Innate Immunity to Parasites Quiz
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Questions and Answers

What is molecular mimicry and how can it lead to immune responses against self antigens?

Molecular mimicry is when antiviral immunity causes immune responses against self antigens.

How do viruses evade the immune system through antigenic drift and shift?

Viruses can alter their antigens through point mutations (antigenic drift) or reassortment of RNA (antigenic shift).

What is the role of class I MHC-associated presentation in immune response to viruses?

Class I MHC-associated presentation is important for recognition and killing of virus-infected cells by cytotoxic T lymphocytes (CTLs).

How do poxviruses evade the immune response?

<p>Poxviruses encode molecules that bind to cytokines like IFN-γ, TNF, IL-1, IL-18, and chemokines.</p> Signup and view all the answers

What is the significance of HIV infection causing PD-1-mediated T cell unresponsiveness?

<p>HIV can induce T cell unresponsiveness through PD-1 signaling, leading to immune evasion.</p> Signup and view all the answers

Give an example of how viruses may infect and affect immunocompetent cells.

<p>HIV infects and either kills or inactivates immunocompetent cells.</p> Signup and view all the answers

What is parasitic infection, and what are the different types of parasites involved?

<p>Parasitic infection refers to infection with protozoa, helminths, and ectoparasites like ticks and mites.</p> Signup and view all the answers

How do parasites like protozoa develop resistance mechanisms?

<p>Protozoa can develop resistance mechanisms through genetic mutations or alterations in their surface antigens.</p> Signup and view all the answers

What defense mechanisms do helminthic parasites employ to survive host immune responses?

<p>Helminthic parasites use strategies like immune modulation, antigen masking, and tissue invasion to evade host immunity.</p> Signup and view all the answers

Explain the injurious effects of immunity during parasitic infections.

<p>Immune responses to parasites can cause tissue damage, inflammation, and allergic reactions.</p> Signup and view all the answers

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