7 Questions
What is the role of haemagglutinin in the influenza virus?
To interact with the host-cell surface receptor, containing silica acid
What is the function of neuraminidase in the influenza virus?
To cleave off the terminal silica acid, allowing the virus to leave the cell
What is the effect of inhibiting neuraminidase on the influenza virus?
It prevents the release of the virus from the cell, thus inhibiting virus multiplication
What is the aim of developing neuraminidase inhibitors as a class of drugs?
To control the virus by inhibiting neuraminidase, thus preventing the release of the virus from the cell
What is the role of silica acid in the influenza virus?
It is a component of the host-cell surface receptor, containing silica acid
What is the result of the interaction between the influenza virus and the host-cell surface receptor, containing silica acid?
The virus is able to bind to the target cell, allowing it to replicate
What is the function of neuraminidase in relation to sialic acid?
It breaks the bond between the sugar and the glycoprotein to give sialic acid
Learn about the mechanism of influenza virus replication, specifically the role of neuraminidase in cleaving silica acid, allowing the virus to leave the host cell and infect others. Understand how inhibiting neuraminidase can prevent the spread of the virus.
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