The Cytoskeleton: Actin, Microtubules, and Intermediate Filaments
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Questions and Answers

What is the main function of the cytoskeleton?

  • Energy production
  • Cell rigidity (correct)
  • Protein synthesis
  • Waste excretion

Which proteins are associated with actin in the reversible manner?

  • Enzymes
  • Lipids
  • Profilin (correct)
  • Hormones

What induces the polymerization of actin filaments?

  • ATP and Mg2+ solutions (correct)
  • Low concentrations of Ca2+
  • Low pH environment
  • High concentrations of Na+ and K+

What is the diameter of actin microfilaments?

<p>~ 8 nm (D)</p> Signup and view all the answers

What carries two binding sites allowing its attachment to other protomers of actin?

<p>G-actin (B)</p> Signup and view all the answers

What is the diameter of a microtubule?

<p>25 nm (A)</p> Signup and view all the answers

What is the function of microtubules in mitosis?

<p>Movement of chromosomes to form the mitotic spindle (A)</p> Signup and view all the answers

What are MTOCs responsible for in the cell?

<p>Nucleation of microtubules (A)</p> Signup and view all the answers

What is the composition of tubulin?

<p>Heterodimer (C)</p> Signup and view all the answers

What type of motor proteins are involved in organelles and vesicles movement along microtubules?

<p>Kinesin &amp; dynein (B)</p> Signup and view all the answers

Study Notes

Cytoskeleton Function

  • Provides mechanical support, shape, and movement to the cell

Actin Microfilaments

  • Associated with proteins such as profilin, vinculin, and α-actinin in a reversible manner
  • Polymerization is induced by ATP and can be regulated by proteins like Arp2/3 complex
  • Diameter of actin microfilaments: approximately 7 nm
  • Actin monomers carry two binding sites, allowing attachment to other protomers of actin

Microtubules

  • Diameter: approximately 25 nm
  • Play a crucial role in mitosis, particularly in the separation of chromosomes
  • Microtubule-Organizing Centers (MTOCs) are responsible for microtubule formation and organization in the cell
  • Composed of tubulin, a heterodimer of α-tubulin and β-tubulin
  • Involve dynein and kinesin motor proteins in the movement of organelles and vesicles along microtubules

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Description

Test your knowledge about the cytoskeleton, a complex network of proteins in the cytoplasm, by identifying the functions and components of actin microfilaments, microtubules, and intermediate filaments.

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