Podcast
Questions and Answers
Which enzyme is required for the replication of plus sense ssRNA viruses?
Which enzyme is required for the replication of plus sense ssRNA viruses?
What is a primary characteristic of the lysogenic replication cycle?
What is a primary characteristic of the lysogenic replication cycle?
How does the lytic cycle of viral replication primarily differ from the lysogenic cycle?
How does the lytic cycle of viral replication primarily differ from the lysogenic cycle?
What is the 'end problem' in linear genomes during viral replication?
What is the 'end problem' in linear genomes during viral replication?
Signup and view all the answers
What is a concatemers' role in viral replication?
What is a concatemers' role in viral replication?
Signup and view all the answers
What type of viruses are capable of undergoing lysogeny?
What type of viruses are capable of undergoing lysogeny?
Signup and view all the answers
Which scenario triggers the lytic cycle in a temperate phage?
Which scenario triggers the lytic cycle in a temperate phage?
Signup and view all the answers
What is a prophage in the context of viral replication?
What is a prophage in the context of viral replication?
Signup and view all the answers
What type of genome does HIV contain?
What type of genome does HIV contain?
Signup and view all the answers
What is the primary function of reverse transcriptase in the retrovirus replication cycle?
What is the primary function of reverse transcriptase in the retrovirus replication cycle?
Signup and view all the answers
Retroviruses primarily replicate through which of the following types of viral enzymes?
Retroviruses primarily replicate through which of the following types of viral enzymes?
Signup and view all the answers
What mechanism allows retroviruses to solve the end problem during replication?
What mechanism allows retroviruses to solve the end problem during replication?
Signup and view all the answers
What primarily contributes to the high mutation rate of RNA viruses?
What primarily contributes to the high mutation rate of RNA viruses?
Signup and view all the answers
Why are DNA viruses less common in animals compared to bacteria?
Why are DNA viruses less common in animals compared to bacteria?
Signup and view all the answers
What function does the integrase provide during the retroviral replication cycle?
What function does the integrase provide during the retroviral replication cycle?
Signup and view all the answers
Which activity does not belong to the reverse transcriptase enzyme?
Which activity does not belong to the reverse transcriptase enzyme?
Signup and view all the answers
What role does the lambda repressor (cI) play in the lysogenic replication cycle?
What role does the lambda repressor (cI) play in the lysogenic replication cycle?
Signup and view all the answers
Which element is responsible for triggering the lytic pathway?
Which element is responsible for triggering the lytic pathway?
Signup and view all the answers
What is the initial condition that favors the stability of the CII protein during infection?
What is the initial condition that favors the stability of the CII protein during infection?
Signup and view all the answers
What is the primary function of the lambda integrase during lysogeny?
What is the primary function of the lambda integrase during lysogeny?
Signup and view all the answers
What outcome results from a non-sense mutation in the cro repressor?
What outcome results from a non-sense mutation in the cro repressor?
Signup and view all the answers
Which of the following best describes rolling circle replication?
Which of the following best describes rolling circle replication?
Signup and view all the answers
In the context of lambda phage, what does the activity of RecA imply?
In the context of lambda phage, what does the activity of RecA imply?
Signup and view all the answers
Which combination of mutations would potentially trap a lambda prophage within a bacterial genome?
Which combination of mutations would potentially trap a lambda prophage within a bacterial genome?
Signup and view all the answers
Study Notes
Viral Replication
- Viral replication involves various processes depending on the viral type (DNA or RNA).
- Different classes of viruses have distinct replication strategies.
- DNA viruses (Class I & VII) typically replicate through semi-conservative replication.
- RNA viruses (Classes II-VI) employ diverse replication mechanisms.
- Retroviruses (Class VI) use reverse transcriptase to convert RNA into DNA.
- Some viruses integrate their genetic material into the host's genome (e.g., retroviruses and temperate phages).
Problems in Viral Replication
- Linear genomes pose challenges during replication.
- Circular permutation for T4 phage solves the end problem of replicating linear genomes.
- Terminal redundancy in certain phages (e.g., T4) aids in replication.
- Formation of concatemers by joining ends creates long DNA molecules for multiple viral genomes.
- Certain viruses (e.g., HIV) employ terminal repeats to copy their ends during replication.
- Some viruses use terminal proteins or other molecules as primers for replication.
- Host DNA replication processes are impacted during viral replication.
Temparate Phage and Lysogeny
- Temperate phages can undergo both lytic and lysogenic cycles.
- Lysogeny involves viral DNA integrating into the host genome.
- Lysogenic viral DNA (prophage) replicates along with the host DNA, producing multiple prophage copies.
- The lysogenic pathway is often induced during adverse conditions, triggering the lytic cycle.
Retrovirus Replication
- Retroviruses use reverse transcriptase to convert their RNA genome into DNA.
- The integrated DNA is then transcribed and translated to form new viral components.
- Retroviruses employ terminal repeats to address the end-problem.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Related Documents
Description
Test your understanding of the viral replication processes and the challenges faced during each type of viral genome replication. Explore the mechanisms used by DNA and RNA viruses, including retroviruses and their unique strategies. This quiz will help reinforce your knowledge of viral biology.
