Hamdan-Endocrine Physiology
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Questions and Answers

What can happen if an acidophilic tumor occurs after adolescence?

  • Person may develop panhypopituitarism
  • Bones cannot grow taller but can become thicker (correct)
  • Person may develop hyperglycemia
  • Person can grow taller

What is a common effect of acromegaly on the lower jaw?

  • It slants forward (Prognathism) (correct)
  • It becomes smaller
  • It retracts backward
  • It becomes narrower

In acromegaly, what can lead to a hunched back?

  • Enlargement in the hands and feet
  • Changes in the vertebrae causing kyphosis (correct)
  • Thickening of fingers
  • Enlargement in the nose

What is a notable effect of acromegaly on the nose?

<p>It increases to as much as twice normal size (A)</p> Signup and view all the answers

What happens to the hands in acromegaly?

<p>They almost double in size (D)</p> Signup and view all the answers

What is a common effect of acromegaly on the forehead?

<p>It slants forward due to excess development of supraorbital ridges (B)</p> Signup and view all the answers

What is a characteristic effect of acromegaly on feet size?

<p>Feet require size 14 or larger shoes (D)</p> Signup and view all the answers

What causes enlargement in the bones in acromegaly?

<p>Fusion of epiphyses with shafts after adolescence (D)</p> Signup and view all the answers

In which nuclei is ADH primarily formed?

<p>Supraoptic nuclei (B)</p> Signup and view all the answers

What happens if an acidophilic tumor occurs after the epiphyses of the long bones have fused?

<p>The person cannot grow taller (A)</p> Signup and view all the answers

Where are the posterior pituitary hormones synthesized?

<p>Cell bodies of supraoptic and paraventricular nuclei (C)</p> Signup and view all the answers

What is oxytocin primarily formed in?

<p>Paraventricular nuclei (B)</p> Signup and view all the answers

How many amino acids are in oxytocin?

<p>9 (D)</p> Signup and view all the answers

What happens if the pituitary stalk is cut above the pituitary gland but the hypothalamus is left intact?

<p>Hormone secretion decreases transiently (B)</p> Signup and view all the answers

"Carrier" proteins called neurophysins help transport the hormones down to where?

<p>&quot;Carrier&quot; proteins transport them to nerve endings in the posterior pituitary (C)</p> Signup and view all the answers

"If a tumor occurs post-adolescence and before bone fusion, what growth changes may occur?

<p>&quot;No height changes but thicker bones and continuous soft tissue growth&quot; (C)</p> Signup and view all the answers

What is the gold standard test for assessing growth hormone reserve?

<p>Insulin-induced hypoglycemia (insulin tolerance test) (A)</p> Signup and view all the answers

When growth hormone is administered directly into the blood of an animal, what happens to the rate of endogenous growth hormone secretion?

<p>It decreases (A)</p> Signup and view all the answers

What is uncertain regarding the feedback mechanism for growth hormone secretion?

<p>Both a and b (D)</p> Signup and view all the answers

In the disease kwashiorkor, which treatment was effective in lowering growth hormone concentration?

<p>Protein treatment (C)</p> Signup and view all the answers

Which condition is a more potent stimulator of growth hormone secretion under acute conditions?

<p>Hypoglycemia (B)</p> Signup and view all the answers

In chronic conditions, what does growth hormone secretion seem to correlate more with?

<p>The degree of cellular protein depletion (D)</p> Signup and view all the answers

What is the condition characterized by the production of large quantities of growth hormone?

<p>Gigantism (B)</p> Signup and view all the answers

In the condition of gigantism, when does the rapid growth of body tissues occur?

<p>Before adolescence (D)</p> Signup and view all the answers

Where is the thyroid gland located?

<p>Inferior to larynx and anterior to the trachea (C)</p> Signup and view all the answers

Which hormone(s) does the thyroid follicle produce?

<p>Thyroxine (T4) and Triiodothyronine (T3) (C)</p> Signup and view all the answers

What is the primary function of the hormones T4 and T3?

<p>Increase basal metabolic rate (BMR) and stimulate protein synthesis (D)</p> Signup and view all the answers

Which cells in the thyroid gland produce calcitonin?

<p>Parafollicular cells or C cells (D)</p> Signup and view all the answers

What is the primary function of calcitonin?

<p>Lowers blood calcium levels by inhibiting bone resorption (A)</p> Signup and view all the answers

What percentage of the thyroid hormones secreted is thyroxine (T4)?

<p>93% (C)</p> Signup and view all the answers

How is iodine deficiency prevented in the general population?

<p>By consuming iodized table salt (B)</p> Signup and view all the answers

What is the first stage in the formation of thyroid hormones?

<p>Transport of iodides from the blood into the thyroid glandular cells and follicles (B)</p> Signup and view all the answers

What is the primary function of antidiuretic hormone (ADH)?

<p>To increase water reabsorption in the kidneys (C)</p> Signup and view all the answers

Which of the following triggers the release of ADH?

<p>Increased extracellular fluid osmolarity (B)</p> Signup and view all the answers

What is the primary difference between the amino acid sequences of vasopressin and oxytocin?

<p>Vasopressin has phenylalanine and arginine, while oxytocin has isoleucine and leucine (B)</p> Signup and view all the answers

What is the primary target tissue for ADH?

<p>Kidneys (C)</p> Signup and view all the answers

Which of the following receptors are responsible for detecting changes in blood pressure and volume, which can trigger ADH release?

<p>Baroreceptors (C)</p> Signup and view all the answers

What is the role of ADH in regulating blood pressure?

<p>It causes vasoconstriction, increasing blood pressure (D)</p> Signup and view all the answers

Where are the osmoreceptors that detect changes in extracellular fluid osmolarity located?

<p>Somewhere in or near the hypothalamus (B)</p> Signup and view all the answers

What is the secondary effect of ADH on sweat glands?

<p>It decreases water loss by perspiration (B)</p> Signup and view all the answers

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