Podcast
Questions and Answers
Which molecule allows cells to adhere reversibly to the vessel wall?
Which molecule allows cells to adhere reversibly to the vessel wall?
- ICAM1
- LFA-1
- E-selectin (correct)
- CR3
Which molecules are involved in the firm attachment of rolling cells to the endothelium?
Which molecules are involved in the firm attachment of rolling cells to the endothelium?
- TNFa and LPS
- Integrins LFA-1 and CR3 (correct)
- ICAM1&2
- Histamine and C5a
Which molecule is expressed at junctions of endothelial cells and allows cells to squeeze through these junctions?
Which molecule is expressed at junctions of endothelial cells and allows cells to squeeze through these junctions?
- LFA-1
- CD31 (correct)
- E-selectin
- CR3
What triggers the conformational change in rolling cells, increasing their adhesive properties?
What triggers the conformational change in rolling cells, increasing their adhesive properties?
Which molecule is involved in the penetration of the basement membrane by producing enzymes that break down the extracellular matrix protein?
Which molecule is involved in the penetration of the basement membrane by producing enzymes that break down the extracellular matrix protein?
What is the function of C reactive protein during the acute phase response?
What is the function of C reactive protein during the acute phase response?
Which molecules contribute to the long-range effects of macrophage-produced cytokines during the acute phase response?
Which molecules contribute to the long-range effects of macrophage-produced cytokines during the acute phase response?
What is the role of chemokines in the migration of cells through tissue to the infection site?
What is the role of chemokines in the migration of cells through tissue to the infection site?
What is the function of mannose binding lectin during the acute phase response?
What is the function of mannose binding lectin during the acute phase response?
What is the role of pattern recognition receptors in the immune response?
What is the role of pattern recognition receptors in the immune response?
What is the first step in the recruitment of cells to the site of infection?
What is the first step in the recruitment of cells to the site of infection?
What is the function of P-selectin at inflammatory sites?
What is the function of P-selectin at inflammatory sites?
Which molecules are induced on the surface of the local blood vessel endothelium and on infiltrating cells during the recruitment of cells to the site of infection?
Which molecules are induced on the surface of the local blood vessel endothelium and on infiltrating cells during the recruitment of cells to the site of infection?
What enables the engulfing of bacteria and the recruitment of cells to the site of infection?
What enables the engulfing of bacteria and the recruitment of cells to the site of infection?
What is the final step in the recruitment of cells to the site of infection?
What is the final step in the recruitment of cells to the site of infection?
What is the role of cell adhesion molecules during the recruitment of cells to the site of infection?
What is the role of cell adhesion molecules during the recruitment of cells to the site of infection?
What is the function of chemokines during the recruitment of cells to the site of infection?
What is the function of chemokines during the recruitment of cells to the site of infection?
Which molecules are involved in the activation of complement during the recruitment of cells to the site of infection?
Which molecules are involved in the activation of complement during the recruitment of cells to the site of infection?
What is the consequence of the vessels being dilated at inflammatory sites?
What is the consequence of the vessels being dilated at inflammatory sites?
What is the initial step in the recruitment of cells to the site of infection?
What is the initial step in the recruitment of cells to the site of infection?