Intro to The Human Genome

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Questions and Answers

What is the approximate size of the human genome in terms of base pairs?

  • 32 billion
  • 3.2 million
  • 32 million
  • 3.2 billion (correct)

How many chromosomes compose the human genome (haploid)?

  • 24
  • 22
  • 46
  • 23 (correct)

What percentage of the human genome is currently believed to code for proteins?

  • Approximately 50%
  • Approximately 80%
  • Approximately 20% (correct)
  • Approximately 99%

Which of the following describes the primary role of functional non-protein-coding genes?

<p>Regulation of gene expression and protein binding. (A)</p> Signup and view all the answers

What was the main conclusion of the ENCODE project regarding the human genome?

<p>A significant portion of the human genome is involved in regulatory activities. (A)</p> Signup and view all the answers

Which molecule encodes the human genome?

<p>DNA (D)</p> Signup and view all the answers

How does the activity of functional non-protein-coding genes vary?

<p>Their activity is specific to certain cell types. (A)</p> Signup and view all the answers

If a certain segment of the human genome does NOT code for any protein, what other functions might it have?

<p>It can regulate the expression of other genes. (B)</p> Signup and view all the answers

Imagine a drug that targets a specific functional non-protein-coding gene to alter its activity. What would be the MOST likely outcome?

<p>A change in the regulation of other genes. (D)</p> Signup and view all the answers

The human genome consists of both protein-coding and non-protein-coding regions. What proportion is non-protein-coding?

<p>Around 80% (A)</p> Signup and view all the answers

<h1>=</h1> <h1>=</h1> Signup and view all the answers

Flashcards

Human Genome

The complete set of nucleic acid sequences for humans, consisting of 3.2 billion base pairs.

Location of Human Genome

DNA within the 23 chromosomes.

Functional Non-Protein-Coding Genes

Regions of the human genome that do not code for proteins but have roles such as binding proteins or regulating gene expression.

ENCODE Project

A multinational project that revealed approximately 80% of the human genome does not code for proteins.

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Study Notes

  • The human genome comprises the complete set of nucleic acid sequences in humans, totaling 3.2 billion base pairs
  • It is encoded as DNA within 23 chromosomes (haploid)
  • The Encyclopedia of DNA Elements (ENCODE) project found that approximately 80% of the human genome does not code for proteins
  • The 80% allows for protein binding or regulation of gene expression, specific to cell type
  • The 80% are known as functional non-protein-coding genes

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