system cells never cross the blood-brain barrier.

<p>False (B)</p> Signup and view all the answers

Glucocorticoids increase the activity of phospholipase A2, leading to increased leukotriene production.

<p>False (B)</p> Signup and view all the answers

Prostaglandins released from damaged tissues directly inhibit the activation of nociceptors.

<p>False (B)</p> Signup and view all the answers

Cytokines produced by immune system cells play a role in resetting the body's temperature control center.

<p>True (A)</p> Signup and view all the answers

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