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Questions and Answers
What type of inhibitor is captopril, which acts on Angiotensin-converting enzyme?
What type of inhibitor is captopril, which acts on Angiotensin-converting enzyme?
- Non-competitive inhibitor
- Uncompetitive inhibitor
- Competitive inhibitor (correct)
- Allosteric inhibitor
Which type of inhibitor binds to an allosteric site separate from the active site of substrate binding?
Which type of inhibitor binds to an allosteric site separate from the active site of substrate binding?
- Uncompetitive inhibitor
- Competitive inhibitor
- Allosteric inhibitor
- Non-competitive inhibitor (correct)
What happens when a competitive inhibitor occupies the active site of an enzyme?
What happens when a competitive inhibitor occupies the active site of an enzyme?
- The enzyme is activated
- The enzyme-substrate complex is formed
- The enzyme-inhibitor complex is formed (correct)
- The substrate is converted into product
What are the four protein targets for drug action?
What are the four protein targets for drug action?
What is the mechanism of action of a uncompetitive inhibitor?
What is the mechanism of action of a uncompetitive inhibitor?
What is the result of substrate-binding in uncompetitive inhibition?
What is the result of substrate-binding in uncompetitive inhibition?
What type of inhibition occurs when an inhibitor binds to an enzyme regardless of the presence of a bound substrate?
What type of inhibition occurs when an inhibitor binds to an enzyme regardless of the presence of a bound substrate?
What is the mechanism of action of the anticancer drug fluorouracil?
What is the mechanism of action of the anticancer drug fluorouracil?
What is the process by which some drugs require enzymic degradation to become active?
What is the process by which some drugs require enzymic degradation to become active?
What is the effect of Cimetidine on liver microsomal enzymes?
What is the effect of Cimetidine on liver microsomal enzymes?
What is the result of enzymic conversion of a drug molecule to a reactive metabolite?
What is the result of enzymic conversion of a drug molecule to a reactive metabolite?
What is the role of ATP hydrolysis in ABC transporters?
What is the role of ATP hydrolysis in ABC transporters?
What is the role of transporters (carrier molecules) in cellular processes?
What is the role of transporters (carrier molecules) in cellular processes?
How do neurotransmitter transporters transport organic molecules?
How do neurotransmitter transporters transport organic molecules?
What is the effect of cocaine on Monoamine neurotransmitter uptake?
What is the effect of cocaine on Monoamine neurotransmitter uptake?
What is the function of the sodium pump (Na+/K+/ATPase)?
What is the function of the sodium pump (Na+/K+/ATPase)?
What is the function of multidrug resistance (MDR) transporters?
What is the function of multidrug resistance (MDR) transporters?
