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Inhibitory Receptors in Immune Response Quiz

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Inhibitory Receptors in Immune Response Quiz

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Questions and Answers

What are the major subsets of CD4+ effector T cells?

Th1 and Treg cells

Th1 and Th2 cells (correct)

Treg and Th17 cells

Th2 and Th17 cells

How do CD8+ CTLs kill cells infected with viruses?

By releasing perforin and granzymes (correct)

By triggering phagocytosis of infected cells

By secreting cytokines to induce cell death

By inducing apoptosis through Fas-FasL interaction

What are the mechanisms by which T cells activate macrophages?

Production of tumor necrosis factor

Secretion of interleukin-4

Expression of CD40 ligand

Release of interferon-gamma (correct)

Which cytokines are associated with Th1 cells?

Interferon-gamma and IL-2 Signup and view all the answers

What are the roles of Th2 cells in defense against pathogens?

Defense against extracellular parasites Signup and view all the answers

What is the primary function of CD4+ Treg cells?

Suppression of excessive immune responses Signup and view all the answers

What is the response of macrophages that result in the killing of ingested microbes?

Enhanced production of reactive oxygen species Signup and view all the answers

How do CD4+ cells play a role in killing cells infected with viruses?

By activating CD8+ cytotoxic T lymphocytes Signup and view all the answers

Which cytokines play a role in the activation of macrophages by T cells?

Interferon-gamma and TNF-alpha Signup and view all the answers

What are the types of T lymphocyte–mediated immune reactions that eliminate microbes sequestered in phagocyte vesicles or infected host cells?

Delayed-type hypersensitivity and cytotoxic T cell response Signup and view all the answers