Platelet Inhibitors Quiz
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Questions and Answers

Which type of drugs prevent blood clotting by suppressing the synthesis or function of clotting factors?

  • Anticoagulants (correct)
  • Fibrinolytics
  • Antiplatelet drugs
  • Calcium complexing agents
  • Which substance is used for anticoagulation in vitro to prevent blood clotting during investigations?

  • Fondaparinux
  • Argatroban
  • Heparin
  • Sodium citrate (correct)
  • Which type of thrombosis is often associated with myocardial infarction, stroke, and ischemia?

  • White thrombosis
  • Venous thrombosis
  • Arterial thrombosis (correct)
  • Thromboembolism
  • What can venous emboli potentially block in the body's circulation?

    <p>Arterioles in the lung</p> Signup and view all the answers

    What is the primary function of fibrinolytics in the treatment of thrombotic disease?

    <p>Dissolving existing clots</p> Signup and view all the answers

    Which category of anticoagulants includes drugs like Warfarin and Dabigatran?

    <p>Oral anticoagulants</p> Signup and view all the answers

    What is the mechanism of action of ADP receptor inhibitors?

    <p>Prevent ADP binding to platelets</p> Signup and view all the answers

    Which type of inhibitors prevent platelets from binding to fibrinogen and forming a platelet plug?

    <p>Glycoprotein IIb/IIIa inhibitors</p> Signup and view all the answers

    What is the primary effect of phosphodiesterase inhibitors on platelets?

    <p>Increase cAMP levels</p> Signup and view all the answers

    Which type of inhibitors block the action of equilibrative nucleoside transporters?

    <p>Adenosine reuptake inhibitors</p> Signup and view all the answers

    Which receptors do protease-activated receptor-1 antagonists inhibit on platelets?

    <p>Protease-activated receptors</p> Signup and view all the answers

    Which antiplatelet/antithrombotic medication is recommended for individuals with evidence of coronary artery disease?

    <p>Clopidogrel</p> Signup and view all the answers

    Which of the following conditions is a contraindication for the use of Vorapaxar?

    <p>History of stroke</p> Signup and view all the answers

    What is the primary function of thrombolytic agents in the body?

    <p>Activate circulating plasminogen</p> Signup and view all the answers

    Which medication acts on fibrin-bound plasminogen within a thrombus and interferes with circulating plasminogen?

    <p>Alteplase</p> Signup and view all the answers

    In which condition would Alteplase be used as a medication?

    <p>Pulmonary embolism</p> Signup and view all the answers

    Which antiplatelet agent is approved for patients with unstable angina when PCI is planned within 24 hours?

    <p>Abciximab</p> Signup and view all the answers

    What is the main bleeding risk condition that prevents the use of Vorapaxar in patients?

    <p>History of stroke</p> Signup and view all the answers

    What is the main mechanism of action of warfarin?

    <p>Inhibiting the synthesis of Vitamin K</p> Signup and view all the answers

    How long does it typically take for the anticoagulant action of warfarin to start?

    <p>1-3 days</p> Signup and view all the answers

    What is the most common method for adjusting the dose of warfarin?

    <p>INR monitoring</p> Signup and view all the answers

    What is the main route of excretion for warfarin in the body?

    <p>Both urine and faeces</p> Signup and view all the answers

    Which laboratory test is a better indicator of the effect of oral anticoagulants like warfarin?

    <p>INR (international normalized ratio)</p> Signup and view all the answers

    What are some common adverse effects associated with warfarin therapy?

    <p>Alopecia, dermatitis, and diarrhoea</p> Signup and view all the answers

    Which adverse effect is commonly associated with thrombolytic agents?

    <p>Internal bleeding</p> Signup and view all the answers

    Which group of drugs specifically targets the clotting cascade enzymes?

    <p>Anticoagulants</p> Signup and view all the answers

    What is the mechanism of action of antiplatelet drugs?

    <p>Prevent platelets from clumping together</p> Signup and view all the answers

    When are fibrinolytics typically used in the treatment process?

    <p>After clot formation</p> Signup and view all the answers

    Which drug is a specific antidote for fibrinolytic agents and has adjunctive value in other conditions?

    <p>Epsilon amino-caproic acid (EACA)</p> Signup and view all the answers

    What laboratory test is commonly used to monitor the effectiveness of Warfarin?

    <p>International normalized ratio (INR)</p> Signup and view all the answers

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