Podcast
Questions and Answers
What is the most likely diagnosis for Luke based on the presented case?
What is the most likely diagnosis for Luke based on the presented case?
- Inclusion body myositis (correct)
- Dermatomyositis
- Lambert-Eaton myasthenic syndrome
- Polymyositis
Which of the following diagnostic tests would be most beneficial for confirming the suspected diagnosis?
Which of the following diagnostic tests would be most beneficial for confirming the suspected diagnosis?
- Muscle biopsy (correct)
- Autoantibody testing
- Serum creatine kinase (CK) levels
- Electromyography (EMG)
What histological findings would be expected in muscle biopsy of a patient with suspected inclusion body myositis?
What histological findings would be expected in muscle biopsy of a patient with suspected inclusion body myositis?
- Endomysial inflammation with CD8+ T cells
- Rimmed vacuoles and cytoplasmic inclusions (correct)
- Prominent perimysial inflammation
- Presence of perifascicular atrophy
Which of the following is a characteristic feature of dermatomyositis that is not present in Luke's case?
Which of the following is a characteristic feature of dermatomyositis that is not present in Luke's case?
What autoimmune marker may be elevated in patients with inflammatory myopathies such as dermatomyositis and polymyositis?
What autoimmune marker may be elevated in patients with inflammatory myopathies such as dermatomyositis and polymyositis?
Which of the following is not typically associated with Lambert-Eaton myasthenic syndrome, making it less likely in Luke's case?
Which of the following is not typically associated with Lambert-Eaton myasthenic syndrome, making it less likely in Luke's case?
Which autoimmune systemic connective tissue disease primarily affects the skeletal muscles and is characterized by a prominent mononuclear inflammatory cell infiltrate in the endomysium?
Which autoimmune systemic connective tissue disease primarily affects the skeletal muscles and is characterized by a prominent mononuclear inflammatory cell infiltrate in the endomysium?
What is the serum total creatine kinase level in the patient described?
What is the serum total creatine kinase level in the patient described?
Which muscle group exhibited asymmetric atrophy and had a muscle strength of 1/5 on hip flexion and knee extension of the right side?
Which muscle group exhibited asymmetric atrophy and had a muscle strength of 1/5 on hip flexion and knee extension of the right side?
What was the result of serology testing for cytoplasmic 5’-nucleotidase 1A (cN1A) autoantibody?
What was the result of serology testing for cytoplasmic 5’-nucleotidase 1A (cN1A) autoantibody?
Which of the following is NOT mentioned as a common environmental agent implicated in idiopathic inflammatory myopathies?
Which of the following is NOT mentioned as a common environmental agent implicated in idiopathic inflammatory myopathies?
What does IIM stand for in the text?
What does IIM stand for in the text?
What is the normal range for serum total creatine kinase level?
What is the normal range for serum total creatine kinase level?
Which of the following are the components of basic metabolic panel mentioned in the text?
Which of the following are the components of basic metabolic panel mentioned in the text?
What does ESR stand for in the text?
What does ESR stand for in the text?
What was the main pathological finding in the muscle biopsy of right vastus lateralis?
What was the main pathological finding in the muscle biopsy of right vastus lateralis?
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