Inflammatory Response Mediators Quiz
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Questions and Answers

What are the three steps involved in phagocytosis?

  • Recognition, engulfment, exocytosis
  • Ingestion, transportation, elimination
  • Identification, ingestion, destruction
  • Recognition and attachment, engulfment, killing or degradation (correct)

    • Which type of cells are involved in phagocytosis?

  • Neutrophils, Macrophages (correct)
  • T cells
  • Eosinophils, Basophils
  • B cells

    • What is the main cellular infiltrate in Acute Inflammation?

  • Eosinophils
  • Monocytes
  • Neutrophils (correct)
  • Lymphocytes

    • What is the predominant cell type in Chronic Inflammation?

    <p>Monocytes/Macrophages &amp; lymphocytes (B)</p> Signup and view all the answers

    How would you classify inflammation based on its duration?

    <p>Acute and chronic (B)</p> Signup and view all the answers

    Which type of immunity is associated with Acute Inflammation?

    <p>Innate immunity (C)</p> Signup and view all the answers

    What is the usual outcome of Chronic Inflammation?

    <p>Tissue destruction, fibrosis, necrosis (D)</p> Signup and view all the answers

    Which type of inflammatory reaction shows a rapid onset?

    <p>Acute Inflammation (B)</p> Signup and view all the answers

    What is the duration of Chronic Inflammation compared to Acute Inflammation?

    <p>Weeks/months/years (B)</p> Signup and view all the answers

    Which component of acute inflammation involves the alteration in permeability of microvasculature?

    <p>Microvascular Changes (C)</p> Signup and view all the answers

    Inflammatory mediators are classified into which two main categories based on their origin?

    <p>Cell-derived and Plasma-derived mediators (A)</p> Signup and view all the answers

    What do active inflammatory mediators help in response to various injurious stimuli?

    <p>Trigger inflammation (D)</p> Signup and view all the answers

    Which effect can inflammatory mediators have on blood vessels?

    <p>Vasodilation (D)</p> Signup and view all the answers

    What is the main purpose of inflammatory mediators binding to specific receptors?

    <p>Stimulate release of other mediators (D)</p> Signup and view all the answers

    Which cellular process involves emigration, accumulation, and activation of white blood cells at the site of injury?

    <p>Cellular Events (B)</p> Signup and view all the answers

    What triggers the production and release of active inflammatory mediators?

    <p>Damaged tissues and microbes (C)</p> Signup and view all the answers

    What is the main effect of vasoactive amines like histamine during inflammation?

    <p>Vasodilatation (B)</p> Signup and view all the answers

    Which cell types are the sources of histamine in the context of inflammation?

    <p>Mast cells, basophils, and platelets (A)</p> Signup and view all the answers

    What is the role of arachidonic acid derivatives like prostaglandins in inflammation?

    <p>Mediate vasodilation, pain, fever (A)</p> Signup and view all the answers

    What is the main function of cytokines?

    <p>Modulate the functions of other cell types (D)</p> Signup and view all the answers

    Which of the following is a role of leukotrienes in inflammation?

    <p>Mediate increased vascular permeability (B)</p> Signup and view all the answers

    What is a notable effect of platelet-activating factors (PAF) in inflammation?

    <p>Vasodilation (D)</p> Signup and view all the answers

    Which type of cytokines are produced by monocytes/macrophages?

    <p>Monokines (B)</p> Signup and view all the answers

    What is the role of Interferons (INF) among cytokines?

    <p>Inhibit virus replication and activate macrophages (A)</p> Signup and view all the answers

    Which cell types primarily produce Platelet-Activating Factor (PAF) during inflammation?

    <p>Mast cells and neutrophils (B)</p> Signup and view all the answers

    Which cytokine is involved in killing tumor cells but can also lead to weight loss?

    <p>Tumor necrosis factors (B)</p> Signup and view all the answers

    What is the source of the vasoactive amine histamine during an inflammatory response?

    <p>Granules of platelets and leukocytes (D)</p> Signup and view all the answers

    What is the function of Nitric Oxide (NO) in inflammation?

    <p>Act as a vasodilator (D)</p> Signup and view all the answers

    What is the function of nitric oxide (NO) in the context of inflammation?

    <p>Inducing smooth muscle relaxation (D)</p> Signup and view all the answers

    What must be done to plasma protein-derived mediators before they become active in inflammation?

    <p>Transform them into an active form with an activator (D)</p> Signup and view all the answers

    How do Arachidonic Acid (AA) derivatives contribute to inflammation?

    <p>Mediate various stages of inflammation (B)</p> Signup and view all the answers

    Which type of cytokines act between leukocytes?

    <p>Interleukins (IL) (D)</p> Signup and view all the answers

    What are the Cell-Derived Mediators of Inflammation?

    <p>Cytokines (C)</p> Signup and view all the answers

    Which type of cell produces nitric oxide (NO) in inflammation?

    <p>Macrophages (A)</p> Signup and view all the answers

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