Podcast
Questions and Answers
- Which of the following results would you predict to occur
with a mutation that changes the phosphorylatable Tyr of the
Insulin Receptor (cannot be phosphorylated)?
- Which of the following results would you predict to occur with a mutation that changes the phosphorylatable Tyr of the Insulin Receptor (cannot be phosphorylated)?
) Which of the following proteins is required for the
GLUT4 transporter to be localized on the plasma
membrane for glucose uptake
) Which of the following proteins is required for the GLUT4 transporter to be localized on the plasma membrane for glucose uptake
. When insulin binds to its receptor, all of the following
happen EXCEPT:
. When insulin binds to its receptor, all of the following happen EXCEPT:
Which second messenger signals the release of Ca++ from the
endoplasmic reticulum?
Which second messenger signals the release of Ca++ from the endoplasmic reticulum?
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- The diagram shows some biochemical
pathways in a liver cell, some of which are
reversible. Five reactions whose rate in a
certain direction can be changed by the
presence of a hormone are labelled 1 – 5.
Each number relates to the direction of
the arrow nearest to the number.
Which numbered reactions have their rate
increased in the presence of insulin?
- The diagram shows some biochemical pathways in a liver cell, some of which are reversible. Five reactions whose rate in a certain direction can be changed by the presence of a hormone are labelled 1 – 5. Each number relates to the direction of the arrow nearest to the number. Which numbered reactions have their rate increased in the presence of insulin?
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When epinephrine or glucagon bind to their receptor on the
membrane and activate the cAMP cascade, all of the following
happen EXCEPT
When epinephrine or glucagon bind to their receptor on the membrane and activate the cAMP cascade, all of the following happen EXCEPT
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What type of protein is Ras?
What type of protein is Ras?
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) Concerning the insulin receptor and the IRS protein:
) Concerning the insulin receptor and the IRS protein:
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) Which of the following enzymes is activated by cyclic AMP,
passing on the hormonal signal?
) Which of the following enzymes is activated by cyclic AMP, passing on the hormonal signal?
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Which pathway for glycogen breakdown in the liver would
prevent the cell from breaking down glycogen in response
to epinephrine
Which pathway for glycogen breakdown in the liver would prevent the cell from breaking down glycogen in response to epinephrine
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Study Notes
Insulin Receptor and Signaling
- A mutation that changes the phosphorylatable Tyr of the Insulin Receptor prevents phosphorylation.
- Insulin binding to its receptor triggers all events except one (to be specified).
GLUT4 Transporter and Glucose Uptake
- The presence of a specific protein is required for GLUT4 transporter localization on the plasma membrane for glucose uptake.
Second Messenger Signaling
- A specific second messenger signals the release of Ca++ from the endoplasmic reticulum.
Hormone Regulation of Biochemical Pathways
- In a liver cell, certain reactions (1-5) have their rate changed by the presence of a hormone.
- Insulin increases the rate of specific reactions (to be specified).
Epinephrine and Glucagon Signaling
- When epinephrine or glucagon bind to their receptor, all events occur except one (to be specified).
- The cAMP cascade is activated by epinephrine or glucagon binding.
Ras Protein and Signaling
- Ras is a type of protein involved in signaling pathways.
cAMP-activated Enzymes
- A specific enzyme is activated by cyclic AMP, passing on the hormonal signal.
Glycogen Breakdown Regulation
- A specific pathway for glycogen breakdown in the liver prevents the cell from breaking down glycogen in response to epinephrine.
- Insulin and IRS protein interactions play a crucial role in glycogen metabolism regulation.
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Description
Test your knowledge on cell signaling pathways with this quiz! Identify the different types of signaling proteins including tyrosine kinase, monomeric GTPase switch protein, serine-threonine kinase, and G protein coupled receptor. Sharpen your understanding of how these proteins function in cellular communication and their roles in various signaling pathways.