Inhibitory Receptors in Immune Response Quiz
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Questions and Answers

What are the major subsets of CD4+ effector T cells?

  • Th1 and Treg cells
  • Th1 and Th2 cells (correct)
  • Treg and Th17 cells
  • Th2 and Th17 cells

How do CD8+ CTLs kill cells infected with viruses?

  • By releasing perforin and granzymes (correct)
  • By triggering phagocytosis of infected cells
  • By secreting cytokines to induce cell death
  • By inducing apoptosis through Fas-FasL interaction

What are the mechanisms by which T cells activate macrophages?

  • Production of tumor necrosis factor
  • Secretion of interleukin-4
  • Expression of CD40 ligand
  • Release of interferon-gamma (correct)

Which cytokines are associated with Th1 cells?

<p>Interferon-gamma and IL-2 (D)</p> Signup and view all the answers

What are the roles of Th2 cells in defense against pathogens?

<p>Defense against extracellular parasites (C)</p> Signup and view all the answers

What is the primary function of CD4+ Treg cells?

<p>Suppression of excessive immune responses (C)</p> Signup and view all the answers

What is the response of macrophages that result in the killing of ingested microbes?

<p>Enhanced production of reactive oxygen species (B)</p> Signup and view all the answers

How do CD4+ cells play a role in killing cells infected with viruses?

<p>By activating CD8+ cytotoxic T lymphocytes (A)</p> Signup and view all the answers

Which cytokines play a role in the activation of macrophages by T cells?

<p>Interferon-gamma and TNF-alpha (C)</p> Signup and view all the answers

What are the types of T lymphocyte–mediated immune reactions that eliminate microbes sequestered in phagocyte vesicles or infected host cells?

<p>Delayed-type hypersensitivity and cytotoxic T cell response (A)</p> Signup and view all the answers

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