Platelet Inhibitors Quiz

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Questions and Answers

Which type of drugs prevent blood clotting by suppressing the synthesis or function of clotting factors?

  • Anticoagulants (correct)
  • Fibrinolytics
  • Antiplatelet drugs
  • Calcium complexing agents

Which substance is used for anticoagulation in vitro to prevent blood clotting during investigations?

  • Fondaparinux
  • Argatroban
  • Heparin
  • Sodium citrate (correct)

Which type of thrombosis is often associated with myocardial infarction, stroke, and ischemia?

  • White thrombosis
  • Venous thrombosis
  • Arterial thrombosis (correct)
  • Thromboembolism

What can venous emboli potentially block in the body's circulation?

<p>Arterioles in the lung (B)</p> Signup and view all the answers

What is the primary function of fibrinolytics in the treatment of thrombotic disease?

<p>Dissolving existing clots (C)</p> Signup and view all the answers

Which category of anticoagulants includes drugs like Warfarin and Dabigatran?

<p>Oral anticoagulants (B)</p> Signup and view all the answers

What is the mechanism of action of ADP receptor inhibitors?

<p>Prevent ADP binding to platelets (A)</p> Signup and view all the answers

Which type of inhibitors prevent platelets from binding to fibrinogen and forming a platelet plug?

<p>Glycoprotein IIb/IIIa inhibitors (D)</p> Signup and view all the answers

What is the primary effect of phosphodiesterase inhibitors on platelets?

<p>Increase cAMP levels (B)</p> Signup and view all the answers

Which type of inhibitors block the action of equilibrative nucleoside transporters?

<p>Adenosine reuptake inhibitors (C)</p> Signup and view all the answers

Which receptors do protease-activated receptor-1 antagonists inhibit on platelets?

<p>Protease-activated receptors (A)</p> Signup and view all the answers

Which antiplatelet/antithrombotic medication is recommended for individuals with evidence of coronary artery disease?

<p>Clopidogrel (C)</p> Signup and view all the answers

Which of the following conditions is a contraindication for the use of Vorapaxar?

<p>History of stroke (C)</p> Signup and view all the answers

What is the primary function of thrombolytic agents in the body?

<p>Activate circulating plasminogen (D)</p> Signup and view all the answers

Which medication acts on fibrin-bound plasminogen within a thrombus and interferes with circulating plasminogen?

<p>Alteplase (A)</p> Signup and view all the answers

In which condition would Alteplase be used as a medication?

<p>Pulmonary embolism (A)</p> Signup and view all the answers

Which antiplatelet agent is approved for patients with unstable angina when PCI is planned within 24 hours?

<p>Abciximab (A)</p> Signup and view all the answers

What is the main bleeding risk condition that prevents the use of Vorapaxar in patients?

<p>History of stroke (D)</p> Signup and view all the answers

What is the main mechanism of action of warfarin?

<p>Inhibiting the synthesis of Vitamin K (D)</p> Signup and view all the answers

How long does it typically take for the anticoagulant action of warfarin to start?

<p>1-3 days (C)</p> Signup and view all the answers

What is the most common method for adjusting the dose of warfarin?

<p>INR monitoring (C)</p> Signup and view all the answers

What is the main route of excretion for warfarin in the body?

<p>Both urine and faeces (C)</p> Signup and view all the answers

Which laboratory test is a better indicator of the effect of oral anticoagulants like warfarin?

<p>INR (international normalized ratio) (D)</p> Signup and view all the answers

What are some common adverse effects associated with warfarin therapy?

<p>Alopecia, dermatitis, and diarrhoea (C)</p> Signup and view all the answers

Which adverse effect is commonly associated with thrombolytic agents?

<p>Internal bleeding (C)</p> Signup and view all the answers

Which group of drugs specifically targets the clotting cascade enzymes?

<p>Anticoagulants (C)</p> Signup and view all the answers

What is the mechanism of action of antiplatelet drugs?

<p>Prevent platelets from clumping together (B)</p> Signup and view all the answers

When are fibrinolytics typically used in the treatment process?

<p>After clot formation (D)</p> Signup and view all the answers

Which drug is a specific antidote for fibrinolytic agents and has adjunctive value in other conditions?

<p>Epsilon amino-caproic acid (EACA) (D)</p> Signup and view all the answers

What laboratory test is commonly used to monitor the effectiveness of Warfarin?

<p>International normalized ratio (INR) (B)</p> Signup and view all the answers

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