12 Questions
Which of the following best describes the function of the complement system?
Opsonizing pathogens and inducing an inflammatory response
What triggers the activation of the complement system?
Local activation at sites of infection
How is the complement system activated?
Through a triggered-enzyme cascade
What is the role of activated complement proteins in the immune response?
Opsonizing pathogens and recruiting more phagocytes
Which protein mediates the ingestion of complement-tagged pathogens by phagocytes?
CR1
What is the main function of chemokines?
Induce directed chemotaxis in nearby responsive cells
Which cells are mainly guided by chemokines in the adaptive immune response?
Lymphocytes
What is the role of terminal complement proteins in killing certain pathogens?
Forming pores in membranes
Which type of cytokines induce responses through binding specific receptors on target cells?
TNF family cytokines
What is the function of small fragments of complement?
Stimulate increased blood flow
Which proteins are lacking on pathogen surfaces, allowing C3 to work?
DAF and CD55
What is the main role of complement activation?
Creating pores in bacterial membranes
Test your knowledge of innate immunity with this quiz covering topics such as phagocytosis by macrophages, pattern recognition, release of cytokines and chemokines, activation of complement, and the role of complement in marking pathogens for destruction. Perfect for students of immunology and anyone interested in understanding the body's initial defense mechanisms.
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