30 Questions
Which type of drugs prevent blood clotting by suppressing the synthesis or function of clotting factors?
Anticoagulants
Which substance is used for anticoagulation in vitro to prevent blood clotting during investigations?
Sodium citrate
Which type of thrombosis is often associated with myocardial infarction, stroke, and ischemia?
Arterial thrombosis
What can venous emboli potentially block in the body's circulation?
Arterioles in the lung
What is the primary function of fibrinolytics in the treatment of thrombotic disease?
Dissolving existing clots
Which category of anticoagulants includes drugs like Warfarin and Dabigatran?
Oral anticoagulants
What is the mechanism of action of ADP receptor inhibitors?
Prevent ADP binding to platelets
Which type of inhibitors prevent platelets from binding to fibrinogen and forming a platelet plug?
Glycoprotein IIb/IIIa inhibitors
What is the primary effect of phosphodiesterase inhibitors on platelets?
Increase cAMP levels
Which type of inhibitors block the action of equilibrative nucleoside transporters?
Adenosine reuptake inhibitors
Which receptors do protease-activated receptor-1 antagonists inhibit on platelets?
Protease-activated receptors
Which antiplatelet/antithrombotic medication is recommended for individuals with evidence of coronary artery disease?
Clopidogrel
Which of the following conditions is a contraindication for the use of Vorapaxar?
History of stroke
What is the primary function of thrombolytic agents in the body?
Activate circulating plasminogen
Which medication acts on fibrin-bound plasminogen within a thrombus and interferes with circulating plasminogen?
Alteplase
In which condition would Alteplase be used as a medication?
Pulmonary embolism
Which antiplatelet agent is approved for patients with unstable angina when PCI is planned within 24 hours?
Abciximab
What is the main bleeding risk condition that prevents the use of Vorapaxar in patients?
History of stroke
What is the main mechanism of action of warfarin?
Inhibiting the synthesis of Vitamin K
How long does it typically take for the anticoagulant action of warfarin to start?
1-3 days
What is the most common method for adjusting the dose of warfarin?
INR monitoring
What is the main route of excretion for warfarin in the body?
Both urine and faeces
Which laboratory test is a better indicator of the effect of oral anticoagulants like warfarin?
INR (international normalized ratio)
What are some common adverse effects associated with warfarin therapy?
Alopecia, dermatitis, and diarrhoea
Which adverse effect is commonly associated with thrombolytic agents?
Internal bleeding
Which group of drugs specifically targets the clotting cascade enzymes?
Anticoagulants
What is the mechanism of action of antiplatelet drugs?
Prevent platelets from clumping together
When are fibrinolytics typically used in the treatment process?
After clot formation
Which drug is a specific antidote for fibrinolytic agents and has adjunctive value in other conditions?
Epsilon amino-caproic acid (EACA)
What laboratory test is commonly used to monitor the effectiveness of Warfarin?
International normalized ratio (INR)
Test your knowledge on ADP receptor inhibitors, phosphodiesterase inhibitors, and glycoprotein IIb/IIIa inhibitors which are used to prevent platelet activation and aggregation.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
