Introduction to Cardiovascular Physiology
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Questions and Answers

What is the average heart rate in adults?

  • 80 beats/min
  • 90 beats/min
  • 72 beats/min (correct)
  • 60 beats/min

Which factor is known to decrease heart rate?

  • Stress
  • High body temperature
  • Exercise
  • Parasympathetic stimulation (correct)

What is the stroke volume in adults?

  • 90 ml/beat
  • 70 ml/beat
  • 80 ml/beat (correct)
  • 60 ml/beat

How does sympathetic stimulation affect cardiac output?

<p>It increases cardiac output. (A)</p> Signup and view all the answers

During which phase of the cardiac cycle does blood pass from the atria to the ventricles?

<p>Atrial systole (A)</p> Signup and view all the answers

What separates the right atrium from the right ventricle?

<p>Tricuspid valve (C)</p> Signup and view all the answers

Which vessels carry oxygenated blood away from the heart?

<p>Aorta (A)</p> Signup and view all the answers

What is the function of the heart valves?

<p>Allow blood flow in one direction only (C)</p> Signup and view all the answers

What structures prevent the eversion of the A-V valves during ventricular contraction?

<p>Chordae tendineae (A), Papillary muscle (D)</p> Signup and view all the answers

Which part of the heart starts the systemic circulation?

<p>Left ventricle (A)</p> Signup and view all the answers

Which type of circulation is responsible for sending deoxygenated blood to the lungs?

<p>Pulmonary circulation (C)</p> Signup and view all the answers

What is the role of the atria in the heart?

<p>Receiving blood from the body and lungs (C)</p> Signup and view all the answers

What connects the papillary muscles to the atrioventricular valves?

<p>Chordae tendineae (D)</p> Signup and view all the answers

What role does the sino-atrial node play in the heart's function?

<p>It initiates the electrical impulse that triggers heartbeats. (C)</p> Signup and view all the answers

What is cardiac output a product of?

<p>Heart rate and stroke volume. (D)</p> Signup and view all the answers

During which stage of the cardiac cycle does blood return to the atria from the body?

<p>Atrial diastole. (C)</p> Signup and view all the answers

How does thyroxin influence cardiac output?

<p>It increases cardiac output. (D)</p> Signup and view all the answers

What is the primary role of the ventricles in the heart?

<p>Pumping blood to the whole body (A)</p> Signup and view all the answers

What type of blood is delivered by the aorta?

<p>Oxygenated blood (C)</p> Signup and view all the answers

What separates the left atrium from the left ventricle?

<p>Bicuspid (mitral) valve (C)</p> Signup and view all the answers

What is the function of the pericardium?

<p>To protect the heart and reduce friction (D)</p> Signup and view all the answers

Which structure collects deoxygenated blood returning from the body?

<p>Right atrium (C)</p> Signup and view all the answers

Which component prevents the backflow of blood into the ventricles during contraction?

<p>A-V valves (C)</p> Signup and view all the answers

Which valve allows blood to exit the left ventricle into the aorta?

<p>Aortic valve (D)</p> Signup and view all the answers

What are the two primary divisions of the circulatory system?

<p>Systemic and pulmonary (B)</p> Signup and view all the answers

Flashcards

Heart Rate

The number of heartbeats per minute. A normal range for adults is 60-90 bpm.

Sino-atrial (SA) Node

The pacemaker of the heart, located in the right atrium. It initiates the electrical impulse that starts each heartbeat.

Cardiac Output

The amount of blood pumped by each ventricle per minute. Measured in liters per minute.

Stroke Volume

The amount of blood pumped by each ventricle with each beat. Measured in milliliters per beat.

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Cardiac Cycle

One complete sequence of contraction (systole) and relaxation (diastole) of the heart.

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Pericardium

A connective tissue sac surrounding the heart, protecting it and minimizing friction during contraction.

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Atrioventricular (A-V) valves

Valves located between the atria and ventricles of the heart, preventing backflow of blood during contraction.

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Chordae Tendineae

Tendons connecting papillary muscles to atrioventricular valves, preventing their inversion during ventricular contraction.

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Systemic Circulation

The part of blood circulation that carries oxygenated blood from the heart to the body and returns deoxygenated blood to the heart.

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Pulmonary Circulation

The part of blood circulation that carries deoxygenated blood from the heart to the lungs, and returns oxygenated blood to the heart.

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Right Ventricle

Pumps deoxygenated blood to the lungs.

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Left Ventricle

Pumps oxygenated blood to the body.

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Heart Valves Function

Allow blood flow in one direction only to ensure efficient circulation.

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What is pericardium?

A connective tissue sac that encloses the heart, protecting it and minimizing friction during contractions.

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What are the divisions of the heart?

The heart is divided into a right and left half, each consisting of an atrium and a ventricle.

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Tricuspid valve

The valve separating the right atrium from the right ventricle, preventing backflow of blood.

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Bicuspid/Mitral valve

The valve separating the left atrium from the left ventricle, preventing backflow of blood.

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Papillary muscle

Muscle located within the ventricles, connected to the A-V valves by chordae tendineae.

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What is the function of the aorta?

The aorta carries oxygenated blood from the left ventricle to the whole body.

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Pulmonary artery

The artery carrying deoxygenated blood from the right ventricle to the lungs.

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What initiates the heartbeat?

The sino-atrial (SA) node, located in the right atrium, generates an electrical impulse that triggers the heart's contraction.

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How does the impulse travel?

The electrical impulse from the SA node spreads through the atria, causing them to contract. It then reaches the atrioventricular (AV) node, which delays the signal before sending it to the ventricles via the His-Purkinje system.

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What influences heart rate?

Both the sympathetic and parasympathetic nervous systems influence heart rate. Sympathetic stimulation (fight or flight) increases heart rate, while parasympathetic stimulation (rest and digest) decreases it.

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What is a cardiac cycle?

One complete sequence of heart contraction (systole) followed by relaxation (diastole). It includes atrial and ventricular phases.

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Study Notes

Introduction to Cardiovascular Physiology

  • Presented by Dr. Sherif Diaaeldin, Assistant Professor of Physiology at Ain Shams University.

Functional Anatomy of the Heart

  • The heart is a hollow muscular organ enclosed by the pericardium, a connective tissue sac.
  • The pericardium protects the heart, reducing friction during contractions.
  • The heart wall is composed of cardiac muscle.
  • The heart is divided into right and left halves, each with one atrium and one ventricle.

Heart Valves

  • The right atrium is separated from the right ventricle by the tricuspid valve.
  • The left atrium is separated from the left ventricle by the bicuspid (mitral) valve.
  • Both valves are called atrioventricular (A-V) valves.
  • Within the ventricles are papillary muscles, with chordae tendineae attached. This prevents the valves from inverting during ventricular contraction.

Divisions of the Circulation

  • Systemic circulation: Begins in the left ventricle, then flows through the aorta, arteries, arterioles, capillaries, venules, and veins, returning to the superior and inferior venae cavae, and into the right atrium.
  • Pulmonary circulation: Begins in the right ventricle, then flows through the pulmonary artery, pulmonary capillaries, pulmonary veins, and into the left atrium.

Functions of the Atria and Ventricles

  • Atria are entryways to the ventricles.
  • Ventricles pump blood throughout the body (right to lungs, left to body). 
  • Oxygenated blood leaves the heart via the aorta.
  • Deoxygenated blood enters the heart via the vena cavae and exits via the pulmonary artery to the lungs.
  • Pulmonary veins carry oxygenated blood back to the heart. 

Mechanism of Heart Beating

  • Heart rate averages 72 beats per minute in adults.
  • The sinoatrial (SA) node, located in the right atrium, initiates the heartbeat.
  • The impulse from the SA node spreads through the atria causing them to contract.
  • The impulse reaches the atrioventricular (AV) node, then travels through the Bundle of His and Purkinje fibers to the ventricles, causing ventricular contraction.

Factors Affecting Heart Rate

  • Increased heart rate: Sympathetic stimulation, exercise, increased body temperature (every degree Celsius increases the heart rate by 10 beats per minute), fever, hormones (thyroxin and adrenalin).
  • Decreased heart rate: Parasympathetic stimulation, sleep, decreased body temperature, and certain drugs (e.g., beta-blockers).

Heart Sounds

  • S1 ("Lubb"): Sound of mitral and tricuspid valve closure, marking the start of ventricular systole. Heard loudest at the apex of the heart.
  • S2 ("Dubb"): Sound of pulmonic and aortic valve closure, marking the end of ventricular systole. Heard loudest at the base of the heart.

The Cardiac Cycle

  • The cardiac cycle includes one systole-diastole sequence, lasting approximately 0.8 seconds.
  • Atrial systole: Blood moves from atria to ventricles.
  • Ventricular systole: Blood is pumped to the lungs (right ventricle) and the rest of the body (left ventricle).
  • Atrial diastole: Blood enters atria from veins.
  • Ventricular diastole: Blood enters ventricles from atria.

The Cardiac Output

  • Cardiac output is the amount of blood pumped by each ventricle per minute (approximately 5.5 liters/minute).
  • Stroke volume is the amount of blood pumped by each ventricle per beat (approximately 80 milliliters).
  • Cardiac output= heart rate × stroke volume.

Factors Affecting Cardiac Output

  • Increased cardiac output: Sympathetic stimulation.
  • Decreased cardiac output: Parasympathetic stimulation.
  • Catecholamines and thyroxin increase cardiac output.

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