Insulin Actions and Regulation

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Questions and Answers

What is the primary mechanism by which the liver reduces the hyperglycemic effect of a high-carbohydrate meal?

  • By releasing insulin into the bloodstream
  • By stimulating the β-cells of the pancreas to secrete glucagon
  • By extracting relatively more glucose from the portal plasma than in the fasting state (correct)
  • By increasing the breakdown of glycogen into glucose

What is the threshold plasma glucose concentration that stimulates insulin release from the pancreas β-cell?

  • 5 mmol/L (correct)
  • 10 mmol/L
  • 7 mmol/L
  • 3 mmol/L

What is the effect of insulin on muscle and adipose tissue cells?

  • It inhibits the uptake of glucose into these cells
  • It enhances the entry of glucose into these cells (correct)
  • It has no effect on glucose uptake in these cells
  • It stimulates the breakdown of glycogen into glucose in these cells

What is the primary function of glucagon in carbohydrate metabolism?

<p>To stimulate the breakdown of glycogen into glucose (B)</p> Signup and view all the answers

What is the impact of insulin on glycogen synthesis?

<p>It stimulates glycogen synthesis (B)</p> Signup and view all the answers

What is the relationship between insulin and glucagon in carbohydrate metabolism?

<p>The actions of insulin and glucagon are counter-regulatory (D)</p> Signup and view all the answers

What is the effect of insulin on lipogenesis?

<p>It stimulates lipogenesis (B)</p> Signup and view all the answers

What is the role of the glucose transporter 2 in insulin release?

<p>It stimulates insulin release (A)</p> Signup and view all the answers

What is the primary source of glucose in the fasting state?

<p>Glycogenolysis (B)</p> Signup and view all the answers

What is the effect of insulin on protein synthesis?

<p>It stimulates protein synthesis (C)</p> Signup and view all the answers

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