Intravenous Amino Acid Regimens Quiz

Choose a study mode

Play Quiz

Study Flashcards

Spaced Repetition

Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following is a constraint for amino acids in peripheral vein delivery?

Insolubility of tyrosine (correct)
High levels of phenylalanine
Low content of N-acetyltyrosine
Oxidation of cysteine to cystine

What is the purpose of giving a precursor that is more soluble than tyrosine?

To prevent cysteine oxidation
To enhance protein synthesis
To promote nitrogen retention
To address tyrosine insolubility (correct)

What is the percentage of nitrogen intake retained by pigglets?

50%
66%
70% (correct)
101%

What is the body weight gain of young piglets fed a protein deficient diet?

15% (C) Signup and view all the answers

Explain the challenges associated with delivering amino acids to peripheral veins and bypassing liver metabolism. What are the constraints for amino acids in this context?

The challenges include constraints such as solubility and stability of amino acids, with some amino acids being insoluble (e.g., tyrosine) and unstable (e.g., glutamine). Additionally, bypassing liver metabolism and splanchnic control poses significant constraints for amino acids in this context. Signup and view all the answers

How can the challenges of tyrosine insolubility and transient hyperphenylalaninemia be addressed when designing the optimal amino acid profile for intravenous regimens?

The challenges of tyrosine insolubility and transient hyperphenylalaninemia can be addressed by providing precursors that are more soluble than tyrosine, such as N-acetyltyrosine, and by ensuring the appropriate balance of phenylalanine and tyrosine to support protein synthesis and nitrogen retention. Signup and view all the answers

What is the relationship between nitrogen intake and weight gain in piglets, and what implications does this have for their diet?

The text suggests that 100% retention of nitrogen intake leads to more weight gain, while 0% retention leads to no weight gain. This implies that nitrogen intake is crucial for weight gain in piglets, and optimizing their diet to retain nitrogen is important for their growth. Signup and view all the answers

What are the potential implications of adding phenylalanine to see tyrosine specifically in piglets, and why is this approach not ideal for infants?

Adding phenylalanine to see tyrosine specifically could lead to effective utilization, but this method is expensive. Additionally, it may not be the ideal solution for infants as they may not be able to metabolize the extra phenylalanine faster. Signup and view all the answers