28 Questions
What is the main reason for redness in inflammation?
Vasodilatation
What causes pain in inflammation?
Compression of nerves by exudate
Which process involves leukocytes passing through gaps between intact endothelium?
Transmigration
What is the main reason for swelling of endothelial cells during inflammation?
Diapedesis through intact vessels
Which molecules cause the immobilization of leukocytes during adhesion in inflammation?
Integrin and Endothelial cells
What initiates the rolling phase of leukocytes during the inflammatory response?
Recognition of pathogens by leukocytes
What is the purpose of inflammation?
To eliminate the cause of injury
Which component is NOT involved in inflammation?
Nervous system
What is the main function of leukocytes in inflammation?
To eliminate pathogens and damaged cells
Which term describes the reaction of living tissue against injury?
Inflammation
What is the primary reason for leukocytes extravasation during inflammation?
To migrate from blood vessels to the site of injury
What is the function of neutrophils in the inflammation area?
Perform phagocytosis and kill microbes
Which process involves forming a network of fibrin threads to localize infection?
Fibrinogen clot formation
What is the role of antibodies in the immune system?
Block antigen receptors
Which protein complex forms a hole in the cell membrane during cell lysis?
Membrane attack complex
What stimulates histamine release and acts as a strong leukocyte chemoattractant?
Anaphylatoxins
What promotes phagocytosis by neutrophils and macrophages by binding to specific receptors?
Complement proteins
What are the harmful effects of inflammation?
Swelling of inflamed tissues with obstruction and loss of function
What is the main characteristic of hypersensitivity in inflammation?
Exaggerated response of inflammatory cells
What do selectins and integrins refer to in the context of inflammation?
Adhesion molecules on endothelial cells and leukocytes
What does opsonization refer to in the process of inflammation?
Enhancement of phagocytosis by coating pathogens
Which of the following best describes the role of complement in inflammation?
Enhancing phagocytosis and immune response
What is the main function of neutrophils and macrophages in the context of phagocytosis?
Remove waste materials from the area of inflammation
Which of the following factors help enhance phagocytosis alongside opsonins and complement?
Fibrin
What is the term for the process where a phagocyte engulfs a microbe after chemotaxis and adherence?
Phagocytosis
In chronic inflammation, which type of cells are typically present in higher numbers compared to acute inflammation?
Plasma cells
What is a common manifestation of acute inflammation microscopically when examining blood vessels?
BNL polymorphs
Which component of the immune system is involved in producing collagen during tissue repair in cases of chronic inflammation?
Tissue histiocytes
Test your knowledge on inflammation with this quiz by Prof. Dr. Mahmoud Tag from the Head of Pathology Department at MUST University. Learn about the definition, causes, mechanisms, morphologic changes, and complications of inflammation.
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