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Questions and Answers
What is the primary function of cytotoxic T-cells?
What is the primary function of cytotoxic T-cells?
- To produce antibodies against pathogens
- To secrete proteins that assist other immune cells
- To recognize and kill virus-infected cells (correct)
- To deactivate the immune response
Where do T-cells mature in the body?
Where do T-cells mature in the body?
- The bone marrow
- The spleen
- The thymus (correct)
- The liver
What is the role of helper T-cells in the immune system?
What is the role of helper T-cells in the immune system?
- To inhibit the production of antibodies
- To enhance the activity of other immune cells (correct)
- To directly kill infected cells
- To create memory cells for future infections
Which type of T-cell is primarily responsible for controlling the immune response?
Which type of T-cell is primarily responsible for controlling the immune response?
Which antibody is primarily responsible for immune protection to the fetus and newborn?
Which antibody is primarily responsible for immune protection to the fetus and newborn?
What is the function of major histocompatibility complex (MHC) molecules?
What is the function of major histocompatibility complex (MHC) molecules?
What is the main role of IgA in the immune system?
What is the main role of IgA in the immune system?
Which antibody is most associated with allergic reactions?
Which antibody is most associated with allergic reactions?
What type of immune response is primarily mediated by T-cells?
What type of immune response is primarily mediated by T-cells?
What characterizes the role of IgD in the immune response?
What characterizes the role of IgD in the immune response?
Which antibody is considered the major antibody produced in response to an initial exposure to an antigen?
Which antibody is considered the major antibody produced in response to an initial exposure to an antigen?
What is a key function of mast cells activated by IgE?
What is a key function of mast cells activated by IgE?
How do T-cells contribute to the cell-mediated immune response?
How do T-cells contribute to the cell-mediated immune response?
What is the primary role of barrier defenses in the immune system?
What is the primary role of barrier defenses in the immune system?
Which cells are primarily responsible for antibody production in the humoral immune response?
Which cells are primarily responsible for antibody production in the humoral immune response?
What characterizes inflammation in the immune response?
What characterizes inflammation in the immune response?
What is a foreign antigen?
What is a foreign antigen?
Which type of antibody is the first to appear during an immune response?
Which type of antibody is the first to appear during an immune response?
What is one of the roles of the complement system in the immune response?
What is one of the roles of the complement system in the immune response?
How do B-cells become activated?
How do B-cells become activated?
Which of the following describes the function of phagocytic cells?
Which of the following describes the function of phagocytic cells?
What is a key characteristic of innate immunity?
What is a key characteristic of innate immunity?
How does adaptive immunity differ from innate immunity?
How does adaptive immunity differ from innate immunity?
What role does the innate immune system play in the overall immune response?
What role does the innate immune system play in the overall immune response?
Why might a person get sick despite following healthy precautions?
Why might a person get sick despite following healthy precautions?
Which of the following statements about adaptive immunity is true?
Which of the following statements about adaptive immunity is true?
What is the primary function of signaling from the innate immune system?
What is the primary function of signaling from the innate immune system?
What could be the consequence of not having memory cells in adaptive immunity?
What could be the consequence of not having memory cells in adaptive immunity?
Flashcards
Innate Immunity
Innate Immunity
The body's fast-acting, first line of defense against pathogens. It's non-specific and doesn't adapt or remember previous encounters.
Adaptive Immunity
Adaptive Immunity
A slower-acting immune response that develops after exposure. It is highly specific to particular pathogens and has memory, enabling quicker responses upon re-exposure.
Pathogen
Pathogen
A microorganism or substance that causes disease.
Immunity
Immunity
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Specific Features of Adaptive Immunity
Specific Features of Adaptive Immunity
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Memory Features of Adaptive Immunity
Memory Features of Adaptive Immunity
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Internal threats (immunity)
Internal threats (immunity)
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Innate Immune System's Role
Innate Immune System's Role
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Barrier Defenses
Barrier Defenses
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Internal Defenses
Internal Defenses
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What are Chemical Mediators?
What are Chemical Mediators?
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Phagocytic Cells
Phagocytic Cells
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Natural Killer Cells
Natural Killer Cells
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Inflammation: What is it?
Inflammation: What is it?
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What are Antibodies?
What are Antibodies?
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IgG
IgG
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IgA
IgA
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IgE
IgE
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IgD
IgD
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Cell-mediated immunity
Cell-mediated immunity
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What are cytotoxic cells?
What are cytotoxic cells?
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Why is cell-mediated immunity important?
Why is cell-mediated immunity important?
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What is the role of T cells?
What is the role of T cells?
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T-cells
T-cells
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MHC molecules
MHC molecules
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Cytotoxic T-cells
Cytotoxic T-cells
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Helper T-cells
Helper T-cells
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Regulatory T-cells
Regulatory T-cells
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Study Notes
Innate vs. Adaptive Immunity
- Innate immunity is a fast-acting, non-specific defense mechanism.
- It's the body's first response to infection.
- Innate responses do not change with repeated exposures.
- Innate immunity involves barrier defenses (skin, mucous membranes), internal defenses (antimicrobial proteins, phagocytic cells, inflammatory response).
- Adaptive immunity is slower but more specific, responding to specific pathogens.
- Adaptive immunity has memory to allow faster responses upon re-exposure to the same pathogen.
Immune System Components
- Innate Immunity:
- Barrier defenses (skin, mucous membranes)
- Internal defenses (phagocytic cells, natural killer cells, antimicrobial proteins, inflammatory response)
- Adaptive Immunity:
- Humoral response (antibodies produced by B cells).
- Cell-mediated response (T cells directly attacking infected cells)
Types of Cells
- Innate Immunity:
- Neutrophils: most abundant white blood cells, first responders
- Eosinophils: respond to multicellular parasites
- Basophils: release chemicals initiating inflamation
- Monocytes: develop into macrophages and dendritic cells, slower response but longer-lasting
- Lymphocytes: produce antibodies targeting specific antigens
- Adaptive Immunity:
- Cytotoxic T cells: destroy virus-infected cells
- Helper T cells: assist other immune cells
- Regulatory T cells: control the immune response, preventing autoimmune disease
Immune System Function
- Innate immunity provides an initial signal to alert the rest of the immune system.
- Pathogens and/or toxins are identified and neutralized by the immune response.
- The adaptive response is activated.
- Responses can be active or passive, natural or artificial.
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