Inflammatory Bowel Disease Treatment Goals
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Questions and Answers

What is one of the main goals of pharmacologic therapy for inflammatory bowel disease (IBD)?

  • To improve the taste of food
  • To reduce the incidence of relapse (correct)
  • To cure the disease completely
  • To enhance digestive efficiency
  • Corticosteroids are used to treat chronic intestinal inflammation only during acute attacks.

    False

    What type of drugs may be prescribed to slow GI motility in IBD patients?

    Antidiarrheal agents

    Drugs used to treat IBD include _______ acid derivatives, corticosteroids, biologic therapies, and Janus-associated kinase inhibitors.

    <p>5-aminosalicylic</p> Signup and view all the answers

    What route of administration is NOT used to deliver drug therapy for IBD?

    <p>Inhalation</p> Signup and view all the answers

    Match the drug categories with their purposes:

    <p>5-aminosalicylic acid derivatives = Reduce inflammation Corticosteroids = Induce remission during acute exacerbations Antibiotics = Address intestinal abscesses Antidiarrheal agents = Slow GI motility</p> Signup and view all the answers

    Patients with IBD should stop drug therapy immediately once they become asymptomatic.

    <p>False</p> Signup and view all the answers

    What should patients undergoing immunosuppressive treatment for IBD avoid?

    <p>Exposure to infectious diseases</p> Signup and view all the answers

    What is one potential benefit of an elemental diet like Ensure for patients with Crohn disease?

    <p>It contains all essential nutrients.</p> Signup and view all the answers

    Increased dietary fiber is beneficial for all patients with Crohn disease.

    <p>False</p> Signup and view all the answers

    What is the role of a nutritionist in the management of patients with Crohn disease?

    <p>To ensure micronutrient needs are met and to prevent undernourishment.</p> Signup and view all the answers

    Patients with IBD often seek _____ therapies due to the chronic nature of their condition.

    <p>integrative</p> Signup and view all the answers

    Match the following self-care measures with their benefits:

    <p>30-minute walk = Improves physical health Abdominal massage = Relieves discomfort Warm bath = Relaxes rectal muscles Mindfulness training = Improves mental well-being</p> Signup and view all the answers

    During an acute exacerbation of Crohn disease, what is one method of nutritional support?

    <p>Total parenteral nutrition (TPN)</p> Signup and view all the answers

    Probiotics have conclusively demonstrated benefits for all patients with IBS.

    <p>False</p> Signup and view all the answers

    What are some common issues faced by patients with IBD that may affect their quality of life?

    <p>Increased stress levels, depression, and fatigue.</p> Signup and view all the answers

    Study Notes

    Inflammatory Bowel Disease Treatment Goals

    • Treat acute inflammation as quickly as possible
    • Reduce the likelihood of relapses
    • Manage chronic intestinal inflammation

    Drug Therapy Administration Routes for IBD

    • Oral: Systemic action
    • Subcutaneous: Systemic action
    • Intravenous: Systemic action
    • Oral Time-release: Local action in ileum and upper colon
    • Rectal: Local action to reduce inflammation

    Drug Categories for IBD

    • 5-Aminosalicylic Acid Derivatives: Not discussed in detail
    • Corticosteroids: Used for acute exacerbations to reduce inflammation and induce remission
    • Biologic Therapies: Three categories (not specified)
    • Janus-associated Kinase (JAK) Inhibitors: Not discussed in detail

    Corticosteroid Therapy

    • Often used for acute exacerbations
    • Can be challenging to withdraw from without experiencing relapse
    • Long-term low-dose therapy may be necessary

    Antibiotic or Antiprotozoal Therapy

    • Used in cases of intestinal abscesses or fistulas
    • May be part of treatment due to link between IBD and pathogenic bacteria

    Antidiarrheal Agents

    • Used for chronic diarrhea associated with IBD
    • Examples include loperamide (Imodium) and diphenoxylate (Lomotil)
    • Safe for mild, chronic manifestations but not during acute attacks

    Drug Therapy Considerations

    • Continue medication even when asymptomatic
    • Immunosuppressant medications increase risk of exposure to infectious diseases
    • Report any disease symptoms or fevers to healthcare providers
    • Inform healthcare providers about IBD treatment when receiving treatment for other medical conditions
    • May need to adjust immunization schedules for pediatric patients on immunosuppressants

    Dietary Management

    • Individualized approach due to potential immune response stimulation
    • Some patients benefit from eliminating milk and milk products
    • Increased fiber can help reduce diarrhea and rectal symptoms, but contraindicated in intestinal strictures
    • Collaboration with a nutritionist is recommended to ensure adequate micronutrient intake, calories, and protein

    Bowel Rest During Exacerbation

    • Withholding food can promote bowel rest during acute Crohn disease exacerbations
    • Nutritional support through enteral or total parenteral nutrition (TPN)
    • TPN associated with higher complication risk compared to enteral nutrition
    • Elemental diets like Ensure can be prescribed to provide essential nutrients
    • Elemental diets may not always be palatable

    Complementary Health Approaches

    • Probiotics: Some preliminary evidence suggests potential benefit for IBS, but not conclusive and not all probiotics have the same effects
    • Alternative therapies: Lack of research limits conventional practitioner use, especially herbal supplements
    • Interactions with prescribed medications are possible, so patients should discuss all potential therapies with healthcare providers

    Quality of Life Improvement

    • May be impacted by stress levels, depression, and fatigue
    • Mindfulness training, cognitive-behavioral therapy, and stress management can help
    • Self-care measures like exercise, abdominal massage, and warm baths can manage discomfort

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    Description

    This quiz covers the treatment goals and drug therapy options for Inflammatory Bowel Disease (IBD). It addresses the management of acute inflammation, chronic intestinal inflammation, and various drug administration routes. Additionally, it discusses specific drug categories used to treat IBD, including corticosteroids and biologic therapies.

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