Integumentary System Overview
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Questions and Answers

What is the primary cation in intracellular fluid (ICF)?

  • Cl-
  • K+ (correct)
  • Ca2+
  • Na+

Which mechanism is NOT directly targeted by Atrial Natriuretic Peptide (ANP) to decrease blood pressure?

  • Inhibiting ADH release
  • Stimulating ADH release (correct)
  • Inhibiting renin release
  • Inhibiting aldosterone release

Which of the following accurately describes the relationship between blood pressure and Atrial Natriuretic Peptide (ANP)?

  • ANP has no effect on blood pressure.
  • ANP decreases blood volume and pressure. (correct)
  • ANP decreases blood volume but increases blood pressure.
  • ANP increases blood volume and pressure.

What primarily stimulates hypothalamic osmoreceptors?

<p>Increased ECF osmolality (B)</p> Signup and view all the answers

Which of the following is true regarding extracellular fluid (ECF)?

<p>It consists of interstitial fluid and plasma. (A)</p> Signup and view all the answers

Which ion is primarily associated with extracellular fluid (ECF)?

<p>Na+ (D)</p> Signup and view all the answers

What effect does the renin-angiotensin-aldosterone system (RAAS) have on blood pressure?

<p>It increases blood pressure through vasoconstriction. (B)</p> Signup and view all the answers

What is a characteristic of non-electrolytes in body fluids?

<p>They do not dissociate in water. (A)</p> Signup and view all the answers

What is the primary function of ADH in the kidneys?

<p>To facilitate water reabsorption (B)</p> Signup and view all the answers

Which hormone is part of the Renin-Angiotensin-Aldosterone System (RAAS) and increases blood pressure?

<p>Aldosterone (B)</p> Signup and view all the answers

What physiological response occurs when blood osmolality increases?

<p>Release of ADH (D)</p> Signup and view all the answers

During which phase of the menstrual cycle does the endometrium rebuild?

<p>Proliferative phase (B)</p> Signup and view all the answers

What occurs in the body when plasma sodium (Na+) levels increase?

<p>Increased levels of ANP to decrease blood volume (B)</p> Signup and view all the answers

What is the main consequence of aldosterone's action in the kidneys?

<p>Increase in salt retention (B)</p> Signup and view all the answers

Which event occurs first in the uterine cycle?

<p>Menses phase (A)</p> Signup and view all the answers

What triggers thirst and water absorption in response to high blood osmolality?

<p>Release of ADH (C)</p> Signup and view all the answers

What is the role of POMC/CART neurons in appetite regulation?

<p>They decrease appetite. (B)</p> Signup and view all the answers

Which hormone is most closely associated with long-term regulation of food intake?

<p>Leptin (B)</p> Signup and view all the answers

Which mechanism helps to cool the body when temperature rises?

<p>Vasodilation of skin blood vessels (C)</p> Signup and view all the answers

What process occurs to maintain body temperature when it falls?

<p>Activation of heat preservation mechanisms (B)</p> Signup and view all the answers

How is the Total Metabolic Rate calculated?

<p>BMR + Thermal Effect of Food (TEF) + Physical Activity (PA) (A)</p> Signup and view all the answers

What is the primary contributor to heat production during exercise?

<p>Skeletal muscle activity (C)</p> Signup and view all the answers

Which of the following has the greatest effect on basal metabolic rate (BMR)?

<p>Thyroxine levels (C)</p> Signup and view all the answers

Which mechanism does the hypothalamus activate when body temperature decreases?

<p>Heat preservation mechanisms (B)</p> Signup and view all the answers

Flashcards

Intracellular Fluid (ICF)

The fluid inside body cells; comprises about 1/3 of total body water.

Extracellular Fluid (ECF)

Fluid outside of body cells, subdivided into interstitial fluid (surrounding cells) and plasma (in blood vessels).

Interstitial Fluid

The fluid that surrounds cells in tissues.

Plasma

The liquid component of blood; contains water, proteins, and dissolved substances.

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Electrolytes

Ions that dissociate in water; crucial for many body functions.

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Kidney Urine Production

The kidneys can produce a minimum of 500 ml/day or up to 1600-2000 ml/day of urine.

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Hypothalamic Osmoreceptors

These receptors sense changes in ECF osmolality (salt concentration).

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ANP (Atrial Natriuretic Peptide)

A hormone that lowers blood pressure by increasing water and salt excretion, and vasodilation.

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Satiety signals

Signals that tell the body it's full and reduce appetite.

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Hypothalamus (appetite)

Brain region that regulates appetite through POMC/CART neurons.

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Basal Metabolic Rate

The minimum energy expenditure for basic life functions at rest.

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Thermoregulation

The body's process of maintaining a stable internal temperature.

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Heat Release Mechanisms

Body reactions to reduce internal temperature.

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Heat Preservation Mechanisms

Body reactions to maintain internal temperature.

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Hormonal factor (BMR)

Thyroxine plays a key role in basal metabolic rate.

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Sweating; purpose

Main function is to cool the body by evaporating water.

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ADH function

Antidiuretic hormone (ADH) regulates blood pressure and volume by controlling water reabsorption in the kidneys. It prevents dehydration by inhibiting water loss.

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RAAS system effect

The Renin-Angiotensin-Aldosterone System (RAAS) increases blood pressure by promoting salt reabsorption in the kidneys. This causes water retention, which also increases blood volume and pressure.

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High blood osmolality response

Increased blood osmolality triggers thirst and the release of ADH, leading to increased water reabsorption in the kidneys.

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Low blood osmolality response

Decreased blood osmolality inhibits thirst and reduces ADH release, causing the kidneys to excrete more dilute urine.

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Water and Sodium relationship

Water follows sodium. Sodium levels significantly affect body water distribution, ECF volume, and blood pressure.

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Aldosterone's function

Aldosterone, a steroid hormone, increases blood pressure by promoting salt retention in the kidneys, which leads to water retention.

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High Blood Pressure Response

Increased blood pressure or sodium levels stimulate ANP, leading to decreased blood volume to restore normal pressure.

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Uterine Cycle - Menses

The uterine cycle's menses phase involves shedding of the uterine lining.

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Study Notes

Integumentary System

  • Skin layers: epidermis, dermis, and hypodermis. The dermis is vascularized.
  • Epidermis contains four cell types: keratinocytes, melanocytes, dendritic cells, and tactile epithelial cells.
  • Epidermal layers: stratum basale (10-25% melanocytes), stratum corneum (dead keratinocytes), stratum lucidum (thick skin only), stratum spinosum (prickle cell layer with dendritic cells), stratum granulosum (glycolipids).
  • Dermis layers: reticular layer and papillary layer. They differ in structure and function.
  • Skin color factors: melanin (dark/medium brown), carotene (yellowish), and hemoglobin (reddish in fair skin).
  • Sweat glands: eccrine (everywhere, abundant on palms, soles, forehead, and contains watery secretion) and apocrine (axillary and genital areas, contains fatty substances and proteins, leading to body odor).
  • Epidermis is the outer layer, and the hypodermis is not a true part of the skin.

Energy Balance & Thermoregulation

  • Factors stimulating hunger and appetite: ghrelin.
  • Satiety signals: POMC/CART activation, CCK, insulin, nutrient signals (glucose, amino acids, fatty acids), and neural signals from the GI tract.
  • Hormone for long-term food intake regulation: leptin.
  • Basal metabolic rate components: BMR (70%), TEF (10%), and physical activity (20%).

Body Fluid and Electrolyte Balance

  • Body water compartments: intracellular fluid (ICF) and extracellular fluid (ECF), ECF is further divided into interstitial fluid (IF) and plasma.
  • ICF contains fluid inside the cells. ECF surrounds the cells.
  • Electrolytes: ions that dissociate in water (Na+, Cl-, K+, HPO42-).
  • Nonelectrolytes: do not dissociate in water (glucose, lipids, creatinine, urea).

Hormonal Regulation of Fluid Balance

  • Hypothalamic osmoreceptors detect changes to blood pressure, volume, and ECF osmolality.
  • Antidiuretic hormone (ADH): increases water reabsorption in kidneys.
  • Aldosterone: increases salt reabsorption in kidneys, leading to increased water retention.
  • Atrial natriuretic peptide (ANP): reduces blood volume and blood pressure if levels are high by increasing sodium and water loss via kidneys.

Female and Male Reproduction

  • Uterine cycle phases: menstruation, proliferative phase, and secretory phase.
  • Ovarian cycle phases: follicular phase (estrogen peaks) and luteal phase (progesterone peaks), followed by ovulation.
  • Female ages related to reproductive end: around ages 40-50.

Fetal Development

  • Timing of fertilization and implantation: sperm can be present before ovulation, fertilization occurs within the fallopian tube, and implantation happens in the uterus.
  • Embryo development: stages from fertilization, morula, blastocyst, to implantation.

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Description

Test your knowledge on the integumentary system, including the structure and functions of the skin layers, the various cell types present in the epidermis, and the factors affecting skin color. This quiz also covers sweat glands and thermoregulation aspects related to the skin.

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