34 Questions
When is the peak time for detecting a respiratory virus?
During the onset of clinical signs
How long do IgG antibodies last in the body?
Several months
How long do IgM antibodies last in the body?
A few months
Why is it important to follow up a sample 2 weeks later with a convalescent sample if the patient is vaccinated or previously exposed to a specific disease?
To measure the rapid increase in antibody levels
What type of blood sample is recommended for antibody testing?
Coagulated blood
Which type of sample is commonly a first line diagnostic used to detect respiratory viruses?
Nasopharyngeal swab
In addition to the individual showing clinical signs, why is it valuable to sample other animals in a group?
To detect the presence of the virus
Which immune response takes longer to develop in a naïve individual?
Adaptive immune response
Which type of sample is considered less invasive for respiratory disease testing?
Saliva sample
Which inflammatory markers are commonly tested in animals?
Fibrinogen, C reactive protein, and Amyloid A
What does an elevated C reactive protein (CRP) indicate in dogs?
Inflammatory disorder
Which acute phase protein is primarily used as an inflammatory marker in horses and cats?
Serum Amyloid A (SAA)
What is the role of fibrinogen in detecting infection?
It helps in blood clotting during infection
Which acute phase protein is primarily used as an inflammatory marker in cows?
Haptoglobin
Which acute phase protein is primarily used as an inflammatory marker in dogs?
CRP
What is the purpose of effective sampling?
All of the above
What is the definition of effective sampling?
All of the above
What do acute phase proteins increase in response to?
Both infection and inflammation
Which inflammatory markers are commonly used in combination to detect infection in horses?
Fibrinogen and SAA
What are the three inflammatory markers?
Fibrinogen, C reactive protein, Amyloid A
Which acute phase protein is primarily used as an inflammatory marker in pigs?
MAP protein
What is the primary acute phase protein used in dogs?
C reactive protein (CRP)
Which acute phase protein is primarily used as an inflammatory marker in cows?
Amyloid A and haptoglobin
What is the purpose of effective sampling?
To ensure the right type of sample is taken correctly from the right place and animals at the right time
What do acute phase proteins increase in response to?
Infection or inflammation
What is the role of fibrinogen in detecting infection?
Fibrinogen is an acute phase protein that is produced in response to cytokines present during infection
What is the recommended timing for taking a respiratory sample in the infection process?
Peak time for detecting the virus is around 3 or 4 days into the onset of clinical signs, but this varies depending on the pathogen.
How long do IgG antibodies typically last in the body?
IgG antibodies can last for months and months.
What is the purpose of taking a convalescent sample?
To pick up the anamnestic response to the infection, where there is a rapid and high increase in antibody levels.
What type of blood sample is recommended for PCR testing?
Coagulated blood is recommended for PCR testing.
Which type of sample is considered less invasive for respiratory disease testing?
Milk and saliva samples are considered less invasive for respiratory disease testing.
Why is it valuable to sample other animals in a group?
The virus may be present but not shown clinically in other animals in the group.
How long do IgM antibodies typically last in the body?
IgM antibodies last for around 3 months.
What is the potential interference caused by Li hep tube in PCR testing?
Li hep tube can cause interference in PCR testing.
Test your knowledge on effective sampling of inflammatory markers such as Fibrinogen, C-reactive protein (CRP), and Amyloid A. Learn about the different factors that can cause elevated CRP in dogs, including bacterial, parasitic, and viral infections. Explore specific pathogens like Bordatella bronchiseptica, Leishmaniasis, Parvovirus, Escherichia coli, Babesis canis, Erlichia canis, Leptospira interrogans
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