Questions and Answers
What are some other names for NPH insulin?
What type of insulin is NPH insulin?
Intermediate acting
What does intermediate acting mean?
A little bit longer onset time and longer peak and duration than regular insulin.
What is the peak time for NPH insulin?
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What is the duration of NPH insulin?
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What are some contraindications for NPH insulin?
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What is the action of NPH insulin?
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What are the indications for the use of NPH insulin?
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What is the route of administration for NPH insulin?
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What is a basal dose?
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Can you mix NPH insulin with other insulins?
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What should be monitored when using NPH insulin?
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What are nursing considerations when administering NPH insulin?
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How long are vials of insulin good for?
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How long are insulin pens good for?
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What is the recommended dose of NPH insulin?
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Ginseng may increase the effect of insulin.
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Study Notes
NPH Insulin Overview
- Also known as Humulin N and Novolin N.
- Classified as an intermediate-acting insulin with an onset of 1 to 1.5 hours.
Characteristics of NPH Insulin
- Intermediate acting indicates a prolonged onset time, peak, and duration compared to regular insulin.
- Peak action occurs between 4 to 12 hours after administration.
- Average duration of action is approximately 24 hours.
Contraindications and Cautions
- Contraindicated in patients with hypoglycemia and hypokalemia due to potential cardiac complications.
- Use with caution in individuals with hepatic or renal impairment.
Mechanism of Action
- Facilitates glucose uptake in muscle and fat cells.
- Inhibits liver glucose production and fat/protein breakdown, promoting blood glucose utilization for energy.
Indications for Use
- Primarily prescribed for hyperglycemia in both Type 1 and Type 2 diabetes.
- Effective in the management of diabetic ketoacidosis.
Administration Routes
- Administered via subcutaneous injection.
Role as Basal Insulin
- Functions as a basal dose, maintaining background insulin levels throughout the day due to its extended duration.
Mixing Instructions
- Can be mixed with regular insulin.
- Always follow the sequence: clear (regular) before cloudy (NPH).
Monitoring Parameters
- Regular monitoring of glucose levels, potassium, and HbA1C is essential.
- Be aware of potential antibody development that may react to human insulin.
Nursing Considerations
- Increase monitoring frequency during stress, acute illness, or when there are changes in diet or exercise levels.
Shelf Life of Insulin
- Open vials of insulin remain stable for 31 days.
- Insulin pens are effective for up to 14 days after opening.
Dosage Guidelines
- Typical dosing ranges from 0.5 to 1 unit/kg/day, usually divided into two doses to ensure consistent basal insulin levels.
Side Effects and Interactions
- Similar side effects and therapeutic effects as other types of insulin.
- Caution advised with ginseng, which may enhance insulin effectiveness and increase the risk of hypoglycemia.
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Description
Test your knowledge of NPH insulin with these flashcards. Learn about its other names, onset times, and characteristics as an intermediate-acting insulin. Perfect for students or healthcare professionals looking to solidify their understanding of this important medication.
