The Cytoskeleton: Actin, Microtubules, and Intermediate Filaments
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Questions and Answers

What is the main function of the cytoskeleton?

  • Energy production
  • Cell rigidity (correct)
  • Protein synthesis
  • Waste excretion
  • Which proteins are associated with actin in the reversible manner?

  • Enzymes
  • Lipids
  • Profilin (correct)
  • Hormones
  • What induces the polymerization of actin filaments?

  • ATP and Mg2+ solutions (correct)
  • Low concentrations of Ca2+
  • Low pH environment
  • High concentrations of Na+ and K+
  • What is the diameter of actin microfilaments?

    <p>~ 8 nm</p> Signup and view all the answers

    What carries two binding sites allowing its attachment to other protomers of actin?

    <p>G-actin</p> Signup and view all the answers

    What is the diameter of a microtubule?

    <p>25 nm</p> Signup and view all the answers

    What is the function of microtubules in mitosis?

    <p>Movement of chromosomes to form the mitotic spindle</p> Signup and view all the answers

    What are MTOCs responsible for in the cell?

    <p>Nucleation of microtubules</p> Signup and view all the answers

    What is the composition of tubulin?

    <p>Heterodimer</p> Signup and view all the answers

    What type of motor proteins are involved in organelles and vesicles movement along microtubules?

    <p>Kinesin &amp; dynein</p> Signup and view all the answers

    Study Notes

    Cytoskeleton Function

    • Provides mechanical support, shape, and movement to the cell

    Actin Microfilaments

    • Associated with proteins such as profilin, vinculin, and α-actinin in a reversible manner
    • Polymerization is induced by ATP and can be regulated by proteins like Arp2/3 complex
    • Diameter of actin microfilaments: approximately 7 nm
    • Actin monomers carry two binding sites, allowing attachment to other protomers of actin

    Microtubules

    • Diameter: approximately 25 nm
    • Play a crucial role in mitosis, particularly in the separation of chromosomes
    • Microtubule-Organizing Centers (MTOCs) are responsible for microtubule formation and organization in the cell
    • Composed of tubulin, a heterodimer of α-tubulin and β-tubulin
    • Involve dynein and kinesin motor proteins in the movement of organelles and vesicles along microtubules

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    Description

    Test your knowledge about the cytoskeleton, a complex network of proteins in the cytoplasm, by identifying the functions and components of actin microfilaments, microtubules, and intermediate filaments.

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