Intravenous Immunoglobulin (IVIG): Indications and Mechanisms of Action

A contraindication for vaccines is a rare condition in a recipient that increases the risk for a serious adverse reaction.

The only contraindication applicable to all vaccines is a history of a mild allergic reaction after a prior dose of vaccine.

A precaution indicates a condition in the recipient that may decrease the risk of a serious adverse reaction.

Immune globulins are antibodies synthesized by T lymphocytes.

Passive immunization with immune globulin is indicated when an individual with a low risk of exposure is exposed to an agent and there is inadequate time for active immunization.

Immune globulin contains antibodies that weaken the immune system.

Active immunization is preferred over passive immunization when there is sufficient time for vaccination before exposure to a disease.

Immunoglobulins constitute the basis of the cellular immune response.

Precautions in vaccination are typically related to mild conditions that do not impact the immune response.

Passive immunization with immune globulin may be used when a disease is already present and requires treatment with antibodies.