Podcast
Questions and Answers
Why should NOVOLIN® R be drawn into the syringe before NOVOLIN® N when mixing?
Why should NOVOLIN® R be drawn into the syringe before NOVOLIN® N when mixing?
What characteristic should NOVOLIN® N have after proper resuspension?
What characteristic should NOVOLIN® N have after proper resuspension?
A patient reports that they see small, clear particles in their NOVOLIN® N vial after resuspension. What should they do?
A patient reports that they see small, clear particles in their NOVOLIN® N vial after resuspension. What should they do?
A patient is preparing a mixed dose of NOVOLIN® N and NOVOLIN® R. After drawing both insulins into the syringe, how long can they wait before administering the injection?
A patient is preparing a mixed dose of NOVOLIN® N and NOVOLIN® R. After drawing both insulins into the syringe, how long can they wait before administering the injection?
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What is the recommended method for resuspending NOVOLIN® N in a vial before use?
What is the recommended method for resuspending NOVOLIN® N in a vial before use?
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A patient on once-daily NPH insulin at bedtime experiences nocturnal hypoglycemia. What is the most appropriate adjustment to the insulin regimen?
A patient on once-daily NPH insulin at bedtime experiences nocturnal hypoglycemia. What is the most appropriate adjustment to the insulin regimen?
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A patient is prescribed Humulin N U-100. What is the recommended initial subcutaneous dosage for an insulin-naive patient with type 2 diabetes?
A patient is prescribed Humulin N U-100. What is the recommended initial subcutaneous dosage for an insulin-naive patient with type 2 diabetes?
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A patient is prescribed Humulin R U-500. Which of the following instructions is crucial for the safe administration of this medication?
A patient is prescribed Humulin R U-500. Which of the following instructions is crucial for the safe administration of this medication?
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When should Humulin R U-500 be administered in relation to meal times?
When should Humulin R U-500 be administered in relation to meal times?
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A patient using the Humulin R U-500 KwikPen needs to administer 125 units of insulin. How should the dose be dialed on the pen?
A patient using the Humulin R U-500 KwikPen needs to administer 125 units of insulin. How should the dose be dialed on the pen?
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What visual characteristic is acceptable for Novolin N before administration?
What visual characteristic is acceptable for Novolin N before administration?
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A patient requires more than 200 units of insulin per day. Which insulin formulation is most appropriate for this patient?
A patient requires more than 200 units of insulin per day. Which insulin formulation is most appropriate for this patient?
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When initiating insulin therapy with Humulin N for a patient with type 2 diabetes, what is the most important instruction to provide regarding dose adjustments?
When initiating insulin therapy with Humulin N for a patient with type 2 diabetes, what is the most important instruction to provide regarding dose adjustments?
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Flashcards
NOVOLIN® N
NOVOLIN® N
A type of insulin used in type 1 diabetes treatment, mixed with short-acting insulin.
Mixing Insulins
Mixing Insulins
When using NOVOLIN® N with NOVOLIN® R, draw NOVOLIN® R first.
Resuspension of NOVOLIN® N
Resuspension of NOVOLIN® N
NOVOLIN® N must be resuspended before use to ensure proper dosing.
Resuspension Method for Vial
Resuspension Method for Vial
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Inspection Before Use
Inspection Before Use
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NPH Insulin
NPH Insulin
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Humulin N
Humulin N
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Dosage Adjustment for NPH
Dosage Adjustment for NPH
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Humulin R (U-500)
Humulin R (U-500)
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Administration of Humulin R
Administration of Humulin R
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U-500 Syringe Usage
U-500 Syringe Usage
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Humulin R U-100
Humulin R U-100
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Study Notes
Intermediate Acting Insulin (NPH)
- NPH insulin (also called Isophane insulin) is a basal insulin, typically dosed twice daily, and added to oral medications.
- If nocturnal hypoglycemia occurs with once-daily NPH, split the dose (e.g., ⅔ in the morning, ⅓ at bedtime).
- Inspect NPH visually before use; it should be uniformly cloudy, without particulate matter. Discard if particulate matter is present.
Humulin N (U-100)
- Available in 3mL and 10mL vials, and 3mL pens.
- For Type 2 diabetes (SC dosage for insulin-naive): 10 units subcutaneously once daily, or 0.1-0.2 units/kg/day once a day initially.
- Increase dosage by 2 units every 3 days until target fasting plasma glucose is reached without hypoglycemia. Reduce by 10-20% if hypoglycemia occurs.
Humulin R (U-500) (Regular Insulin)
- Concentrated form of regular human insulin (500 units/mL), acting as intermediate-acting due to slower peak and longer duration.
- Available in 3mL pens (1500 units) and 20mL vials (10,000 units).
- Intended for individuals needing >200 units per day.
- Use only if the solution is clear and colorless.
- Administer subcutaneously 30 minutes before meals (thigh, upper arm, abdomen, or buttocks).
- Do not mix or dilute with other insulins.
- Use U-500 insulin syringe for vials; do not perform dose conversion.
- KwikPen dials in 5 unit increments (max 300 units). Do not convert doses.
Novolin N (U-100)
- Administered once or twice daily.
- Use only if the solution is cloudy/milky.
- Usually part of regimens including short-acting insulin in Type 1 diabetes.
- Can be mixed with Novolin R. Mix Novolin R first, then Novolin N; inject immediately after mixing.
- Suspend the solution immediately before use (rolling the vial horizontally 10 times or moving the FlexPen up and down 20 times until uniformly cloudy).
- Inspect for discoloration or particulate matter before use; discard if present.
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Description
This quiz covers the essential aspects of intermediate acting insulins, including NPH, Humulin N, and Humulin R. It highlights dosing guidelines, identification of insulins, and management of potential hypoglycemia. Test your knowledge on the characteristics and proper administration of these insulins.
