Podcast
Questions and Answers
The second type of mutation associated with cancer is referred to as ___ and is inherited.
The second type of mutation associated with cancer is referred to as ___ and is inherited.
False
Tamoxifen is associated with an increased risk of venous thromboembolism (VTE) and endometrial cancer.
Tamoxifen is associated with an increased risk of venous thromboembolism (VTE) and endometrial cancer.
True
BRCA1 and BRCA2 are considered oncogenes that are recessive.
BRCA1 and BRCA2 are considered oncogenes that are recessive.
False
The management for patients with TP53 mutations includes genetic counselling and annual mammography.
The management for patients with TP53 mutations includes genetic counselling and annual mammography.
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The SPIKES model emphasizes the importance of empathy only after sharing the diagnosis.
The SPIKES model emphasizes the importance of empathy only after sharing the diagnosis.
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Inherited cancer is confirmed through clinical symptoms alone.
Inherited cancer is confirmed through clinical symptoms alone.
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Early age at diagnosis is a feature suggestive of hereditary cancer.
Early age at diagnosis is a feature suggestive of hereditary cancer.
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Prophylactic treatment for breast cancer includes the use of antibiotics.
Prophylactic treatment for breast cancer includes the use of antibiotics.
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HNPCC can be suspected in patients with at least 2 affected relatives from 1 successive generation.
HNPCC can be suspected in patients with at least 2 affected relatives from 1 successive generation.
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FAP prophylactic surgery depends on polyp size, but not on number or dysplasia.
FAP prophylactic surgery depends on polyp size, but not on number or dysplasia.
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Peutz-Jeghers syndrome is caused by germline mutations in the STK11 gene.
Peutz-Jeghers syndrome is caused by germline mutations in the STK11 gene.
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A patient with persistent dyspepsia over the age of 55 should receive a non-urgent endoscopy.
A patient with persistent dyspepsia over the age of 55 should receive a non-urgent endoscopy.
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Urgent CT of the pancreas is indicated for patients over 50 with weight loss and abdominal pain.
Urgent CT of the pancreas is indicated for patients over 50 with weight loss and abdominal pain.
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A positive faecal occult blood test in a patient over 40 years is a clinical feature prompting urgent referral for lower GI cancer.
A positive faecal occult blood test in a patient over 40 years is a clinical feature prompting urgent referral for lower GI cancer.
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Clubbing is listed as a clinical feature for urgent CXR in patients over 50 years.
Clubbing is listed as a clinical feature for urgent CXR in patients over 50 years.
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Chemotherapy is the only treatment that utilizes a systemic approach.
Chemotherapy is the only treatment that utilizes a systemic approach.
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Adjuvant chemotherapy is administered before surgical procedures to reduce tumor size.
Adjuvant chemotherapy is administered before surgical procedures to reduce tumor size.
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Alkylating agents operate by interrupting the unwinding of DNA.
Alkylating agents operate by interrupting the unwinding of DNA.
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Combination chemotherapy is less effective than single-agent chemotherapy due to increased toxicity risks.
Combination chemotherapy is less effective than single-agent chemotherapy due to increased toxicity risks.
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Monoclonal antibodies enhance host immunity by specifically targeting antigens on tumors.
Monoclonal antibodies enhance host immunity by specifically targeting antigens on tumors.
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Palliative chemotherapy aims solely to cure cancer.
Palliative chemotherapy aims solely to cure cancer.
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Vinca alkaloids and taxanes are classified as antimetabolites.
Vinca alkaloids and taxanes are classified as antimetabolites.
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Interference with cell metabolism during DNA and protein synthesis is the primary mechanism of antimetabolites.
Interference with cell metabolism during DNA and protein synthesis is the primary mechanism of antimetabolites.
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The TNM staging system includes components for measurement of primary tumour, lymph node involvement, and distance of metastasis.
The TNM staging system includes components for measurement of primary tumour, lymph node involvement, and distance of metastasis.
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Monoclonal antibodies are used to enhance the effects of radiation therapy exclusively.
Monoclonal antibodies are used to enhance the effects of radiation therapy exclusively.
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An urgent MRI is warranted for patients presenting with sudden loss of limb function.
An urgent MRI is warranted for patients presenting with sudden loss of limb function.
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The Duke’s classification is a staging system specifically used for breast cancer.
The Duke’s classification is a staging system specifically used for breast cancer.
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The use of cytotoxic drugs in cancer treatment is defined as chemotherapy.
The use of cytotoxic drugs in cancer treatment is defined as chemotherapy.
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Weight loss, anorexia, and DVT are classified as specific signs of cancer.
Weight loss, anorexia, and DVT are classified as specific signs of cancer.
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The radioactive tracer FDG used in PET-CT scans highlights areas of decreased metabolism.
The radioactive tracer FDG used in PET-CT scans highlights areas of decreased metabolism.
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A common outcome of the TNM staging system is to classify cancers into a simpler overall disease stage ranging from 0 to IV.
A common outcome of the TNM staging system is to classify cancers into a simpler overall disease stage ranging from 0 to IV.
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Alopecia can be managed with a cold cap and a wig.
Alopecia can be managed with a cold cap and a wig.
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Extravasation of chemotherapy presents only with redness and no pain.
Extravasation of chemotherapy presents only with redness and no pain.
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Dry warm compresses are used for DNA-binding drugs to increase drug distribution.
Dry warm compresses are used for DNA-binding drugs to increase drug distribution.
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Clinical trials may result in less effective treatment as a disadvantage.
Clinical trials may result in less effective treatment as a disadvantage.
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Beau’s lines signify uninterrupted nail keratin synthesis due to medication.
Beau’s lines signify uninterrupted nail keratin synthesis due to medication.
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Premature ovarian failure can lead to sterility as a side effect of chemotherapy and radiotherapy.
Premature ovarian failure can lead to sterility as a side effect of chemotherapy and radiotherapy.
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Semen cryopreservation is a fertility preservation technique recommended for women prior to chemotherapy.
Semen cryopreservation is a fertility preservation technique recommended for women prior to chemotherapy.
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Palliative radiotherapy aims to provide curative treatment for cancer cases.
Palliative radiotherapy aims to provide curative treatment for cancer cases.
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Each Beau's line corresponds to a cycle of chemotherapy.
Each Beau's line corresponds to a cycle of chemotherapy.
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Erythema and moist desquamation are common skin reactions associated with radiotherapy.
Erythema and moist desquamation are common skin reactions associated with radiotherapy.
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The early reactions of radiotherapy typically manifest two weeks after treatment begins.
The early reactions of radiotherapy typically manifest two weeks after treatment begins.
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The management of mucositis during radiotherapy includes dental check-ups prior to therapy.
The management of mucositis during radiotherapy includes dental check-ups prior to therapy.
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Hydration and high-fiber diets are recommended for managing diarrhea caused by radiotherapy.
Hydration and high-fiber diets are recommended for managing diarrhea caused by radiotherapy.
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Secondary cancers are classified as late reactions of radiotherapy.
Secondary cancers are classified as late reactions of radiotherapy.
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Bronchodilators and steroids are utilized to manage dry cough associated with pneumonitis in radiotherapy.
Bronchodilators and steroids are utilized to manage dry cough associated with pneumonitis in radiotherapy.
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Patients undergoing radiotherapy are advised to rest extensively to combat tiredness.
Patients undergoing radiotherapy are advised to rest extensively to combat tiredness.
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Description
Test your knowledge on inherited cancer types, genetic mutations, and their management. This quiz covers key concepts such as BRCA genes, the SPIKES model, and hereditary cancer syndromes. Understand the implications of genetic counseling and the clinical features associated with various cancers.
